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Vitamin B complex max active forms 120 vegan capsules
Vitamin B complex max supplement active B vitamins capsules
Vitamin B complex max supplement bottle 120 vcaps
Vitamin B complex max active forms dietary supplement
Vitamin B complex max daily wellness supplement 120 capsules
Vitamin B complex max supplement facts label capsules
Vitamin B complex max active forms 120 vegan capsules

B Complex MAX | Active Forms | 10 B Vitamins | L-5-MTHF and Methylcobalamin | 120 Vegan Capsules

Every B vitamin in its active form. L-5-methyltetrahydrofolate (not folic acid). Methylcobalamin (not cyanocobalamin). Pyridoxal-5-phosphate (not pyridoxine HCl). D-pantethine (not calcium pantothenate). Riboflavin-5-phosphate (not riboflavin). Benfotiamine (not thiamine HCl).

Key Benefits

  • Helps in energy metabolism and tissue formation Health Canada licensed use under NPN 80112908
  • Helps to form red blood cells NPN 80112908
  • Helps maintain healthy hair, nails, mucous membranes and skin NPN 80112908
  • L-5-MTHF 1,000mcg Active folate (B9). Directly usable without MTHFR enzyme conversion.
  • Methylcobalamin 1,000mcg Active B12. Directly bioavailable.
  • Pyridoxal-5-phosphate (P-5-P) 100mg Active B6. No hepatic conversion required. At the tolerable upper intake level do not exceed recommended dose.
  • D-Pantethine 30mg Active B5. Direct precursor to coenzyme A.
  • Riboflavin-5-phosphate (R5P) 30mg Active B2. Immediately bioavailable coenzyme form.
  • Benfotiamine 30mg Fat-soluble B1. Superior tissue penetration versus thiamine HCl.
  • Vegan capsule Hypromellose. No gelatin.
  • Health Canada licensed NPN 80112908 Vegan. Non-GMO. Gluten free. Soy free. Made in Canada.
  • 120 vcaps 120 day supply at 1 capsule per day

Recommended Use

Adults: Take 1 capsule once daily with food. Do not exceed the recommended dose. Taking with food improves absorption and reduces the chance of nausea that can occur with high-dose B vitamins on an empty stomach.

Note: Riboflavin-5-phosphate (B2) may cause bright yellow urine. This is a normal and harmless effect of riboflavin metabolism.

Who This Is For

  • Adults who specifically require active forms throughout their B complex, particularly L-5-MTHF (not folic acid) and P-5-P (not pyridoxine HCl)
  • Those with known or suspected MTHFR variants who cannot efficiently convert folic acid to L-5-MTHF
  • Adults who want methylcobalamin at 1,000mcg and L-5-MTHF at 1,000mcg in a single daily capsule
  • Vegans and vegetarians who want a fully active-form B complex with methylcobalamin B12
  • Adults who have reviewed the B6 at 100mg consideration and understand the importance of not exceeding the recommended dose

Consult a healthcare practitioner before use if you are pregnant or breastfeeding, or if you are taking medications.

The Active Forms: Why Each Choice Was Made

B9 | L-5-Methyltetrahydrofolate (L-5-MTHF) | 1,000mcg

Most B complex supplements use folic acid, a synthetic form that must be converted to L-5-MTHF through a multi-step process involving the MTHFR enzyme. Approximately 40 to 60% of the population carries a genetic variant in the MTHFR gene that reduces this conversion by 30 to 70%. L-5-MTHF is the form directly used by the body for methylation reactions, including the remethylation of homocysteine to methionine. This formula provides 1,000mcg of L-5-MTHF, bypassing the MTHFR conversion step entirely.

B12 | Methylcobalamin | 1,000mcg

Methylcobalamin is the active coenzyme form of B12 found in human blood and tissues. Unlike cyanocobalamin, it does not require hepatic conversion and is directly bioavailable. It is better retained in nervous system tissue and functions directly as a cofactor for methionine synthase in the remethylation of homocysteine to methionine.

B6 | Pyridoxal-5-Phosphate (P-5-P) | 100mg

P-5-P is the active coenzyme form of vitamin B6, directly bioavailable without requiring hepatic conversion from pyridoxine HCl. At 100mg, this formula provides B6 at the tolerable upper intake level. Do not exceed the recommended dose of 1 capsule per day.

