Complexe B MAX | L-5-MTHF et méthylcobalamine | 120 gélules véganes

Most B vitamins in standard supplements are provided as precursor forms that must be converted by the body into their active coenzyme forms before they can be used. For example, folic acid must be converted to L-5-MTHF, cyanocobalamin must be converted to methylcobalamin, and pyridoxine HCl must be converted to pyridoxal-5-phosphate. Active forms bypass these conversion steps they are the forms the body uses directly. This matters most for individuals with genetic variants (such as MTHFR) or metabolic conditions that impair these conversions.

L-5-methyltetrahydrofolate (L-5-MTHF) is the active, directly bioavailable form of folate (B9) found in human blood and tissues. Standard B complex supplements use folic acid a synthetic form that must be converted to L-5-MTHF through a multi step process involving the MTHFR enzyme. Approximately 40–60% of the population carries a genetic variant in the MTHFR gene that reduces this conversion by 30–70%, meaning a significant portion of the population cannot efficiently utilize folic acid. L-5-MTHF bypasses the MTHFR conversion step entirely, providing 1,000mcg of directly usable active folate per capsule.

Methylcobalamin is the active coenzyme form of vitamin B12 found in human blood and nervous system tissue. Unlike cyanocobalamin (the most common synthetic B12 form), methylcobalamin does not require hepatic conversion and is directly bioavailable. It is better retained in nervous system tissue and functions directly as a cofactor for methionine synthase in the remethylation of homocysteine to methionine a critical methylation reaction

Pyridoxal-5-phosphate (P-5-P) is the active coenzyme form of vitamin B6, directly bioavailable without requiring hepatic conversion from pyridoxine HCl. This formula provides P-5-P at 100mg per capsule the tolerable upper intake level (UL) for vitamin B6 in adults. Do not exceed the recommended dose of 1 capsule per day. Do not combine with other supplements containing vitamin B6 without consulting a healthcare practitioner. Long term intake of vitamin B6 above the tolerable upper intake level can cause peripheral neuropathy.

Benfotiamine is a fat soluble derivative of thiamine (vitamin B1) with significantly higher oral bioavailability than standard water soluble thiamine salts (thiamine HCl or thiamine mononitrate). Because it is fat soluble, benfotiamine achieves higher blood and tissue concentrations and is better retained in tissues including nervous system tissue. Standard thiamine is water soluble and is rapidly excreted. Benfotiamine provides 30mg of fat soluble B1 per capsule.

nositol (myo inositol, 100mg) and choline (choline bitartrate, 30mg) are not technically B vitamins but are closely associated with the B vitamin family and are included for their complementary roles in cellular function. Myo inositol is a component of phosphatidylinositol a cell membrane phospholipid involved in intracellular signaling including insulin signal transduction and serotonin receptor function. Choline is an essential nutrient and precursor to acetylcholine (a neurotransmitter involved in memory and neuromuscular function) and phosphatidylcholine (a primary structural component of cell membranes).

Adults: take 1 capsule once per day with food. Taking with food improves absorption and reduces the chance of nausea that can occur with high dose B vitamins on an empty stomach. Do not exceed the recommended dose of 1 capsule per day this formula provides vitamin B6 (as P-5-P) at 100mg, the tolerable upper intake level. A 120-capsule bottle provides a 120-day (4-month) supply at 1 capsule per day.

Do not exceed the recommended dose of 1 capsule per day. Do not combine with other supplements containing vitamin B6 without consulting a healthcare practitioner this formula already provides B6 at the tolerable upper intake level. Consult a healthcare practitioner before use if you are pregnant or breastfeeding, or if you are taking medications. Individuals sensitive to nicotinic acid may experience mild, transient skin flushing due to the inositol hexanicotinate (B3) in this formula. Keep out of reach of children.