{"product_id":"alpha-lipoic-acid-600mg-dl-ala-antioxidant-and-glucose-metabolism-120-vcaps","title":"Alpha Lipoic Acid 600mg | DL-ALA | Antioxidant and Glucose Metabolism | 120 Vcaps","description":"\u003cp\u003eEach vegan capsule delivers 600mg of DL-alpha-lipoic acid the racemic 50:50 mixture of R-ALA (naturally occurring mitochondrial enantiomer) and S-ALA (synthetic enantiomer), providing approximately 300mg of biologically active R-ALA per capsule. A universal antioxidant, antioxidant network regenerator, and essential mitochondrial enzyme cofactor.\u003c\/p\u003e\n\u003cp\u003eStop use and consult a healthcare practitioner if you experience sweating, paleness, chills, headache, dizziness, or confusion these may be symptoms of serious low blood sugar. Consult a healthcare practitioner before use if you have diabetes or are taking antidiabetic medications.\u003c\/p\u003e\n\u003ch2\u003eWhat Makes ALA a Universal Antioxidant\u003c\/h2\u003e\n\u003cp\u003eMost antioxidants operate in one environment: vitamin C works in aqueous (water-based) compartments, vitamin E works in lipid (fat-based) membranes. ALA and its reduced form DHLA are active in both simultaneously protecting water-soluble and fat-soluble cellular components with a single molecule.\u003c\/p\u003e\n\u003cp\u003eDHLA also regenerates vitamin C, vitamin E, and glutathione, extending the antioxidant activity of the entire network. This antioxidant network regeneration is the key biochemical distinction between ALA and single-environment antioxidants.\u003c\/p\u003e\n\u003ch2\u003eHow ALA Supports Glucose Metabolism\u003c\/h2\u003e\n\u003cp\u003eAt supplemental doses, free ALA activates AMPK (AMP-activated protein kinase), promoting GLUT4 glucose transporter translocation to the cell surface in muscle and adipose tissue and enhancing insulin-stimulated glucose uptake. This is the mechanism underlying the Health Canada licensed glucose metabolism claim and the mandatory caution for those with diabetes or taking antidiabetic medications.\u003c\/p\u003e\n\u003ch2\u003eALA as a Mitochondrial Enzyme Cofactor\u003c\/h2\u003e\n\u003cp\u003eEndogenously, ALA is covalently bound to two critical mitochondrial enzyme complexes: the pyruvate dehydrogenase complex (PDC), which converts pyruvate to acetyl-CoA linking glycolysis to the citric acid cycle, and the alpha-ketoglutarate dehydrogenase complex (KGDC), which catalyzes a key step within the citric acid cycle. ALA is essential for both reactions.\u003c\/p\u003e\n\u003ch2\u003eDL-ALA vs. R-ALA\u003c\/h2\u003e\n\u003cp\u003ePure R-ALA is the naturally occurring, biologically active enantiomer. DL-ALA is the racemic mixture of R-ALA and S-ALA produced by chemical synthesis. DL-ALA is more chemically stable than pure R-ALA, less prone to polymerization at room temperature, and is the form used in the majority of clinical research on alpha-lipoic acid. Each 600mg DL-ALA capsule provides approximately 300mg of R-ALA.\u003c\/p\u003e\n\u003ch2\u003eWho This Is For\u003c\/h2\u003e\n\u003cp\u003eAdults seeking a universal antioxidant active in both aqueous and lipid environments, with antioxidant network regeneration activity and glucose metabolism support. Vegan, non-GMO, and gluten free.\u003c\/p\u003e\n\u003cp\u003eConsult a healthcare practitioner before use if pregnant, breastfeeding, diabetic, or taking antidiabetic medications. Stop use if symptoms of low blood sugar occur. Keep out of reach of children.\u003c\/p\u003e","brand":"Nutridom","offers":[{"title":"Default Title","offer_id":47520879771811,"sku":"N345","price":23.7,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0623\/6589\/2771\/files\/Alpha_lipoic_acid_600_mg_DL_ALA_supplement_120_vegan_capsules.png?v=1774980094","url":"https:\/\/nutridom.ca\/products\/alpha-lipoic-acid-600mg-dl-ala-antioxidant-and-glucose-metabolism-120-vcaps","provider":"Nutridom","version":"1.0","type":"link"}