USA CUSTOMERS — SHOP DUTY FREE

FREE SHIPPING OVER $55

GET 10% OFF FIRST ORDER

Your cart

Your cart is empty

Continue shopping
L-Arginine 1000 mg nitric oxide support supplement 120 tablets
L-Arginine 1000 mg circulation support formula 120 tablets
L-Arginine 1000 mg supplement bottle 120 tablets
L-Arginine 1000 mg daily wellness supplement 120 count
L-Arginine nitric oxide support tablets 1000 mg
L-Arginine 1000 mg supplement facts label nitric oxide formula
L-Arginine 1000 mg nitric oxide support supplement 120 tablets

L-Arginine 1000mg | Nitric Oxide and Circulation Support | 120 Tablets

Each tablet delivers 1000mg of free form L-arginine HCl, a semi-essential amino acid and the direct substrate for nitric oxide synthase (NOS), the enzyme that produces nitric oxide in the body. Nitric oxide is a potent vasodilator that relaxes vascular smooth muscle, supporting healthy blood vessel tone and circulation. Supports nitric oxide production, healthy circulation, and exercise performance.

Who This Is For

  • Adults seeking nitric oxide and circulation support from a high-dose free form L-arginine supplement
  • Athletes and active adults wanting to support blood flow and oxygen delivery to working muscles during exercise
  • Those seeking cardiovascular wellness support through nitric oxide production
  • Those wanting a clean, vegan, non-GMO amino acid supplement with no artificial additives
  • Those seeking a Canadian made supplement

Where Does L-Arginine Come From?

L-arginine is a semi-essential amino acid found naturally in protein-containing foods including meat, poultry, fish, dairy, nuts, and legumes. L-arginine used in supplements is produced by fermentation of plant-based substrates, yielding a compound chemically identical to the L-arginine found in dietary protein. Free form means the amino acid is not bound to a protein chain and is available for direct absorption. This product is formulated and manufactured entirely in Canada.

How Does L-Arginine Support Nitric Oxide and Circulation?

L-arginine is the direct substrate for nitric oxide synthase (NOS) enzymes, which convert L-arginine and oxygen to nitric oxide (NO) and L-citrulline. Nitric oxide is a gaseous signaling molecule that acts as a potent vasodilator by relaxing vascular smooth muscle, reducing vascular resistance, and supporting healthy blood vessel tone and circulation. Endothelial nitric oxide synthase (eNOS), the primary NOS enzyme in blood vessel walls, uses L-arginine to produce NO that regulates local blood flow and vascular function. By providing L-arginine as substrate, supplementation supports the body's nitric oxide production pathway and healthy circulation.

L-Arginine 1000mg | Nitric Oxide and Circulation Support | 120 Tablets

$26.99

Health Canada Licensed Natural Health Product (NPN 80139240)

Auto-renews, skip or cancel anytime.

To add to cart, go to the product page and select a purchase option
Shipping calculated at checkout.

L-Arginine 1000mg | Nitric Oxide and Circulation Support | 120 Tablets

Each tablet delivers 1000mg of free form L-arginine HCl, a semi-essential amino acid and the direct substrate for nitric oxide synthase (NOS), the enzyme that produces nitric oxide in the body. Nitric oxide is a potent vasodilator that relaxes vascular smooth muscle, supporting healthy blood vessel tone and circulation. Supports nitric oxide production, healthy circulation, and exercise performance.

Who This Is For

  • Adults seeking nitric oxide and circulation support from a high-dose free form L-arginine supplement
  • Athletes and active adults wanting to support blood flow and oxygen delivery to working muscles during exercise
  • Those seeking cardiovascular wellness support through nitric oxide production
  • Those wanting a clean, vegan, non-GMO amino acid supplement with no artificial additives
  • Those seeking a Canadian made supplement

Where Does L-Arginine Come From?

L-arginine is a semi-essential amino acid found naturally in protein-containing foods including meat, poultry, fish, dairy, nuts, and legumes. L-arginine used in supplements is produced by fermentation of plant-based substrates, yielding a compound chemically identical to the L-arginine found in dietary protein. Free form means the amino acid is not bound to a protein chain and is available for direct absorption. This product is formulated and manufactured entirely in Canada.

How Does L-Arginine Support Nitric Oxide and Circulation?

L-arginine is the direct substrate for nitric oxide synthase (NOS) enzymes, which convert L-arginine and oxygen to nitric oxide (NO) and L-citrulline. Nitric oxide is a gaseous signaling molecule that acts as a potent vasodilator by relaxing vascular smooth muscle, reducing vascular resistance, and supporting healthy blood vessel tone and circulation. Endothelial nitric oxide synthase (eNOS), the primary NOS enzyme in blood vessel walls, uses L-arginine to produce NO that regulates local blood flow and vascular function. By providing L-arginine as substrate, supplementation supports the body's nitric oxide production pathway and healthy circulation.