B5 | D-Pantethine | 30mg

D-Pantethine is the active, reduced form of pantothenic acid and a direct precursor to coenzyme A (CoA) central to the citric acid cycle, fatty acid metabolism, and the synthesis of steroid hormones and neurotransmitters. Standard B5 supplements use calcium pantothenate, which requires an additional conversion step.

B2 | Riboflavin-5-Phosphate (R5P) | 30mg

R5P is the active coenzyme form of riboflavin, immediately bioavailable as a component of FMN and FAD coenzymes essential for the electron transport chain, fatty acid oxidation, and glutathione recycling. Standard riboflavin must be phosphorylated before it can be utilized.

B1 | Benfotiamine | 30mg

Benfotiamine is a fat-soluble derivative of thiamine with significantly higher oral bioavailability than standard water-soluble thiamine salts. Because it is fat-soluble, it achieves higher blood and tissue concentrations and is better retained in tissues including nervous system tissue.

B3 | Inositol Hexanicotinate | 30mg

Inositol hexanicotinate releases niacin more slowly than standard nicotinic acid, reducing the prostaglandin-mediated skin flushing associated with standard niacin. Note: individuals sensitive to nicotinic acid may still experience mild, transient flushing.

B7 | Biotin | 50mcg

Biotin is provided at 50mcg a nutritional support level consistent with daily wellness use, without the laboratory test interference risk associated with high dose biotin supplementation.

Inositol | Myo-Inositol | 100mg

Myo inositol is the most abundant and biologically active form of inositol in the body. It functions as a component of phosphatidylinositol, a cell membrane phospholipid involved in intracellular signaling including insulin signal transduction and serotonin receptor function.

Choline | Choline Bitartrate | 30mg

Choline is an essential nutrient and precursor to acetylcholine (a neurotransmitter involved in memory and neuromuscular function) and phosphatidylcholine (a primary structural component of cell membranes). Choline bitartrate is a stable, well-absorbed salt form.

Storage

Store in a cool, dry place away from direct sunlight and moisture. Keep the bottle tightly sealed after each use. Do not use if the seal is broken or missing. Keep out of reach of children.

Cautions

Do not exceed the recommended dose of 1 capsule per day. This formula provides vitamin B6 (as P-5-P) at 100mg the tolerable upper intake level for adults. Long-term intake of vitamin B6 above the tolerable upper intake level can cause peripheral neuropathy. Do not combine with other supplements containing vitamin B6 without consulting a healthcare practitioner.

Individuals sensitive to nicotinic acid may experience mild, transient skin flushing due to the inositol hexanicotinate (B3) in this formula. Consult a healthcare practitioner before use if you are pregnant or breastfeeding, or if you are taking medications. Keep out of reach of children.

NPN 80112908.

B Complex MAX | Active Forms | 10 B Vitamins | L-5-MTHF and Methylcobalamin | 120 Vegan Capsules

$39.99
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Health Canada Licensed Natural Health Product (NPN 80112908)

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B Complex MAX | Active Forms | 10 B Vitamins | L-5-MTHF and Methylcobalamin | 120 Vegan Capsules

Every B vitamin in its active form. L-5-methyltetrahydrofolate (not folic acid). Methylcobalamin (not cyanocobalamin). Pyridoxal-5-phosphate (not pyridoxine HCl). D-pantethine (not calcium pantothenate). Riboflavin-5-phosphate (not riboflavin). Benfotiamine (not thiamine HCl).

Key Benefits

  • Helps in energy metabolism and tissue formation Health Canada licensed use under NPN 80112908
  • Helps to form red blood cells NPN 80112908
  • Helps maintain healthy hair, nails, mucous membranes and skin NPN 80112908
  • L-5-MTHF 1,000mcg Active folate (B9). Directly usable without MTHFR enzyme conversion.
  • Methylcobalamin 1,000mcg Active B12. Directly bioavailable.
  • Pyridoxal-5-phosphate (P-5-P) 100mg Active B6. No hepatic conversion required. At the tolerable upper intake level do not exceed recommended dose.
  • D-Pantethine 30mg Active B5. Direct precursor to coenzyme A.
  • Riboflavin-5-phosphate (R5P) 30mg Active B2. Immediately bioavailable coenzyme form.
  • Benfotiamine 30mg Fat-soluble B1. Superior tissue penetration versus thiamine HCl.
  • Vegan capsule Hypromellose. No gelatin.
  • Health Canada licensed NPN 80112908 Vegan. Non-GMO. Gluten free. Soy free. Made in Canada.
  • 120 vcaps 120 day supply at 1 capsule per day

Recommended Use

Adults: Take 1 capsule once daily with food. Do not exceed the recommended dose. Taking with food improves absorption and reduces the chance of nausea that can occur with high-dose B vitamins on an empty stomach.

