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Each capsule delivers 600 mg of chondroitin sulfate sourced from bovine cartilage (Bos taurus). The recommended daily dose of 2 capsules provides 1,200 mg of chondroitin sulfate the clinically studied amount for relief of knee pain associated with mild to moderate osteoarthritis.

What Is Chondroitin Sulfate?

Chondroitin sulfate (also spelled chondroitin sulphate; sulfate de chondroïtinе in French) is a glycosaminoglycan a structural component of cartilage found throughout the body’s joints, tendons, and connective tissue. It helps cartilage retain water, maintain its elasticity, and resist mechanical compression. As a key building block of articular cartilage, chondroitin sulfate contributes to joint cushioning, joint mobility, and long-term joint function. The body’s natural production of chondroitin sulfate declines with age, making supplementation increasingly relevant for cartilage support and joint health in adults.

Joint Health & Cartilage Support

Chondroitin sulfate 1,200 mg daily is the most studied dose in clinical trials on osteoarthritis and joint cartilage support. At this dose, chondroitin sulfate has been shown to help relieve knee pain associated with mild to moderate osteoarthritis and to support cartilage maintenance with consistent use. Health Canada has licensed this product (NPN 80124838) for relief of knee pain associated with mild to moderate osteoarthritis a specific therapeutic claim grounded in clinical evidence. This chondroitin supplement is sourced from bovine cartilage (Bos taurus), a well established source for high quality chondroitin sulfate capsules.

Chondroitin Sulfate 1200mg - Joint Health & Cartilage Support | 60 Capsules

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Each capsule delivers 600 mg of chondroitin sulfate sourced from bovine cartilage (Bos taurus). The recommended daily dose of 2 capsules provides 1,200 mg of chondroitin sulfate the clinically studied amount for relief of knee pain associated with mild to moderate osteoarthritis.

What Is Chondroitin Sulfate?

Chondroitin sulfate (also spelled chondroitin sulphate; sulfate de chondroïtinе in French) is a glycosaminoglycan a structural component of cartilage found throughout the body’s joints, tendons, and connective tissue. It helps cartilage retain water, maintain its elasticity, and resist mechanical compression. As a key building block of articular cartilage, chondroitin sulfate contributes to joint cushioning, joint mobility, and long-term joint function. The body’s natural production of chondroitin sulfate declines with age, making supplementation increasingly relevant for cartilage support and joint health in adults.

Joint Health & Cartilage Support

Chondroitin sulfate 1,200 mg daily is the most studied dose in clinical trials on osteoarthritis and joint cartilage support. At this dose, chondroitin sulfate has been shown to help relieve knee pain associated with mild to moderate osteoarthritis and to support cartilage maintenance with consistent use. Health Canada has licensed this product (NPN 80124838) for relief of knee pain associated with mild to moderate osteoarthritis a specific therapeutic claim grounded in clinical evidence. This chondroitin supplement is sourced from bovine cartilage (Bos taurus), a well established source for high quality chondroitin sulfate capsules.

Supplement Facts

Supplement Facts

Serving Size: 1 Capsule (Take Twice Daily)

Servings Per Container: 60

Ingredient
Amount Per
Serving
% Daily
Value
Chondroitin Sulfate (Bos taurus, Cartilage)
600 mg

† Daily Value not established

Other Ingredients:
Hypromellose (Vegetable Capsule Shell), Rice Flour, Magnesium Stearate (Vegetable Source)

Clinical Research

Glucosamine, chondroitin sulfate, and the two in combination for painful knee osteoarthritis

New England Journal of Medicine, 2006

This landmark randomized, double blind, placebo controlled multicentre trial the GAIT trial (Glucosamine/chondroitin Arthritis Intervention Trial) funded by the US National Institutes of Health, examined the effects of glucosamine, chondroitin sulfate, and their combination on knee pain from osteoarthritis in 1,583 patients. The study found that the combination of glucosamine and chondroitin sulfate produced statistically significant pain relief in the subgroup of patients with moderate to severe knee pain. Chondroitin sulfate alone showed a trend toward pain reduction. The GAIT trial is the largest and most cited clinical trial on chondroitin sulfate for osteoarthritis knee pain relief and cartilage support

Structure modifying effects of chondroitin sulfate in knee osteoarthritis: an updated meta analysis of randomized placebo controlled trials of 2 year duration

Annals of the Rheumatic Diseases, 2016

This updated meta analysis examined the structure modifying effects of chondroitin sulfate in knee osteoarthritis across randomized placebo controlled trials of 2 year duration. The analysis found that chondroitin sulfate significantly reduced joint space narrowing a radiographic marker of cartilage deterioration compared to placebo over 2 years. The authors concluded that chondroitin sulfate has both symptom-modifying effects (pain relief) and structure modifying effects (cartilage protection) in knee osteoarthritis, directly supporting its licensed uses for knee pain relief and cartilage support.

