{"product_id":"ashwagandha-500mg-4-1-extract-qce-2-000mg-rasayana-rejuvenative-tonic-60-vcaps","title":"Ashwagandha 500mg | 4:1 Extract QCE 2,000mg | Rasayana Rejuvenative Tonic| 60 Vcaps","description":"\u003ch2\u003eAshwagandha 500mg | 4:1 Root Extract | QCE 2,000mg | Rasayana | 60 Vegan Capsules\u003c\/h2\u003e\n\u003cp\u003e500mg of Withania somnifera root extract (4:1, QCE 2,000mg) per vegan capsule, equivalent to 2,000mg of dried ashwagandha root. One non medicinal ingredient. Traditionally used in Ayurveda as Rasayana (Rejuvenative Tonic) and to relieve general debility, especially during convalescence or old age. Health Canada licensed NPN 80062481. Made in Canada.\u003c\/p\u003e\n\u003ch2\u003eKey Benefits\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eAshwagandha root extract 500mg per capsule\u003c\/strong\u003e Withania somnifera, root | 4:1 extract | QCE 2,000mg per capsule | QCE 4,000mg per daily dose\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eRasayana (Rejuvenative Tonic)\u003c\/strong\u003e Traditional Ayurvedic use | Health Canada licensed NPN 80062481\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eRelieves general debility, especially during convalescence or old age\u003c\/strong\u003e Licensed use NPN 80062481\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eOnly 1 non medicinal ingredient\u003c\/strong\u003e Hypromellose (vegetable capsule shell). Nothing else\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eVegan capsule\u003c\/strong\u003e Hypromellose shell, no gelatin\u003c\/li\u003e\n\u003cli\u003e\u003cstrong\u003eNon GMO | Gluten free | No artificial ingredients\u003c\/strong\u003e\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eMade in Canada\u003c\/strong\u003e GMP certified facility under Health Canada oversight\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003e60 capsules\u003c\/strong\u003e At 2 capsules per day\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2\u003eWhat This Is\u003c\/h2\u003e\n\u003cp\u003eAshwagandha 500mg provides 500mg of Withania somnifera root extract (4:1, QCE 2,000mg) per vegan capsule. At the recommended dose of 2 capsules once daily, each daily serving provides 1,000mg of extract equivalent to 4,000mg of dried ashwagandha root. One non medicinal ingredient: hypromellose vegetable capsule shell. Licensed by Health Canada with NPN 80062481 for traditional Ayurvedic use as Rasayana (Rejuvenative Tonic) and to relieve general debility, especially during convalescence or old age. Manufactured in Canada to GMP standards under the Nutridom brand.\u003c\/p\u003e\n\u003ch2\u003eThe Science\u003c\/h2\u003e\n\u003ch3\u003eWhat Is Ashwagandha?\u003c\/h3\u003e\n\u003cp\u003eWithania somnifera (Solanaceae family) is a medicinal plant native to India, North Africa, and the Mediterranean. Somnifera means sleep-inducing in Latin. Ashwagandha comes from Sanskrit: ashwa (horse) and gandha (smell), reflecting the traditional belief that it confers the strength and vitality of a horse. Also known as Indian ginseng and winter cherry. Ashwagandha has been used in Ayurvedic medicine for over 3,000 years as one of the most important Rasayana herbs, used to promote rejuvenation, vitality, and resilience.\u003c\/p\u003e\n\u003ch3\u003eRasayana and General Debility: The Licensed Uses\u003c\/h3\u003e\n\u003cp\u003eRasayana is one of the eight branches of Ayurveda, meaning path of essence: herbs used to promote rejuvenation, vitality, and resilience. General debility is a state of weakness or lack of vitality. Convalescence is the recovery period following illness, surgery, or prolonged stress. Ashwagandha has been used in Ayurvedic practice for centuries to support the body's return to strength during and after periods of depletion. These are the Health Canada licensed uses for NPN 80062481 and are the licensed, verifiable claims for this product.\u003c\/p\u003e\n\u003ch3\u003eThe Bioactive Compounds: Withanolides\u003c\/h3\u003e\n\u003cp\u003eWithanolides are the primary bioactive compounds in ashwagandha root: ergostane-type steroidal lactones unique to the Withania genus. The most studied is withaferin A. Withanolides work through two primary mechanisms relevant to the licensed uses of this formula.\u003c\/p\u003e\n\u003ch3\u003eHPA Axis Modulation\u003c\/h3\u003e\n\u003cp\u003eThe HPA (hypothalamic-pituitary-adrenal) axis is the body's primary stress response system. Chronic stress dysregulates this axis, leading to sustained elevated cortisol output. Withanolides modulate the HPA axis, supporting normalization of cortisol output. This is the primary mechanism underlying ashwagandha's Rasayana and general debility uses in Ayurvedic medicine.