Note: Riboflavin-5-phosphate (B2) may cause bright yellow urine. This is a normal and harmless effect of riboflavin metabolism.

Who This Is For

  • Adults who specifically require active forms throughout their B complex, particularly L-5-MTHF (not folic acid) and P-5-P (not pyridoxine HCl)
  • Those with known or suspected MTHFR variants who cannot efficiently convert folic acid to L-5-MTHF
  • Adults who want methylcobalamin at 1,000mcg and L-5-MTHF at 1,000mcg in a single daily capsule
  • Vegans and vegetarians who want a fully active-form B complex with methylcobalamin B12
  • Adults who have reviewed the B6 at 100mg consideration and understand the importance of not exceeding the recommended dose

Consult a healthcare practitioner before use if you are pregnant or breastfeeding, or if you are taking medications.

The Active Forms: Why Each Choice Was Made

B9 | L-5-Methyltetrahydrofolate (L-5-MTHF) | 1,000mcg

Most B complex supplements use folic acid, a synthetic form that must be converted to L-5-MTHF through a multi-step process involving the MTHFR enzyme. Approximately 40 to 60% of the population carries a genetic variant in the MTHFR gene that reduces this conversion by 30 to 70%. L-5-MTHF is the form directly used by the body for methylation reactions, including the remethylation of homocysteine to methionine. This formula provides 1,000mcg of L-5-MTHF, bypassing the MTHFR conversion step entirely.

B12 | Methylcobalamin | 1,000mcg

Methylcobalamin is the active coenzyme form of B12 found in human blood and tissues. Unlike cyanocobalamin, it does not require hepatic conversion and is directly bioavailable. It is better retained in nervous system tissue and functions directly as a cofactor for methionine synthase in the remethylation of homocysteine to methionine.

B6 | Pyridoxal-5-Phosphate (P-5-P) | 100mg

P-5-P is the active coenzyme form of vitamin B6, directly bioavailable without requiring hepatic conversion from pyridoxine HCl. At 100mg, this formula provides B6 at the tolerable upper intake level. Do not exceed the recommended dose of 1 capsule per day.

B5 | D-Pantethine | 30mg

D-Pantethine is the active, reduced form of pantothenic acid and a direct precursor to coenzyme A (CoA) central to the citric acid cycle, fatty acid metabolism, and the synthesis of steroid hormones and neurotransmitters. Standard B5 supplements use calcium pantothenate, which requires an additional conversion step.

B2 | Riboflavin-5-Phosphate (R5P) | 30mg

R5P is the active coenzyme form of riboflavin, immediately bioavailable as a component of FMN and FAD coenzymes essential for the electron transport chain, fatty acid oxidation, and glutathione recycling. Standard riboflavin must be phosphorylated before it can be utilized.

B1 | Benfotiamine | 30mg

Benfotiamine is a fat-soluble derivative of thiamine with significantly higher oral bioavailability than standard water-soluble thiamine salts. Because it is fat-soluble, it achieves higher blood and tissue concentrations and is better retained in tissues including nervous system tissue.

B3 | Inositol Hexanicotinate | 30mg

Inositol hexanicotinate releases niacin more slowly than standard nicotinic acid, reducing the prostaglandin-mediated skin flushing associated with standard niacin. Note: individuals sensitive to nicotinic acid may still experience mild, transient flushing.

B7 | Biotin | 50mcg

Biotin is provided at 50mcg a nutritional support level consistent with daily wellness use, without the laboratory test interference risk associated with high dose biotin supplementation.

Inositol | Myo-Inositol | 100mg

Myo inositol is the most abundant and biologically active form of inositol in the body. It functions as a component of phosphatidylinositol, a cell membrane phospholipid involved in intracellular signaling including insulin signal transduction and serotonin receptor function.

