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Curcumin 400mg | 95% Curcuminoids | Antioxidant | 60 Vcaps
Curcumin 400mg | 95% Curcuminoids | Antioxidant | 60 Vcaps LABEL
Curcumin 400mg | 95% Curcuminoids | Antioxidant | 60 Vcaps

Curcumin is the main active compound found in turmeric root (Curcuma longa) one of the most studied natural ingredients in the world with over 3,000 published research papers. Each capsule delivers 400mg of curcumin from turmeric root, concentrated to 95% curcuminoids the same grade used in most clinical studies, and roughly 19 to 47 times stronger than raw turmeric powder.

What Are Curcuminoids?

Curcuminoids are the natural compounds in turmeric that give it its golden colour and most of its health benefits. There are three of them: curcumin (the most abundant, making up about 75–80%), demethoxycurcumin (about 15–20%), and bisdemethoxycurcumin (about 3–5%). Raw turmeric root only contains about 2–5% curcuminoids by weight (Tayyem et al., Nutrition and Cancer, 2006). A 95% standardized extract is far more concentrated meaning you get a consistent, meaningful dose of the active compounds in every single capsule, not the trace amounts found in cooking turmeric.

How It Works as an Antioxidant

Curcumin helps protect your cells from damage caused by free radicals unstable molecules that build up from everyday stress, pollution, and normal body processes. It does this in two main ways: by directly neutralizing free radicals, and by activating a built in cellular defence system (called the Nrf2 pathway) that boosts your body’s own antioxidant enzymes including superoxide dismutase, catalase, and glutathione peroxidase (Ak & Gülcüin, Chemistry & Biology Interactions, 2008).

How It Helps with Joint Inflammation

Curcumin is one of the most studied natural compounds for inflammation. It works by calming a key inflammation switch in the body called NF-κB, which controls the production of inflammatory signals like TNF-α, IL-1β, IL-6, and COX-2 (Aggarwal & Harikumar, International Journal of Biochemistry & Cell Biology, 2009). In plain terms: it helps dial down the inflammatory response at the source. A review of multiple clinical trials found that curcumin supplementation meaningfully reduced joint pain and inflammation scores compared to placebo (Daily et al., Journal of Medicinal Food, 2016).

Curcumin 400mg | 95% Curcuminoids | Antioxidant & Joint Inflammation

$24.50
5.0 (1)

Health Canada Licensed Natural Health Product (NPN 80040403)

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Curcumin is the main active compound found in turmeric root (Curcuma longa) one of the most studied natural ingredients in the world with over 3,000 published research papers. Each capsule delivers 400mg of curcumin from turmeric root, concentrated to 95% curcuminoids the same grade used in most clinical studies, and roughly 19 to 47 times stronger than raw turmeric powder.

What Are Curcuminoids?

Curcuminoids are the natural compounds in turmeric that give it its golden colour and most of its health benefits. There are three of them: curcumin (the most abundant, making up about 75–80%), demethoxycurcumin (about 15–20%), and bisdemethoxycurcumin (about 3–5%). Raw turmeric root only contains about 2–5% curcuminoids by weight (Tayyem et al., Nutrition and Cancer, 2006). A 95% standardized extract is far more concentrated meaning you get a consistent, meaningful dose of the active compounds in every single capsule, not the trace amounts found in cooking turmeric.

How It Works as an Antioxidant

Curcumin helps protect your cells from damage caused by free radicals unstable molecules that build up from everyday stress, pollution, and normal body processes. It does this in two main ways: by directly neutralizing free radicals, and by activating a built in cellular defence system (called the Nrf2 pathway) that boosts your body’s own antioxidant enzymes including superoxide dismutase, catalase, and glutathione peroxidase (Ak & Gülcüin, Chemistry & Biology Interactions, 2008).

How It Helps with Joint Inflammation

Curcumin is one of the most studied natural compounds for inflammation. It works by calming a key inflammation switch in the body called NF-κB, which controls the production of inflammatory signals like TNF-α, IL-1β, IL-6, and COX-2 (Aggarwal & Harikumar, International Journal of Biochemistry & Cell Biology, 2009). In plain terms: it helps dial down the inflammatory response at the source. A review of multiple clinical trials found that curcumin supplementation meaningfully reduced joint pain and inflammation scores compared to placebo (Daily et al., Journal of Medicinal Food, 2016).

