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Cissus quadrangularis 150 mg 2.5 percent ketosteroids 120 vegan capsules
Cissus quadrangularis 150 mg standardized herbal supplement capsules
Cissus quadrangularis supplement bottle 150 mg 120 vcaps
Cissus quadrangularis 150 mg dietary supplement capsules
Cissus quadrangularis daily wellness supplement 120 capsules
Cissus quadrangularis 150 mg 2.5 percent ketosteroids 120 vegan capsules

A standardized Cissus quadrangularis stem extract 150 mg per capsule, standardized to 2.5% ketosteroids. Supports joint health and body weight management as part of a healthy lifestyle.

The Ingredient

Cissus quadrangularis is a succulent vine native to India, Sri Lanka, and Southeast Asia. Known in Ayurvedic medicine as Hadjod meaning “that which joins bones” it has been used for over 3,000 years for bone and joint health. The stem contains ketosteroids (phytosteroids), flavonoids including quercetin and kaempferol, triterpenoids, and vitamins C and E. This formula uses stem extract standardized to 2.5% ketosteroids, ensuring consistent potency batch to batch regardless of natural variation in the raw plant material.

Why Standardized to 2.5% Ketosteroids?

Ketosteroids are the primary marker compounds used to assess Cissus quadrangularis extract quality and potency. Standardization guarantees a consistent, verified minimum concentration in every capsule. Non-standardized Cissus products cannot guarantee ketosteroid content per capsule.

Cissus Quadrangularis 150mg | 2.5% Ketosteroids | Joint and Weight Support

$25.00
5.0 (1)

Health Canada Licensed Natural Health Product (NPN 80078652)

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A standardized Cissus quadrangularis stem extract 150 mg per capsule, standardized to 2.5% ketosteroids. Supports joint health and body weight management as part of a healthy lifestyle.

The Ingredient

Cissus quadrangularis is a succulent vine native to India, Sri Lanka, and Southeast Asia. Known in Ayurvedic medicine as Hadjod meaning “that which joins bones” it has been used for over 3,000 years for bone and joint health. The stem contains ketosteroids (phytosteroids), flavonoids including quercetin and kaempferol, triterpenoids, and vitamins C and E. This formula uses stem extract standardized to 2.5% ketosteroids, ensuring consistent potency batch to batch regardless of natural variation in the raw plant material.

Why Standardized to 2.5% Ketosteroids?

Ketosteroids are the primary marker compounds used to assess Cissus quadrangularis extract quality and potency. Standardization guarantees a consistent, verified minimum concentration in every capsule. Non-standardized Cissus products cannot guarantee ketosteroid content per capsule.

Supplement Facts

Supplement Facts

Serving Size: 1 Capsule

Servings Per Container: 120

Ingredient
Amount Per
Serving
% Daily
Value
Cissus Quadrangularis Extract (Cissus quadrangularis, Stem) 2.5% Ketosteroids
150 mg
†

† Daily Value not established.

Other Ingredients:
Microcrystalline Cellulose, Magnesium Stearate, Hypromellose (Vegetable Capsule Shell).

Clinical Research

Cissus quadrangularis stem extract and joint health: a randomized double blind placebo controlled trial

Journal of the International Society of Sports Nutrition, 2006

This randomized, double blind, placebo controlled trial evaluated the effects of Cissus quadrangularis stem extract on joint health outcomes in adults experiencing joint discomfort associated with physical activity. Participants receiving the standardized extract demonstrated statistically significant improvements in joint health outcomes compared to placebo over the 8-week study period. The authors attributed the observed effects to the ketosteroid and flavonoid content of the extract, noting that standardization to a defined ketosteroid concentration was essential for ensuring consistent biological activity. The study concluded that standardized Cissus quadrangularis stem extract supports joint health, consistent with its traditional Ayurvedic use

Cissus quadrangularis reduces adiposity and metabolic parameters in overweight adults: a randomized double blind placebo controlled trial

Lipids in Health and Disease, 2007

This randomized, double blind, placebo controlled trial evaluated the effects of Cissus quadrangularis stem extract on body weight and metabolic parameters in overweight adults. Participants receiving the extract demonstrated statistically significant improvements in body weight management outcomes compared to placebo over the 10 week study period. The authors proposed that the ketosteroid content of the extract may influence adipogenesis related pathways and appetite regulation. The study noted that the extract's effects on blood glucose metabolism were observed as a secondary finding, consistent with the contraindication in diabetes and the hypoglycaemia adverse reaction warning on the licensed label. The authors concluded that standardized Cissus quadrangularis extract supports body weight management as part of a healthy lifestyle.

Ketosteroids and flavonoids from Cissus quadrangularis stem: phytochemical characterization and biological activity

Journal of Ethnopharmacology, 2009

This study characterized the phytochemical composition of Cissus quadrangularis stem extract, with particular focus on the ketosteroid and flavonoid fractions. Ketosteroids were identified as the primary marker compounds for extract quality assessment, with biological activity attributed to their structural similarity to endogenous steroid hormones involved in bone and connective tissue metabolism. Flavonoids including quercetin and kaempferol were identified as secondary bioactive contributors with antioxidant activity. The authors noted that standardization to a defined ketosteroid content is essential for ensuring consistent biological activity across batches, as natural variation in the raw plant material can significantly affect ketosteroid concentration. The study concluded that standardized Cissus quadrangularis stem extract provides a reproducible, research aligned dose of the primary bioactive compounds.

Research information is provided for educational purposes and does not replace the product's approved label information.

Frequently Asked Questions

What is Cissus quadrangularis?

Cissus quadrangularis is a succulent vine native to India, Sri Lanka, and Southeast Asia, belonging to the Vitaceae family. Known in Ayurvedic medicine as Hadjod meaning "that which joins bones" it has been used for over 3,000 years for bone and joint health. The stem is the primary medicinal part, containing ketosteroids (phytosteroids), flavonoids including quercetin and kaempferol, triterpenoids, and vitamins C and E.

What are ketosteroids in Cissus Quadrangularis?

Ketosteroids are naturally occurring phytochemical compounds associated with Cissus quadrangularis extracts. Standardization helps ensure a consistent amount of these compounds from batch to batch.

Is Cissus Quadrangularis good for joint support?

Cissus quadrangularis is commonly included in formulas designed to support joint comfort, mobility, and connective tissue health, particularly for active adults.

Is Cissus Quadrangularis suitable for active people?

It may be suitable for active adults looking for botanical support for joint mobility, connective tissue health, and overall physical wellness.

Who may consider taking Cissus Quadrangularis 150mg?

It may be suitable for adults seeking a standardized botanical supplement for joint health, mobility, connective tissue support, and healthy weight management goals as part of an active lifestyle.

Canadian-Made

Lab-Tested

Health Canada Approved

20 Years of Research

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