Choline | Choline Bitartrate | 30mg

Choline is an essential nutrient and precursor to acetylcholine (a neurotransmitter involved in memory and neuromuscular function) and phosphatidylcholine (a primary structural component of cell membranes). Choline bitartrate is a stable, well-absorbed salt form.

Storage

Store in a cool, dry place away from direct sunlight and moisture. Keep the bottle tightly sealed after each use. Do not use if the seal is broken or missing. Keep out of reach of children.

Cautions

Do not exceed the recommended dose of 1 capsule per day. This formula provides vitamin B6 (as P-5-P) at 100mg the tolerable upper intake level for adults. Long-term intake of vitamin B6 above the tolerable upper intake level can cause peripheral neuropathy. Do not combine with other supplements containing vitamin B6 without consulting a healthcare practitioner.

Individuals sensitive to nicotinic acid may experience mild, transient skin flushing due to the inositol hexanicotinate (B3) in this formula. Consult a healthcare practitioner before use if you are pregnant or breastfeeding, or if you are taking medications. Keep out of reach of children.

NPN 80112908.

Supplement Facts

Supplement Facts

Serving Size: 1 Capsule

Servings Per Container: 120

Ingredient
Amount Per
Serving
% Daily
Value
Thiamine (Vitamin B1, as Benfotiamine)
30 mg
2,500%
Riboflavin (Vitamin B2, as Riboflavin-5'-Phosphate)
30 mg
2,308%
Niacin (Vitamin B3, as Inositol Hexanicotinate)
30 mg
188%
Choline (as Choline Bitartrate)
30 mg
5%
Pantothenic Acid (Vitamin B5, as D-Pantethine)
30 mg
600%
Vitamin B6 (as Pyridoxal-5'-Phosphate)
100 mg
5,882%
Biotin (Vitamin B7)
50 mcg
167%
Inositol (as Myo-Inositol)
100 mg
†
Folate (Vitamin B9, as L-5-Methyltetrahydrofolate)
1,000 mcg DFE
250%
Vitamin B12 (as Methylcobalamin)
1,000 mcg
41,667%

† Daily Value not established

Other Ingredients:
Microcrystalline Cellulose, Magnesium Stearate, Hypromellose (Vegetable Capsule Shell)

Clinical Research

MTHFR gene variants and folate metabolism: implications for supplementation with L-5-methyltetrahydrofolate

Nutrients, 2017

This review examined the prevalence and metabolic consequences of MTHFR gene variants (C677T and A1298C) and their impact on folic acid conversion to L-5-MTHF. The review found that approximately 40–60% of the population carries at least one MTHFR variant, reducing folic acid conversion efficiency by 30–70%. The authors confirmed that L-5-MTHF supplementation bypasses the MTHFR conversion step entirely and is directly bioavailable regardless of MTHFR genotype, concluding that L-5-MTHF is the preferred form of folate supplementation for individuals with known or suspected MTHFR variants.

Methylcobalamin: a potential vitamin of pain killer

Neural Plasticity, 2013

This review examined the pharmacokinetics and bioavailability of methylcobalamin compared to cyanocobalamin, documenting that methylcobalamin is better retained in nervous system tissue, does not require hepatic conversion, and functions directly as a cofactor for methionine synthase in homocysteine remethylation. The review confirmed that methylcobalamin achieves higher tissue concentrations in the brain and nervous system compared to cyanocobalamin at equivalent doses, and concluded that methylcobalamin is the preferred form of B12 supplementation for neurological and methylation support.

Benfotiamine: a synthetic S-acyl thiamine derivative that has different mechanisms of action and pharmacokinetics than lipophilic thiamine disulfide derivatives

Nutrients, 2016

This review examined the pharmacokinetics of benfotiamine compared to standard thiamine salts, documenting that benfotiamine achieves significantly higher blood and tissue thiamine concentrations due to its fat-soluble structure and passive absorption mechanism. The review confirmed that benfotiamine is more efficiently absorbed and better retained in tissues including nervous system tissue compared to water soluble thiamine HCl, and concluded that benfotiamine is the preferred form of thiamine supplementation when high tissue bioavailability is the goal.

