GET 10% OFF FIRST ORDER

FREE SHIPPING OVER $55

Your cart

Your cart is empty

Hesperidin 500 mg is a concentrated citrus bioflavonoid supplement featuring a 90% citrus bioflavonoid extract. Supplied as a source of an antioxidant, the formula offers a convenient way to incorporate supplemental citrus bioflavonoids into a daily wellness routine.

What Is Hesperidin?

Hesperidin is a citrus bioflavonoid, a member of the plant flavonoid family. This supplement brings the ingredient into a concentrated capsule format, providing an alternative to powders that require measuring or mixing.

Concentrated Citrus Bioflavonoid Extract

The formula features a 90% citrus bioflavonoid extract, with 500 mg of the medicinal ingredient per capsule. Its composition focuses on hesperidin rather than combining multiple vitamins or minerals, making it a straightforward option for those seeking a dedicated citrus bioflavonoid supplement.

A Source of an Antioxidant

This hesperidin preparation provides a source of an antioxidant. It offers a focused choice for individuals who want to include citrus bioflavonoids in their supplement routine, without adding a broad multi ingredient blend.

Hesperidin 500 mg | Citrus Bioflavonoids | 60 Vcaps

Regular price $29.99
Unit price
per 

Shipping calculated at checkout.

Hesperidin 500 mg is a concentrated citrus bioflavonoid supplement featuring a 90% citrus bioflavonoid extract. Supplied as a source of an antioxidant, the formula offers a convenient way to incorporate supplemental citrus bioflavonoids into a daily wellness routine.

What Is Hesperidin?

Hesperidin is a citrus bioflavonoid, a member of the plant flavonoid family. This supplement brings the ingredient into a concentrated capsule format, providing an alternative to powders that require measuring or mixing.

Concentrated Citrus Bioflavonoid Extract

The formula features a 90% citrus bioflavonoid extract, with 500 mg of the medicinal ingredient per capsule. Its composition focuses on hesperidin rather than combining multiple vitamins or minerals, making it a straightforward option for those seeking a dedicated citrus bioflavonoid supplement.

A Source of an Antioxidant

This hesperidin preparation provides a source of an antioxidant. It offers a focused choice for individuals who want to include citrus bioflavonoids in their supplement routine, without adding a broad multi ingredient blend.

Supplement Facts

Supplement Facts

Serving Size: 1 capsule

Servings Per Container: 60

Ingredient
Amount Per
Serving
% Daily
Value
Hesperidin (citrus bioflavonoids)
500 mg
†

† Daily Value not established

Other Ingredients:
Hypromellose, magnesium stearate, microcrystalline cellulose.

Clinical Research

Hesperidin contributes to the vascular protective effects of orange juice: a randomized crossover study in healthy volunteers.

The American Journal of Clinical Nutrition, 2011

In a randomized crossover study, 24 healthy, moderately overweight men consumed orange juice, a control drink with hesperidin, or a control drink with placebo during three four week periods. Both orange juice and the hesperidin containing drink lowered diastolic blood pressure compared with placebo and improved microvascular reactivity after consumption. However, vascular reactivity measured after an overnight fast did not significantly improve. These findings concern short term vascular measurements, not demonstrated prevention of cardiovascular disease.

Effects of hesperidin supplementation on inflammation and oxidative stress in overweight or obese individuals: a systematic review and meta analysis of randomized controlled trials

Frontiers in Nutrition, 2026

This review combined 16 randomized controlled trials involving 845 participants. Hesperidin related interventions produced a modest reduction in C reactive protein, an inflammatory marker. Evidence for changes in other inflammatory and vascular markers was less certain, while total antioxidant capacity did not significantly improve. The authors considered oxidative stress findings inconclusive and could not recommend a specific dose or formulation.

Orange juice and hesperidin increase flavanone exposure without detectable short term vascular benefits: a randomized crossover trial.

Food & Function, 2026

Thirty seven centrally overweight men completed a randomized, double blind crossover trial comparing orange juice, a drink providing 210 mg of hesperidin daily, and a control beverage for six weeks each. Hesperidin increased exposure to its circulating metabolites, confirming absorption, but did not significantly improve flow mediated dilation or the measured vascular, metabolic, and body composition outcomes compared with control. This provides important balance to earlier positive vascular findings

Research information is provided for educational purposes and does not replace the product's approved label information.

Frequently Asked Questions

What is Hesperidin 500 mg?

Hesperidin is a naturally occurring citrus bioflavonoid found mainly in the peels and membranes of citrus fruits such as oranges and lemons. This formula provides 500 mg of hesperidin per specified serving.

What is Hesperidin used for?

Hesperidin is commonly used to support antioxidant protection, circulation, vascular health, and overall cardiovascular wellness.

What are citrus bioflavonoids?

Citrus bioflavonoids are naturally occurring plant compounds found in citrus fruits. They include hesperidin, rutin, naringin, and related flavonoids known for their antioxidant properties.

What are the benefits of Hesperidin?

Hesperidin is valued for its antioxidant activity and is commonly included in supplements designed to support healthy circulation, blood vessel function, and cardiovascular health.

Does Hesperidin provide antioxidant support?

Yes. Hesperidin is a flavonoid with antioxidant properties that can help protect cells against oxidative stress caused by free radicals.

How does Hesperidin support circulation?

Hesperidin is commonly studied for its potential role in supporting vascular function and healthy blood flow, making it a popular ingredient in circulation focused supplements.

Is Hesperidin the same as Vitamin C?

No. Hesperidin is a bioflavonoid, while Vitamin C is an essential vitamin. Both naturally occur in citrus fruits and are often combined in antioxidant and vascular Msupport supplements.