Chondroitin sulfate reduces both cartilage volume loss and bone marrow lesions in knee osteoarthritis patients starting as early as 6 months after initiation of therapy: a randomised, double blind, placebo controlled pilot study using MRI

Annals of the Rheumatic Diseases, 2011

This randomized, double blind, placebo controlled MRI study examined the structural effects of chondroitin sulfate supplementation on cartilage volume and bone marrow lesions in knee osteoarthritis patients over 6 months. The study found that chondroitin sulfate significantly reduced cartilage volume loss and bone marrow lesion size compared to placebo detectable by MRI as early as 6 months after initiation. The findings provide direct imaging evidence of chondroitin sulfate's cartilage-protective effects, supporting its role in protecting against cartilage deterioration and maintaining joint health.

Research information is provided for educational purposes and does not replace the product's approved label information.

Frequently Asked Questions

What is chondroitin sulfate and what does it do for joints?

Chondroitin sulfate is a glycosaminoglycan a complex carbohydrate that forms a key structural component of cartilage throughout the body, particularly in joints. It helps cartilage retain water, maintain its elasticity, and resist compression. As a structural molecule in the cartilage matrix, chondroitin sulfate is essential for cartilage hydration and cushioning between bones. This formula provides 600mg of chondroitin sulfate per capsule from bovine cartilage (Bos taurus) 1,200mg per daily dose of 2 capsules

What is the difference between chondroitin sulfate and glucosamine?

Glucosamine sulfate is an amino sugar and a direct building block of glycosaminoglycans (GAGs) the sugar chains that form the structural matrix of cartilage. Chondroitin sulfate is a larger glycosaminoglycan molecule that contributes to cartilage's water-retaining and compressive resistance properties it is the molecule that gives cartilage its ability to hold water and resist compression. Both are components of cartilage but work at different structural levels.

Where does this chondroitin sulfate come from?

This chondroitin sulfate is sourced from bovine cartilage (Bos taurus) the most well established and extensively researched source of chondroitin sulfate used in clinical trials. Bovine sourced chondroitin sulfate provides a high molecular weight glycosaminoglycan consistent with the form studied in osteoarthritis research

Can I take chondroitin sulfate with glucosamine and MSM?

Yes. Chondroitin sulfate, glucosamine, and MSM are commonly combined for broader joint support. Glucosamine provides the structural building block of cartilage glycosaminoglycans, MSM provides bioavailable organic sulfur for connective tissue, and chondroitin sulfate contributes to cartilage water retention and compressive resistance. The combination has been studied in clinical trials including the GAIT trial (Glucosamine/chondroitin Arthritis Intervention Trial). Consult a healthcare practitioner before combining supplements if you are taking anticoagulant medications.

What are the benefits of chondroitin sulfate for older adults?

Osteoarthritis is the most common form of arthritis and becomes increasingly prevalent with age the knee is one of the most commonly affected joints. As we age, the body's natural production of chondroitin sulfate declines, contributing to cartilage breakdown, reduced joint cushioning, and increased joint discomfort. Chondroitin sulfate supplementation at 1,200mg daily helps relieve knee pain associated with mild to moderate osteoarthritis, supports cartilage water retention and structural integrity, and supports joint mobility and long-term joint function.

Can younger adults and athletes take chondroitin sulfate?

Yes. While chondroitin sulfate is most commonly associated with osteoarthritis in older adults, it is also relevant for younger adults and athletes who place repetitive compressive loads on joints through exercise, sport, and physical work. Cartilage has limited blood supply and regenerative capacity supporting cartilage maintenance proactively is a reasonable approach for those with high joint demands. Consult a healthcare practitioner before use if taking medications or if you have a diagnosed joint condition.

Can chondroitin sulfate help with joint stiffness and mobility?

Chondroitin sulfate supports cartilage hydration the water retaining property of cartilage that gives joints their cushioning and range of motion. When cartilage loses water content and structural integrity, joint stiffness and reduced mobility are common consequences. By supporting cartilage water retention and structural maintenance, chondroitin sulfate supplementation supports joint flexibility and range of motion alongside knee pain relief.