Research information is provided for educational purposes and does not replace the product's approved label information.

Frequently Asked Questions

What does "active forms" mean for B vitamins?

Most B vitamins in standard supplements are provided as precursor forms that must be converted by the body into their active coenzyme forms before they can be used. For example, folic acid must be converted to L-5-MTHF, cyanocobalamin must be converted to methylcobalamin, and pyridoxine HCl must be converted to pyridoxal-5-phosphate. Active forms bypass these conversion steps they are the forms the body uses directly. This matters most for individuals with genetic variants (such as MTHFR) or metabolic conditions that impair these conversions.

What is L-5-MTHF and why is it used instead of folic acid?

L-5-methyltetrahydrofolate (L-5-MTHF) is the active, directly bioavailable form of folate (B9) found in human blood and tissues. Standard B complex supplements use folic acid a synthetic form that must be converted to L-5-MTHF through a multi step process involving the MTHFR enzyme. Approximately 40–60% of the population carries a genetic variant in the MTHFR gene that reduces this conversion by 30–70%, meaning a significant portion of the population cannot efficiently utilize folic acid. L-5-MTHF bypasses the MTHFR conversion step entirely, providing 1,000mcg of directly usable active folate per capsule.

What is methylcobalamin and why is it used instead of cyanocobalamin?

Methylcobalamin is the active coenzyme form of vitamin B12 found in human blood and nervous system tissue. Unlike cyanocobalamin (the most common synthetic B12 form), methylcobalamin does not require hepatic conversion and is directly bioavailable. It is better retained in nervous system tissue and functions directly as a cofactor for methionine synthase in the remethylation of homocysteine to methionine a critical methylation reaction

What is pyridoxal-5-phosphate (P-5-P) and why does the dose matter?

Pyridoxal-5-phosphate (P-5-P) is the active coenzyme form of vitamin B6, directly bioavailable without requiring hepatic conversion from pyridoxine HCl. This formula provides P-5-P at 100mg per capsule the tolerable upper intake level (UL) for vitamin B6 in adults. Do not exceed the recommended dose of 1 capsule per day. Do not combine with other supplements containing vitamin B6 without consulting a healthcare practitioner. Long term intake of vitamin B6 above the tolerable upper intake level can cause peripheral neuropathy.

What is benfotiamine and how is it different from standard thiamine?

Benfotiamine is a fat soluble derivative of thiamine (vitamin B1) with significantly higher oral bioavailability than standard water soluble thiamine salts (thiamine HCl or thiamine mononitrate). Because it is fat soluble, benfotiamine achieves higher blood and tissue concentrations and is better retained in tissues including nervous system tissue. Standard thiamine is water soluble and is rapidly excreted. Benfotiamine provides 30mg of fat soluble B1 per capsule.

Why does B Complex MAX include inositol and choline?

nositol (myo inositol, 100mg) and choline (choline bitartrate, 30mg) are not technically B vitamins but are closely associated with the B vitamin family and are included for their complementary roles in cellular function. Myo inositol is a component of phosphatidylinositol a cell membrane phospholipid involved in intracellular signaling including insulin signal transduction and serotonin receptor function. Choline is an essential nutrient and precursor to acetylcholine (a neurotransmitter involved in memory and neuromuscular function) and phosphatidylcholine (a primary structural component of cell membranes).

How do you take B Complex MAX?

Adults: take 1 capsule once per day with food. Taking with food improves absorption and reduces the chance of nausea that can occur with high dose B vitamins on an empty stomach. Do not exceed the recommended dose of 1 capsule per day this formula provides vitamin B6 (as P-5-P) at 100mg, the tolerable upper intake level. A 120-capsule bottle provides a 120-day (4-month) supply at 1 capsule per day.

Who should not take B Complex MAX?

Do not exceed the recommended dose of 1 capsule per day. Do not combine with other supplements containing vitamin B6 without consulting a healthcare practitioner this formula already provides B6 at the tolerable upper intake level. Consult a healthcare practitioner before use if you are pregnant or breastfeeding, or if you are taking medications. Individuals sensitive to nicotinic acid may experience mild, transient skin flushing due to the inositol hexanicotinate (B3) in this formula. Keep out of reach of children.

Canadian-Made

Lab-Tested

Health Canada Approved

20 Years of Research

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