Bee Propolis 500mg | Canadian Apis mellifera | Antioxidant

Each vegetable capsule delivers 500mg of pure bee propolis (Apis mellifera L., Apidae) from Canadian honey bees. Provides antioxidants for the maintenance of good health. Health Canada licensed NPN 80033885. Gluten free. Dairy free. Soy free. Made in Canada. 120 vegetable capsules, 120 day supply at 1 capsule per day.

Source

Propolis collected by Canadian honey bees (Apis mellifera) from temperate zone botanical sources, predominantly poplar (Populus) tree buds. Canadian propolis is rich in flavonoids and phenolic acids derived from poplar resin, giving it a distinct antioxidant profile. The capsule shell is vegetable derived (HPMC), but propolis itself is an animal derived bee product and is not suitable for vegans.

What Is Bee Propolis?

Propolis is a resinous mixture that honey bees collect from tree buds and sap flows, mixed with beeswax, enzymes, and pollen. Bees use it to seal the hive, coat interior walls, and encapsulate foreign objects. The name comes from Greek meaning defense of the city. Canadian temperate zone propolis is predominantly poplar-derived, giving it a flavonoid and phenolic acid profile distinct from tropical propolis.

What Are the Active Compounds in Canadian Propolis?

The antioxidant activity of Canadian propolis comes from its flavonoids (pinocembrin, chrysin, galangin, quercetin) and phenolic acids (CAPE and ferulic acid). Pinocembrin is the most abundant flavanone in propolis. CAPE (caffeic acid phenethyl ester) is the most studied individual compound, with direct free radical scavenging activity and studied Nrf2 pathway activation, which upregulates the body's own antioxidant enzymes.

Key Benefits

• Provides antioxidants for the maintenance of good health Health Canada licensed claim under NPN 80033885
• 500mg bee propolis per capsule Apis mellifera L. | Canadian temperate zone propolis
• Source: Canadian Apis mellifera, poplar-derived Populus tree bud resin | Temperate zone flavonoid and phenolic acid profile
• Primary antioxidant compounds Pinocembrin, chrysin, galangin, quercetin | CAPE, ferulic acid
• Vegetable capsule Hydroxypropyl methylcellulose (HPMC) | No gelatin
• Health Canada licensed NPN 80033885 | GMP compliant | Made in Canada
• 120 vegetable capsules 120 day supply at 1 capsule per day

How It Works

Flavonoids and Free Radical Neutralization

Propolis flavonoids (pinocembrin, chrysin, galangin, quercetin) neutralize free radicals by donating hydrogen atoms from their hydroxyl groups and chelate pro oxidant metal ions such as iron and copper, reducing Fenton reaction-driven radical generation.

CAPE and the Nrf2 Pathway

CAPE directly scavenges free radicals and has been studied for Nrf2 pathway activation, which upregulates the body's own antioxidant enzymes including glutathione peroxidase, superoxide dismutase, and catalase, complementing the direct radical scavenging activity of the propolis flavonoids.

Why Canadian Propolis Has a Distinct Composition

Propolis composition reflects the local botanical environment. Canadian bees collect resin predominantly from poplar tree buds, which are rich in flavonoids and phenolic acids. This is why Canadian propolis has a high pinocembrin, chrysin, and CAPE content, and why the allergy caution specifically includes poplar tree products.

Why Balsam of Peru Cross-Reactivity Matters

Balsam of Peru contains many of the same phenolic compounds as propolis, including cinnamic acid and benzoic acid derivatives. Individuals sensitized to balsam of Peru often cross-react with propolis due to these shared compounds, which is the basis for the Health Canada caution.

Medicinal Ingredient (per capsule)

• Bee Propolis (Propolis, Apis mellifera L., Apidae) 500mg Source: Canadian honey bees, predominantly poplar-derived | Antioxidant | NPN 80033885

Non-medicinal ingredients: Hydroxypropyl methylcellulose (vegetable capsule shell). Gluten free. Dairy free. Soy free. Not suitable for vegans (propolis is an animal-derived bee product).

Quality and Trust

• NPN 80033885 Licensed by Health Canada as a Natural Health Product
• Made in Canada GMP compliant facility under Health Canada oversight
• Canadian Apis mellifera propolis Predominantly poplar-derived temperate zone composition
• Vegetable capsule HPMC shell, no gelatin
• Gluten free, dairy free, soy free
• 120 vegetable capsules 120 day supply at 1 capsule per day

Who This Is For

Adults seeking antioxidant support from a traditional bee derived botanical source, particularly those interested in the flavonoid and phenolic acid profile of Canadian temperate zone propolis. A good fit if you want a Health Canada licensed, Canadian made propolis supplement in a clean vegetable capsule with a once daily format.

Do not use if you are allergic to bee products, poplar tree products, or balsam of Peru. Not suitable for vegans. Talk to your healthcare practitioner before use if you are pregnant or breastfeeding, and for use beyond 1 month.

How to Use

Adults: Take 1 capsule, 1 time per day, or as directed by a healthcare practitioner. Consult a healthcare practitioner for use beyond 1 month.

Safety and Cautions

Consult a healthcare practitioner for use beyond 1 month. Do not use if you are allergic to bee products, poplar tree products, or balsam of Peru. Consult a healthcare practitioner before use if you are pregnant or breastfeeding. Hypersensitivity such as allergy has been known to occur; discontinue use immediately if it occurs. Store in a cool, dry place away from direct sunlight. Keep bottle tightly sealed. Do not use if the seal is broken or missing. Keep out of reach of children.

NPN 80033885. This product is not intended to diagnose, treat, cure, or prevent any disease. All health claims are consistent with Health Canada's Natural Health Products Regulations.