Resveratrol 500mg | 99% Trans-Resveratrol | Japanese Knotweed | 60 Vcaps — 6 Pack
A 6-pack of Resveratrol 500mg 500mg of 99% pure trans-resveratrol per vegan capsule, extracted from Japanese Knotweed root (Reynoutria japonica). Polyphenol antioxidant. Cellular health and cardiovascular wellness support. The most economical format available.
6 Pack at a Glance
- 360 vcaps total 6 bottles x 60 vcaps. Approximately 1-year supply at 1 vcap per day.
- 500mg trans-resveratrol per vcap 99% purity. Active stilbenoid form.
- Japanese Knotweed root source Reynoutria japonica. Highest natural plant concentration of trans-resveratrol.
- Health Canada licensed NPN 80140494 Made in Canada.
- Vegan capsule Hypromellose. No gelatin.
- Non-GMO. Gluten free. Dairy free.
- Lowest cost per bottle Most economical format available.
Recommended Use
Adults: 1 capsule daily, or as directed by a healthcare practitioner. Take with food. Consult a healthcare practitioner before use if you are pregnant or breastfeeding, have a hormone sensitive condition, or are taking medications including blood thinners or antiplatelet agents.
Why a Full Year of Trans-Resveratrol
Trans-resveratrol’s primary molecular target, SIRT1 (sirtuin-1), is a NAD⁺-dependent deacetylase that functions as a cellular energy and stress sensor. SIRT1 activity is directly coupled to the intracellular NAD⁺/NADH ratio a ratio that reflects the cell’s metabolic state and declines with age. By activating SIRT1, trans-resveratrol participates in a signalling network that includes PGC-1α (peroxisome proliferator-activated receptor gamma coactivator 1-alpha), the master regulator of mitochondrial biogenesis, and FOXO transcription factors involved in cellular stress resistance and longevity signalling.
These are not acute pharmacological effects they are adaptive transcriptional responses that require sustained SIRT1 activation over time to produce meaningful changes in mitochondrial density, antioxidant enzyme expression, and cellular stress resilience. The research literature on resveratrol and sirtuin biology consistently frames these outcomes in the context of long-term, uninterrupted daily supplementation rather than short courses.
Trans-resveratrol also modulates the AMPK (AMP-activated protein kinase) pathway a cellular energy sensor that works in concert with SIRT1 to regulate mitochondrial function and metabolic homeostasis. AMPK activation by resveratrol has been studied in the context of metabolic regulation and cardiovascular function, and like SIRT1-mediated effects, is most relevant when maintained consistently over an extended period.
The 6-pack provides a full year’s supply in a single purchase eliminating reorder decisions entirely, ensuring no interruptions to a daily trans-resveratrol routine, and delivering the lowest cost per bottle available for this formula.
Who This Is For
- Adults with a permanent daily trans-resveratrol routine who want a full year’s supply in a single purchase
- Those who want 360 days of 99% pure, Health Canada licensed trans-resveratrol from Japanese Knotweed without reordering
- Those seeking the absolute lowest cost per bottle on a vegan, non-GMO, Canadian made resveratrol supplement
Medicinal Ingredient (per vcap)
- Trans-Resveratrol (Reynoutria japonica, root) 500mg 99% purity. Japanese Knotweed. NPN 80140494.
Non-medicinal ingredient: Hypromellose (vegetable capsule shell). Vegan. Non-GMO. Gluten free. Dairy free.
Quality and Trust
- NPN 80140494 Licensed by Health Canada as a Natural Health Product
- Made in Canada
- 500mg trans-resveratrol per vcap 99% purity. Active stilbenoid form.
- Japanese Knotweed root Reynoutria japonica. Highest natural plant concentration.
- Vegan capsule Hypromellose. No gelatin.
- Non-GMO. Gluten free. Dairy free.
- 360 vcaps 6 x 60 vcaps. Lowest cost per bottle.
Storage
Store in a cool, dry place away from direct sunlight and moisture. Keep the bottle tightly sealed after each use. Do not use if the seal is broken or missing. Keep out of reach of children.
Cautions
Consult a healthcare practitioner before use if you are pregnant or breastfeeding, have a hormone-sensitive condition, or are taking blood-thinning or antiplatelet medications. Keep out of reach of children.
NPN 80140494.
