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Lutein and zeaxanthin are the only carotenoids that selectively accumulate in the human macula and lens. They form the macular pigment the eye’s primary internal filter for blue light and antioxidant defense for retinal tissue. The body cannot synthesize either one. Each capsule provides lutein 40 mg and zeaxanthin 5 mg from marigold flower extract (Tagetes erecta) the marigold extract lutein and zeaxanthin source used in the clinical research on macular carotenoids, and the most concentrated botanical source available.

Why Lutein and Zeaxanthin for Eyes

Lutein and zeaxanthin supplements work because these carotenoids concentrate specifically in the macula the central region of the retina responsible for sharp, detailed vision. Together they form the macular pigment, which filters blue light before it reaches photoreceptors and neutralizes free radicals generated by light exposure. Macular pigment density is directly related to dietary intake of lutein and zeaxanthin. Modern diets typically provide far less than the amounts associated with macular support, making lutein capsules a practical option for consistent daily intake.

Blue Light and Digital Screen Exposure

Digital screens, LED lighting, and fluorescent lighting all emit blue light that penetrates to the retina. Lutein zeaxanthin in the macular pigment absorb this blue light at the retinal level before it reaches photoreceptors. Higher macular pigment density is associated with improved contrast sensitivity and visual comfort during extended screen use making lutein and zeaxanthin supplements increasingly relevant for daily eye health.

High-Potency Formula

At lutein 40 mg and zeaxanthin 5 mg per capsule, this is a high potency lutein supplement two to four times the dose in many standard eye vitamins lutein zeaxanthin formulas. Both carotenoids are derived from marigold extract (Tagetes erecta). Fat-soluble: take with a meal containing dietary fat for optimal absorption.

Lutein 40mg + Zeaxanthin 5mg - Marigold Extract | Eye Health | 60 Vcaps

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Lutein and zeaxanthin are the only carotenoids that selectively accumulate in the human macula and lens. They form the macular pigment the eye’s primary internal filter for blue light and antioxidant defense for retinal tissue. The body cannot synthesize either one. Each capsule provides lutein 40 mg and zeaxanthin 5 mg from marigold flower extract (Tagetes erecta) the marigold extract lutein and zeaxanthin source used in the clinical research on macular carotenoids, and the most concentrated botanical source available.

Why Lutein and Zeaxanthin for Eyes

Lutein and zeaxanthin supplements work because these carotenoids concentrate specifically in the macula the central region of the retina responsible for sharp, detailed vision. Together they form the macular pigment, which filters blue light before it reaches photoreceptors and neutralizes free radicals generated by light exposure. Macular pigment density is directly related to dietary intake of lutein and zeaxanthin. Modern diets typically provide far less than the amounts associated with macular support, making lutein capsules a practical option for consistent daily intake.

Blue Light and Digital Screen Exposure

Digital screens, LED lighting, and fluorescent lighting all emit blue light that penetrates to the retina. Lutein zeaxanthin in the macular pigment absorb this blue light at the retinal level before it reaches photoreceptors. Higher macular pigment density is associated with improved contrast sensitivity and visual comfort during extended screen use making lutein and zeaxanthin supplements increasingly relevant for daily eye health.

High-Potency Formula

At lutein 40 mg and zeaxanthin 5 mg per capsule, this is a high potency lutein supplement two to four times the dose in many standard eye vitamins lutein zeaxanthin formulas. Both carotenoids are derived from marigold extract (Tagetes erecta). Fat-soluble: take with a meal containing dietary fat for optimal absorption.

Supplement Facts

Supplement Facts

Serving Size: 1 Capsule

Servings Per Container: 60

Ingredient
Amount Per
Serving
% Daily
Value
Lutein (Tagetes erecta, Marigold Flower Extract)
40 mg
Zeaxanthin (Tagetes erecta, Marigold Flower Extract)
5 mg

† Daily Value not established

Other Ingredients:
Hypromellose (Vegetable Capsule Shell), Microcrystalline Cellulose, Magnesium Stearate

Clinical Research

Lutein + zeaxanthin and omega-3 fatty acids for age related macular degeneration: the Age Related Eye Disease Study 2 (AREDS2) randomized clinical trial

JAMA, 2013

This landmark randomized controlled trial (AREDS2) examined the effects of lutein (10mg) and zeaxanthin (2mg) supplementation on macular health in adults at risk for advanced age related macular degeneration. The study found that lutein and zeaxanthin supplementation significantly reduced the risk of progression to advanced macular degeneration compared to placebo, and that the lutein/zeaxanthin combination was superior to beta carotene for macular health support. The AREDS2 trial established lutein and zeaxanthin as the carotenoids of choice for macular health supplementation.

