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Each vegan capsule delivers 500โ€ฏmcg of elemental chromium from 4,030โ€ฏmcg of chromium picolinate the most extensively researched and bioavailable form of chromium supplement. This chromium picolinate 500mcg formula supports healthy glucose metabolism and glucose support by potentiating insulin signalling at the cellular level via chromodulin.ย 

What Is Chromium Picolinate?

Chromium picolinate is trivalent chromium (Cr3+) elemental chromium chelated with picolinic acid, a naturally occurring organic acid produced in the body as a tryptophan metabolite. Chelation with picolinic acid dramatically improves intestinal absorption compared to inorganic chromium chloride, which has bioavailability estimated at less than 1%. Chromium picolinate 500โ€ฏmcg (providing 500โ€ฏmcg elemental chromium from 4,030โ€ฏmcg chromium picolinate) is the dose used in the majority of peer reviewed human clinical trials on chromium and glucose metabolism support.

Glucose Metabolism Support How It Works

Chromium is a component of chromodulin, an oligopeptide that binds to the insulin receptor and amplifies its tyrosine kinase signalling activity. This enhances GLUT4 glucose transporter translocation to cell membranes, increasing cellular glucose uptake efficiency. Without adequate chromium, insulin signalling is less efficient and the body requires more insulin to maintain healthy blood glucose. By supporting this amplification step, this chromium supplement helps maintain healthy glucose metabolism and glucose support after meals and at fasting. A chromium 500โ€ฏmcg daily dose provides meaningful support for carbohydrate metabolism and insulin sensitivity as part of a consistent daily routine.

Chromium Picolinate 500mcg Elemental Chromium | Glucose Metabolism Support | 150 Vegan Capsules

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Health Canada Licensed Natural Health Product (NPN 80036350)

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Each vegan capsule delivers 500โ€ฏmcg of elemental chromium from 4,030โ€ฏmcg of chromium picolinate the most extensively researched and bioavailable form of chromium supplement. This chromium picolinate 500mcg formula supports healthy glucose metabolism and glucose support by potentiating insulin signalling at the cellular level via chromodulin.ย 

What Is Chromium Picolinate?

Chromium picolinate is trivalent chromium (Cr3+) elemental chromium chelated with picolinic acid, a naturally occurring organic acid produced in the body as a tryptophan metabolite. Chelation with picolinic acid dramatically improves intestinal absorption compared to inorganic chromium chloride, which has bioavailability estimated at less than 1%. Chromium picolinate 500โ€ฏmcg (providing 500โ€ฏmcg elemental chromium from 4,030โ€ฏmcg chromium picolinate) is the dose used in the majority of peer reviewed human clinical trials on chromium and glucose metabolism support.

Glucose Metabolism Support How It Works

Chromium is a component of chromodulin, an oligopeptide that binds to the insulin receptor and amplifies its tyrosine kinase signalling activity. This enhances GLUT4 glucose transporter translocation to cell membranes, increasing cellular glucose uptake efficiency. Without adequate chromium, insulin signalling is less efficient and the body requires more insulin to maintain healthy blood glucose. By supporting this amplification step, this chromium supplement helps maintain healthy glucose metabolism and glucose support after meals and at fasting. A chromium 500โ€ฏmcg daily dose provides meaningful support for carbohydrate metabolism and insulin sensitivity as part of a consistent daily routine.

Supplement Facts

Supplement Facts

Serving Size: 1 Capsule

Servings Per Container: 150

Ingredient
Amount Per
Serving
% Daily
Value
Chromium Picolinate
4,030 mcg
โ€ 
Elemental Chromium
500 mcg
14,286%

โ€  Daily Value not established

Other Ingredients:
Hypromellose (Vegetable Capsule Shell), Microcrystalline Cellulose, Magnesium Stearate (Vegetable Source)

Clinical Research

Effects of chromium picolinate supplementation on body composition, strength, and urinary chromium loss in football players

International Journal of Sport Nutrition, 1994

This study examined chromium picolinate supplementation in athletes under high physical stress a population with increased urinary chromium excretion and elevated chromium requirements. The research demonstrated that intense exercise increases chromium losses, supporting the rationale for chromium supplementation in physically active individuals seeking glucose metabolism and energy metabolism support.

A scientific review: the role of chromium in insulin resistance

Diabetes Education, 2006

This comprehensive scientific review examined the biochemical mechanism by which chromium supports insulin function. The review established that chromium activates chromodulin, which binds to the insulin receptor and amplifies its tyrosine kinase activity, enhancing GLUT4 glucose transporter translocation and cellular glucose uptake. The review concluded that chromium picolinate is the most bioavailable and most clinically validated form of supplemental chromium for glucose metabolism support.

Chromium picolinate supplementation attenuates body weight gain and increases insulin sensitivity in subjects with type 2 diabetes

Diabetes Care, 2006

This randomized controlled trial gave participants with type 2 diabetes chromium picolinate daily and measured insulin sensitivity and body weight over the study period. The study found that chromium picolinate supplementation significantly improved insulin sensitivity and attenuated body weight gain compared to placebo, directly supporting chromium picolinate's role in glucose metabolism and insulin signalling via the chromodulin mechanism.

Research information is provided for educational purposes and does not replace the product's approved label information.

Frequently Asked Questions

What is chromium picolinate used for?

Chromium picolinate is a highly bioavailable form of trivalent chromium (Cr3+) chelated with picolinic acid. It supports healthy glucose metabolism by potentiating insulin signalling at the cellular level via chromodulin. Licensed by Health Canada to support glucose metabolism (NPN 80036350). Each capsule provides 500mcg of elemental chromium from 4,030mcg of chromium picolinate.

What are the benefits of taking chromium picolinate?

Chromium picolinate supports healthy glucose metabolism by activating chromodulin, which amplifies insulin receptor signalling and enhances cellular glucose uptake. Benefits include support for healthy blood glucose levels within normal ranges, improved insulin sensitivity, and healthy carbohydrate and lipid metabolism. Each capsule provides 500mcg of elemental chromium from 4,030mcg of chromium picolinate the most bioavailable and most clinically researched form of supplemental chromium.

Who should take chromium picolinate and who should avoid it?

Chromium picolinate is suitable for healthy adults seeking glucose metabolism support, insulin sensitivity support, and healthy carbohydrate metabolism particularly those with dietary chromium gaps due to refined food diets, high physical stress, intense exercise, or increased physiological demand. Do not use without consulting a healthcare practitionerif you have diabetes or impaired glucose tolerance and are taking antidiabetic medications (insulin, metformin), have kidney or liver disease, are pregnant or breastfeeding, or are taking antacids, corticosteroids, or NSAIDs. Keep out of reach of children

Is chromium picolinate safe for diabetics?

Consult a healthcare practitioner before use if you have diabetes or impaired glucose tolerance and are taking antidiabetic medications including insulin or metformin. Chromium picolinate enhances insulin signalling combining it with antidiabetic medications requires medical supervision to avoid hypoglycemia. Not suitable for self medication of diabetes without professional guidance.

Does chromium picolinate help with blood sugar?

Chromium activates chromodulin, which amplifies insulin receptor signalling and enhances cellular glucose uptake, supporting healthy blood glucose within normal ranges. Suitable for adults with dietary chromium gaps due to refined food diets or high physical stress. Consult a healthcare practitioner before use if you have diabetes or are taking insulin or metformin. Licensed by Health Canada for glucose metabolism support (NPN 80036350)