{"product_id":"l-citrulline-750mg-circulation-and-nitric-oxide-support-free-form-amino-acid-120-vcaps","title":"L-Citrulline 750mg | Circulation and Nitric Oxide Support | Free Form Amino Acid | 120 Vcaps","description":"\u003ch2\u003eL-Citrulline 750mg | Circulation and Nitric Oxide Support | Free Form Amino Acid | 120 Vcaps\u003c\/h2\u003e\n\u003cp\u003eEach capsule delivers 750mg of pure free form L-citrulline, a non-essential amino acid that serves as a precursor to L-arginine and nitric oxide in the body. L-citrulline is absorbed intact from the gastrointestinal tract and converted to L-arginine in the kidneys, supporting sustained L-arginine availability and nitric oxide production. Supports healthy circulation and exercise performance as part of a balanced diet and active lifestyle. \u003c\/p\u003e\n\u003ch2\u003eWho This Is For\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003eAthletes and active adults seeking circulation and exercise performance support from a Health Canada licensed free form L-citrulline supplement\u003c\/li\u003e\n\u003cli\u003eThose who prefer L-citrulline over L-arginine for its superior bioavailability and more sustained plasma L-arginine elevation\u003c\/li\u003e\n\u003cli\u003eThose wanting a clean, vegan, non-GMO amino acid supplement with no artificial additives\u003c\/li\u003e\n\u003cli\u003eThose seeking a Canadian made supplement with full Health Canada licensing\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2\u003eWhere Does L-Citrulline Come From?\u003c\/h2\u003e\n\u003cp\u003eL-citrulline was first isolated from watermelon (Citrullus vulgaris) in 1930, which remains one of the richest natural food sources of L-citrulline. L-citrulline used in supplements is synthetically produced by fermentation or chemical synthesis, yielding a compound chemically identical to the L-citrulline found naturally in watermelon and other foods. \u003c\/p\u003e\n\u003ch2\u003eWhy Is L-Citrulline Better Than L-Arginine for Nitric Oxide Support?\u003c\/h2\u003e\n\u003cp\u003eL-arginine is the direct substrate for nitric oxide synthase (NOS), the enzyme that produces nitric oxide. However, oral L-arginine supplementation is limited by significant first-pass metabolism in the intestinal wall and liver, where the enzyme arginase rapidly degrades L-arginine before it reaches systemic circulation. L-citrulline bypasses this limitation entirely because it is not a substrate for arginase. It is absorbed intact and converted to L-arginine in the kidneys, where it enters systemic circulation. Research comparing oral L-citrulline to oral L-arginine consistently shows that L-citrulline produces greater and more sustained increases in plasma L-arginine levels than equivalent doses of L-arginine itself. This is why L-citrulline is the preferred form for nitric oxide and circulation support.\u003c\/p\u003e\n\u003ch2\u003eKey Benefits\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eCirculation support\u003c\/strong\u003e L-citrulline supports the L-citrulline to L-arginine to nitric oxide pathway. Nitric oxide is a potent vasodilator that relaxes vascular smooth muscle, supporting healthy blood vessel tone and circulation. Health Canada licensed use under NPN 80139498.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eExercise performance support\u003c\/strong\u003e Supports nitric oxide production and healthy circulation to working muscles during exercise. Also supports urea cycle function and ammonia clearance, a key contributor to exercise-induced fatigue. Health Canada licensed use under NPN 80139498.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eSuperior bioavailability vs. L-arginine\u003c\/strong\u003e Bypasses first-pass arginase metabolism. Greater and more sustained plasma L-arginine elevation than equivalent oral L-arginine doses.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003e750mg free form L-citrulline per capsule\u003c\/strong\u003e 3000mg per daily dose of 4 capsules (2 capsules twice daily).\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eHealth Canada licensed\u003c\/strong\u003e NPN 80139498. Made in Canada.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eVegan and non-GMO\u003c\/strong\u003e Gluten free, soy free. Hypromellose vegan capsule, no gelatin.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003e120 capsules\u003c\/strong\u003e 30 day supply at 4 capsules per day.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2\u003eMedicinal Ingredients (per capsule)\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cstrong\u003eL-Citrulline (free form) 750mg\u003c\/strong\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eNon-medicinal ingredients: Hypromellose (vegetable capsule shell), microcrystalline cellulose, magnesium stearate. Non-GMO, gluten free, soy free. No artificial colours, flavours, sweeteners, or preservatives.\u003c\/p\u003e\n\u003ch2\u003eQuality and Trust\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eNPN 80139498\u003c\/strong\u003e Licensed by Health Canada as a Natural Health Product\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eMade in Canada\u003c\/strong\u003e Quality controlled facility under federal oversight\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003ePure free form L-citrulline\u003c\/strong\u003e Pharmaceutical grade purity. Synthetically produced for consistent potency.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eVegan capsule\u003c\/strong\u003e Hypromellose, no gelatin or animal-derived ingredients\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eNon-GMO, gluten free, soy free\u003c\/strong\u003e No artificial colours, flavours, sweeteners, or preservatives\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003e120 capsules\u003c\/strong\u003e 30 day supply at 4 capsules per day\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2\u003eHow to Take L-Citrulline\u003c\/h2\u003e\n\u003cp\u003eAdults: Take 2 capsules 2 times per day, with or without food. Commonly taken before exercise for circulation and performance support. At 4 capsules per day, one bottle of 120 capsules provides a 30 day supply.\u003c\/p\u003e\n\u003ch2\u003eStorage\u003c\/h2\u003e\n\u003cp\u003eStore in a cool, dry place away from direct sunlight and moisture. Keep the bottle tightly sealed after each use. Do not use if the seal is broken or missing. Keep out of reach of children.\u003c\/p\u003e\n\u003ch2\u003eSafety and Cautions\u003c\/h2\u003e\n\u003cp\u003eAsk a healthcare practitioner before use if you are taking medication for cardiovascular diseases, erectile dysfunction, or blood thinners. Ask a healthcare practitioner before use if you have a cardiovascular disease and are attempting an increase in physical activity. Ask a healthcare practitioner before use if you are pregnant or breastfeeding. Keep out of reach of children.\u003c\/p\u003e\n\u003cp\u003eNPN 80139498. All health claims are consistent with Health Canada's Natural Health Products Regulations.\u003c\/p\u003e","brand":"Nutridom","offers":[{"title":"Default Title","offer_id":46325411610787,"sku":"N331","price":24.99,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0623\/6589\/2771\/files\/Nutridom_L_Citrulline_750_mg_120_Vegan_Capsules_Amino_Acid_Supplement.png?v=1772742460","url":"https:\/\/nutridom.ca\/products\/l-citrulline-750mg-circulation-and-nitric-oxide-support-free-form-amino-acid-120-vcaps","provider":"Nutridom","version":"1.0","type":"link"}