Macular pigment optical density is related to cognitive function in older adults

Nutrients, 2017

This study examined the relationship between macular pigment optical density (MPOD) the measurable marker of lutein and zeaxanthin status in the eye and visual function in adults. The research found that higher MPOD was associated with better contrast sensitivity, reduced glare sensitivity, and improved visual performance under challenging lighting conditions. The authors confirmed that lutein and zeaxanthin supplementation increases MPOD and supports visual acuity and contrast sensitivity in adults with low baseline macular pigment.

Lutein and zeaxanthin supplementation reduces photooxidative damage and modulates the expression of inflammation related genes in retinal pigment epithelial cells

Free Radical Biology and Medicine, 2012

This study examined the mechanisms by which lutein and zeaxanthin protect retinal cells from blue light induced oxidative damage. The research found that lutein and zeaxanthin absorbed high-energy blue light and reduced photooxidative damage to retinal pigment epithelial cells, and modulated the expression of oxidative stress and inflammation-related genes. The authors confirmed that the macular carotenoids provide both optical filtering and direct antioxidant protection to retinal tissue, supporting their role in macular health and blue light protection.

Research information is provided for educational purposes and does not replace the product's approved label information.

Frequently Asked Questions

What are lutein and zeaxanthin and what are they used for?

Lutein and zeaxanthin are carotenoid pigments that concentrate selectively in the macula and lens of the human eye, forming the macular pigment. They filter harmful high energy blue light before it reaches the photoreceptors, and act as antioxidants protecting retinal cells from oxidative damage. Lutein and zeaxanthin supplements support macular health, visual acuity, and contrast sensitivity, and are particularly relevant for adults with high blue light exposure from digital screens. Consult a healthcare practitioner before use.

Why take 40mg lutein and 5mg zeaxanthin?

The 40mg lutein / 5mg zeaxanthin ratio reflects the naturally occurring ratio of these carotenoids in the macula (approximately 8:1 lutein to zeaxanthin) and is the dose used in the AREDS2 clinical trial the landmark study that established lutein and zeaxanthin as the carotenoids of choice for macular health support. This high-potency dose is designed to meaningfully increase macular pigment optical density (MPOD), the measurable marker of macular carotenoid status.

What is macular pigment and why does it matter?

Macular pigment is the yellow pigment formed by the selective accumulation of lutein and zeaxanthin in the macula the central region of the retina responsible for sharp, detailed central vision. Macular pigment optical density (MPOD) is the measurable marker of macular carotenoid status. Higher MPOD is associated with better contrast sensitivity, reduced glare sensitivity, and greater protection against blue light induced oxidative damage to photoreceptors. MPOD can be increased through consistent lutein and zeaxanthin supplementation.

How does lutein protect against blue light?

Lutein and zeaxanthin absorb high energy blue light (wavelengths approximately 400–500nm) before it reaches the photoreceptors in the macula. This optical filtering reduces the amount of blue light induced oxidative stress on retinal cells. As digital screen use increases daily blue light exposure, macular pigment density becomes increasingly relevant for long term visual health. Lutein and zeaxanthin supplementation supports macular pigment density and blue light filtration capacity.

Why must lutein and zeaxanthin be taken with fat?

Lutein and zeaxanthin are fat-soluble carotenoids. Like all fat soluble nutrients, they require dietary fat for micellar solubilization in the small intestine and absorption into the lymphatic system. Taking lutein and zeaxanthin with a fat free meal significantly reduces absorption. Even a small amount of dietary fat (5–10g) is sufficient to support absorption a meal containing olive oil, avocado, nuts, or any fat-containing food is appropriate.

Are lutein and zeaxanthin safe for long-term daily use?

Lutein and zeaxanthin have an excellent safety profile with no established tolerable upper intake level. They are naturally occurring carotenoids found in leafy green vegetables and eggs, and have been studied in clinical trials at doses up to 20mg lutein daily for extended periods without adverse effects. High dose supplementation (40mg lutein) may cause carotenodermia a harmless yellowing of the skin in some individuals. Consult a healthcare practitioner for long-term use guidance.