Resveratrol 500mg | 99% Trans-Resveratrol | Japanese Knotweed | 60 Vcaps — 6 Pack
A 6-pack of Resveratrol 500mg 500mg of 99% pure trans-resveratrol per vegan capsule, extracted from Japanese Knotweed root (Reynoutria japonica). Polyphenol antioxidant. Cellular health and cardiovascular wellness support. The most economical format available.
6 Pack at a Glance
- 360 vcaps total 6 bottles x 60 vcaps. Approximately 1-year supply at 1 vcap per day.
- 500mg trans-resveratrol per vcap 99% purity. Active stilbenoid form.
- Japanese Knotweed root source Reynoutria japonica. Highest natural plant concentration of trans-resveratrol.
- Health Canada licensed NPN 80140494 Made in Canada.
- Vegan capsule Hypromellose. No gelatin.
- Non-GMO. Gluten free. Dairy free.
- Lowest cost per bottle Most economical format available.
Recommended Use
Adults: 1 capsule daily, or as directed by a healthcare practitioner. Take with food. Consult a healthcare practitioner before use if you are pregnant or breastfeeding, have a hormone sensitive condition, or are taking medications including blood thinners or antiplatelet agents.
Why a Full Year of Trans-Resveratrol
Trans-resveratrol’s primary molecular target, SIRT1 (sirtuin-1), is a NAD⁺-dependent deacetylase that functions as a cellular energy and stress sensor. SIRT1 activity is directly coupled to the intracellular NAD⁺/NADH ratio a ratio that reflects the cell’s metabolic state and declines with age. By activating SIRT1, trans-resveratrol participates in a signalling network that includes PGC-1α (peroxisome proliferator-activated receptor gamma coactivator 1-alpha), the master regulator of mitochondrial biogenesis, and FOXO transcription factors involved in cellular stress resistance and longevity signalling.
These are not acute pharmacological effects they are adaptive transcriptional responses that require sustained SIRT1 activation over time to produce meaningful changes in mitochondrial density, antioxidant enzyme expression, and cellular stress resilience. The research literature on resveratrol and sirtuin biology consistently frames these outcomes in the context of long-term, uninterrupted daily supplementation rather than short courses.
Trans-resveratrol also modulates the AMPK (AMP-activated protein kinase) pathway a cellular energy sensor that works in concert with SIRT1 to regulate mitochondrial function and metabolic homeostasis. AMPK activation by resveratrol has been studied in the context of metabolic regulation and cardiovascular function, and like SIRT1-mediated effects, is most relevant when maintained consistently over an extended period.
The 6-pack provides a full year’s supply in a single purchase eliminating reorder decisions entirely, ensuring no interruptions to a daily trans-resveratrol routine, and delivering the lowest cost per bottle available for this formula.
Who This Is For
- Adults with a permanent daily trans-resveratrol routine who want a full year’s supply in a single purchase
- Those who want 360 days of 99% pure, Health Canada licensed trans-resveratrol from Japanese Knotweed without reordering
- Those seeking the absolute lowest cost per bottle on a vegan, non-GMO, Canadian made resveratrol supplement
Medicinal Ingredient (per vcap)
- Trans-Resveratrol (Reynoutria japonica, root) 500mg 99% purity. Japanese Knotweed. NPN 80140494.
Non-medicinal ingredient: Hypromellose (vegetable capsule shell). Vegan. Non-GMO. Gluten free. Dairy free.
Quality and Trust
- NPN 80140494 Licensed by Health Canada as a Natural Health Product
- Made in Canada
- 500mg trans-resveratrol per vcap 99% purity. Active stilbenoid form.
- Japanese Knotweed root Reynoutria japonica. Highest natural plant concentration.
- Vegan capsule Hypromellose. No gelatin.
- Non-GMO. Gluten free. Dairy free.
- 360 vcaps 6 x 60 vcaps. Lowest cost per bottle.
Storage
Store in a cool, dry place away from direct sunlight and moisture. Keep the bottle tightly sealed after each use. Do not use if the seal is broken or missing. Keep out of reach of children.
Cautions
Consult a healthcare practitioner before use if you are pregnant or breastfeeding, have a hormone-sensitive condition, or are taking blood-thinning or antiplatelet medications. Keep out of reach of children.
NPN 80140494.