{"product_id":"calcium-300mg-magnesium-150mg-vitamin-d3-200iu-bone-and-teeth-support-120-softgels","title":"Calcium 300mg + Magnesium 150mg + Vitamin D3 200IU | Bone and Teeth Support | 120 Softgels","description":"\u003cp\u003eThree nutrients with distinct and interdependent roles in bone mineral metabolism in a single softgel. Calcium 300 mg (Calcium Carbonate) | Magnesium 150 mg (Magnesium Oxide) | Vitamin D3 200 IU \/ 5 mcg (Cholecalciferol). Helps in the development and maintenance of bones and teeth. Helps in the absorption and use of calcium and phosphorus.\u003cstrong\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003ch2\u003eHow the Three Nutrients Work Together\u003c\/h2\u003e\n\u003cp\u003e\u003cstrong\u003eCalcium (Calcium Carbonate) 300 mg\u003c\/strong\u003e\u003cbr\u003eCalcium is the primary structural mineral of bone and tooth tissue, comprising approximately 70% of bone mineral as hydroxyapatite. Calcium Carbonate is the most concentrated supplemental form by elemental weight (40% elemental calcium), providing 300 mg of elemental calcium per softgel. Best absorbed when taken with food, as gastric acid produced during digestion facilitates dissolution and ionization. At 2 softgels per day, this formula provides 600 mg of elemental calcium.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eVitamin D3 (Cholecalciferol) 200 IU \/ 5 mcg\u003c\/strong\u003e\u003cbr\u003eCholecalciferol is the same form of Vitamin D produced in human skin upon UV-B exposure and the preferred supplemental form for raising serum 25(OH)D levels. In the body, it is converted in the liver to 25-hydroxyvitamin D and then in the kidneys to calcitriol its active hormonal form. Calcitriol stimulates the production of calcium-binding proteins (calbindins) in the intestinal wall, increasing calcium absorption from 10–15% (without adequate Vitamin D) to 30–40% (with sufficient Vitamin D). Without adequate Vitamin D3, dietary calcium cannot be efficiently absorbed regardless of intake.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eMagnesium (Magnesium Oxide) 150 mg\u003c\/strong\u003e\u003cbr\u003eMagnesium is required for the enzymatic activation of Vitamin D specifically, the hepatic and renal hydroxylation steps that convert cholecalciferol to calcitriol. Magnesium deficiency impairs this conversion, limiting the effectiveness of both Vitamin D and calcium supplementation. Magnesium also supports the active transport of calcium into bone tissue and is itself a structural component of the bone mineral matrix, with approximately 60% of the body’s magnesium stored in bone. It is a cofactor in over 300 enzymatic reactions including ATP synthesis, protein synthesis, and DNA repair.\u003c\/p\u003e","brand":"Nutridom","offers":[{"title":"Default Title","offer_id":42910820171939,"sku":"N142","price":23.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0623\/6589\/2771\/files\/Nutridom_Liquid_Cal-Mag-Vit.D_300mg_120Vcaps.png?v=1785331006","url":"https:\/\/nutridom.ca\/products\/calcium-300mg-magnesium-150mg-vitamin-d3-200iu-bone-and-teeth-support-120-softgels","provider":"Nutridom","version":"1.0","type":"link"}