Supplement Facts

Supplement Facts

Serving Size: 1 Tablet

Servings Per Container: 120

Ingredient
Amount Per
Serving
% Daily
Value
L-Arginine (L-Arginine Monohydrochloride)
1,000 mg
†

† Daily Value not established

Other Ingredients:
Hypromellose, Croscarmellose Sodium, Microcrystalline Cellulose, Stearic Acid, Silica

Clinical Research

L-arginine and nitric oxide: a review of the clinical evidence for cardiovascular health

Cardiovascular Drug Reviews, 2007

This comprehensive review examined the clinical evidence for L-arginine supplementation and nitric oxide production in cardiovascular health. The review confirmed that L-arginine is the direct substrate for endothelial nitric oxide synthase (eNOS) and that supplemental L-arginine supports nitric oxide production, endothelial function, and healthy vascular tone. The authors documented evidence for L-arginine's effects on blood flow, vascular resistance, and exercise capacity across multiple clinical studies, and concluded that L-arginine supplementation supports cardiovascular wellness through nitric oxide mediated vasodilation.

Oral L-arginine supplementation improves endothelial function and reduces markers of inflammation in healthy adults

Journal of Nutrition, 2003

This randomized controlled trial administered oral L-arginine supplementation to healthy adults and measured endothelial function, nitric oxide bioavailability, and vascular health markers. The study found that L-arginine supplementation significantly improved endothelial function (measured by flow-mediated dilation) and increased nitric oxide bioavailability compared to placebo. The authors concluded that oral L-arginine supplementation supports endothelial nitric oxide production and healthy vascular function in adults.

Effects of L-arginine supplementation on exercise metabolism

Current Opinion in Clinical Nutrition and Metabolic Care, 2010

This review examined the effects of L-arginine supplementation on exercise performance and muscle blood flow. The review found that L-arginine supplementation supports nitric oxide-mediated vasodilation during exercise, increasing blood flow and oxygen delivery to working muscles. The authors documented evidence for L-arginine's role in supporting exercise capacity and muscle performance through enhanced circulation, and confirmed that pre-exercise timing (30–60 minutes before activity) optimizes the nitric oxide response during exercise.

Research information is provided for educational purposes and does not replace the product's approved label information.

Frequently Asked Questions

What is L-arginine and what is it used for?

L-arginine is a semi-essential amino acid and the direct substrate for nitric oxide synthase (NOS) the enzyme that produces nitric oxide in the body. Nitric oxide is a potent vasodilator that relaxes vascular smooth muscle, supporting healthy blood vessel tone and circulation. L-arginine supplementation supports nitric oxide production, healthy circulation, and exercise performance. Consult a healthcare practitioner before use if you are taking medications for cardiovascular conditions, blood pressure, or erectile dysfunction, or if you are pregnant or breastfeeding.

How does L-arginine produce nitric oxide?

L-arginine is converted to nitric oxide (NO) and L-citrulline by nitric oxide synthase (NOS) enzymes, using oxygen as a co-substrate. Endothelial nitric oxide synthase (eNOS) the primary NOS enzyme in blood vessel walls uses L-arginine to produce NO that regulates local blood flow and vascular function. Nitric oxide acts as a gaseous signaling molecule that relaxes vascular smooth muscle, reduces vascular resistance, and supports healthy blood vessel tone and circulation. By providing L-arginine as substrate, supplementation supports the body's endogenous nitric oxide production pathway.

What does free form L-arginine HCl mean?

Free form means the amino acid is not bound to a protein chain and is available for direct absorption in the small intestine no digestion of a protein is required before absorption. L-arginine HCl (monohydrochloride) is the hydrochloride salt form of L-arginine, which provides stability and consistent potency. Free form L-arginine HCl is the pharmaceutical-grade form used in clinical research and supplement formulation, produced by fermentation of plant-based substrates.

Can L-arginine support exercise performance?

L-arginine supports exercise performance through nitric oxide mediated vasodilation increased blood flow to working muscles supports oxygen and nutrient delivery during exercise and waste product removal during recovery. L-arginine is commonly used as a pre workout supplement for this reason. Consult a healthcare practitioner before use if you have a cardiovascular condition and are attempting an increase in physical activity.

Who should not take L-arginine?

Do not use L-arginine if you have an active herpes simplex virus infection L-arginine may promote viral replication. Consult a healthcare practitioner before use if you are taking medications for cardiovascular conditions, blood pressure, or erectile dysfunction, or if you are pregnant or breastfeeding. High doses may cause gastrointestinal discomfort in some individuals. Keep out of reach of children.

Can L-arginine be taken with blood pressure medications?

Consult a healthcare practitioner before use if you are taking blood pressure medications. L-arginine supports nitric oxide production and vasodilation, which may have additive blood pressure lowering effects when combined with antihypertensive medications. Do not self supplement with L-arginine if you are on blood pressure medications without professional guidance and monitoring.

Canadian-Made

Lab-Tested

Health Canada Approved

20 Years of Research

Related Product

Recently viewed