\u003c\/p\u003e\n\u003ch3\u003eGABA-Mimetic Activity\u003c\/h3\u003e\n\u003cp\u003eAshwagandha compounds interact with GABA-A receptors, the primary inhibitory receptors in the central nervous system. This contributes to its calming properties and is the pharmacological basis for the caution against combining ashwagandha with alcohol or sedative drugs: the effects on the central nervous system can be additive.\u003c\/p\u003e\n\u003ch3\u003eUnderstanding 4:1 Extract and QCE\u003c\/h3\u003e\n\u003cp\u003eA 4:1 extract ratio means 4 parts of dried ashwagandha root are used to produce 1 part of finished extract, concentrating the withanolides to approximately four times their concentration in dried root powder. The quantity crude equivalent (QCE) of 2,000mg is the amount of crude dried root the extract in each capsule is equivalent to, expressed as a Health Canada standardized labelling figure. The actual extract content per capsule is 500mg. At 2 capsules per day, the daily dose provides 1,000mg of extract equivalent to 4,000mg of dried ashwagandha root.\u003c\/p\u003e\n\u003ch2\u003eMedicinal Ingredient (per capsule)\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eAshwagandha (Withania somnifera, root) 500mg\u003c\/strong\u003e 4:1 extract | QCE 2,000mg | Rasayana (Rejuvenative Tonic) | Relieves general debility especially during convalescence or old age | NPN 80062481\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eNon medicinal ingredient: Hypromellose (vegetable capsule shell).\u003c\/p\u003e\n\u003ch2\u003eQuality and Trust\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eNPN 80062481\u003c\/strong\u003e Licensed by Health Canada as a Natural Health Product\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eMade in Canada\u003c\/strong\u003e GMP certified facility under Health Canada oversight\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003e4:1 root extract\u003c\/strong\u003e 500mg per capsule | QCE 2,000mg per capsule | QCE 4,000mg per daily dose\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eOnly 1 non medicinal ingredient\u003c\/strong\u003e Hypromellose vegetable capsule shell\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eVegan capsule\u003c\/strong\u003e Hypromellose shell, no gelatin\u003c\/li\u003e\n\u003cli\u003e\u003cstrong\u003eNon GMO | Gluten free | No artificial ingredients\u003c\/strong\u003e\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003e60 capsules\u003c\/strong\u003e At 2 capsules per day\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2\u003eWho This Is For\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003eAdults (not pregnant or breastfeeding) seeking a traditional Ayurvedic Rasayana (Rejuvenative Tonic) for vitality and general wellbeing from a Health Canada licensed formula\u003c\/li\u003e\n\u003cli\u003eThose experiencing general debility, fatigue, or weakness during or after illness, surgery, or prolonged stress (convalescence), consistent with the licensed use of NPN 80062481\u003c\/li\u003e\n\u003cli\u003eThose who want a single ingredient, clean label ashwagandha formula with only 1 non medicinal ingredient\u003c\/li\u003e\n\u003cli\u003eHealth conscious consumers who prefer a Health Canada licensed, GMP manufactured, vegan, Canadian made ashwagandha supplement\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2\u003eHow to Use\u003c\/h2\u003e\n\u003cp\u003eAdults: Take 2 capsules once daily. Consumption with alcohol, other drugs, or natural health products with sedative properties is not recommended. Not recommended for pregnant or breastfeeding women.\u003c\/p\u003e\n\u003ch2\u003eSafety and Cautions\u003c\/h2\u003e\n\u003cp\u003eNot recommended for pregnant or breastfeeding women. Consumption with alcohol, other drugs, or natural health products with sedative properties is not recommended. Consult a healthcare practitioner before use if you are taking medications or have a pre-existing medical condition. Keep out of reach of children. Store in a cool, dry place away from direct sunlight and moisture. Do not use if the seal is broken or missing.\u003c\/p\u003e\n\u003cp\u003eNPN 80062481. This product is not intended to diagnose, treat, cure, or prevent any disease. All health claims are consistent with Health Canada's Natural Health Products Regulations.\u003c\/p\u003e","brand":"Nutridom","offers":[{"title":"Default Title","offer_id":42910819647651,"sku":"N206","price":19.99,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0623\/6589\/2771\/files\/ASHWAGANDA.jpg?v=1772741517","url":"https:\/\/nutridom.ca\/products\/ashwagandha-500mg-4-1-extract-qce-2-000mg-rasayana-rejuvenative-tonic-60-vcaps","provider":"Nutridom","version":"1.0","type":"link"}