Supplement Facts

Supplement Facts

Serving Size: 1 Capsule

Servings Per Container: 60

Ingredient
Amount Per
Serving
% Daily
Value
Curcumin (Curcuma longa, Root) Standardized to 95% Curcuminoids
400 mg
*

† Daily Value not established

Other Ingredients:
Microcrystalline Cellulose, Hypromellose (Capsule Shell).

Clinical Research

Efficacy of turmeric extracts and curcumin for alleviating the symptoms of joint arthritis: a systematic review and meta analysis of randomized clinical trials

Journal of Medicinal Food, 2016 (Daily et al.)

This systematic review and meta analysis examined randomized controlled trials evaluating curcumin and turmeric extract supplementation on joint pain, stiffness, and physical function in adults with joint inflammation and arthritis. Eight RCTs were included in the analysis. Curcumin supplementation was associated with statistically significant reductions in pain scores and improvements in physical function compared to placebo across multiple trials. The effect sizes were clinically meaningful, with several trials demonstrating reductions in pain and stiffness comparable to anti inflammatory reference comparators. The authors concluded that curcumin and turmeric extracts are effective and safe for relieving symptoms of joint arthritis, and recommended further large-scale trials to establish optimal dosing protocols.

Molecular targets of curcumin for cancer prevention and therapy: mechanisms of action

International Journal of Biochemistry & Cell Biology, 2009 (Aggarwal & Harikumar)

This landmark mechanistic review by Aggarwal and Harikumar among the most cited papers in curcumin research examined curcumin's interactions with multiple molecular targets relevant to inflammation. The review documented curcumin's inhibition of NF-κB (Nuclear Factor kappa B), the master transcription factor that regulates the expression of pro inflammatory cytokines including TNF-α, IL-1β, IL-6, and the enzyme COX-2. By blocking NF-κB activation, curcumin reduces the downstream production of these inflammatory mediators at the gene expression level. The review also documented curcumin's modulation of AP-1, STAT3, and MAPK signalling pathways all involved in inflammatory cascades. These molecular mechanisms provide the mechanistic basis for curcumin's documented anti-inflammatory activity in joint tissue

Antioxidant and radical scavenging properties of curcumin

Chemistry & Biological Interactions, 2008 (Ak & Gülçin)

This study examined the direct free radical scavenging and antioxidant enzyme activating mechanisms of curcumin across multiple in vitro assay systems. Curcumin demonstrated potent scavenging activity against multiple reactive oxygen species (ROS) and reactive nitrogen species (RNS), including superoxide anion, hydrogen peroxide, hydroxyl radical, and nitric oxide. The study also documented curcumin's activation of the Nrf2/ARE (Nuclear factor erythroid 2-related factor 2 / antioxidant response element) pathway the primary cellular defence mechanism governing endogenous antioxidant enzyme expression, including superoxide dismutase (SOD), catalase, and glutathione peroxidase. The authors concluded that curcumin is a highly potent, multi mechanism antioxidant compound, operating through both direct free radical scavenging and indirect upregulation of endogenous antioxidant defences.

Research information is provided for educational purposes and does not replace the product's approved label information.

Frequently Asked Questions

What is curcumin and how is it different from turmeric?

Turmeric is the whole spice the dried, ground root of Curcuma longa, a plant in the ginger family native to South and Southeast Asia. Curcumin is the primary active compound within turmeric, belonging to a family of polyphenolic pigments called curcuminoids. The problem with eating turmeric as a spice or taking a basic turmeric powder supplement is concentration: raw turmeric root contains only 2–5% curcuminoids by weight. That means the vast majority of what you're consuming is starch and fibre not the bioactive compound that research actually studies. This formula provides 400mg of curcumin per capsule from Curcuma longa root, standardized to 95% curcuminoids roughly 19 to 47 times more concentrated than raw turmeric root

What are curcuminoids?

Curcuminoids are naturally occurring compounds found in turmeric. They are responsible for much of turmeric’s characteristic yellow colour and are widely studied for their antioxidant and joint supporting properties.

Is Curcumin good for joint inflammation?

Curcumin is commonly used in joint health supplements because it may help support a healthy inflammatory response, joint comfort, and mobility.

How does Curcumin support joint health?

Curcuminoids provide antioxidant activity and may help support the body’s normal inflammatory processes, making curcumin a popular supplement for joint comfort and flexibility.

What is the difference between Curcumin and Turmeric?

Turmeric is the whole botanical, while curcumin is one of its main active compounds. A 95% curcuminoid extract is considerably more concentrated than ordinary turmeric powder.

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20 Years of Research

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