{"product_id":"l-citrulline-750mg-circulation-and-nitric-oxide-support-free-form-amino-acid","title":"L-Citrulline 750mg | Circulation and Nitric Oxide Support | Free Form Amino Acid","description":"\u003cp\u003eEach capsule delivers 750mg of pure free form L-citrulline, a non-essential amino acid that serves as a precursor to L-arginine and nitric oxide in the body. L-citrulline is absorbed intact from the gastrointestinal tract and converted to L-arginine in the kidneys, supporting sustained L-arginine availability and nitric oxide production. Supports healthy circulation and exercise performance as part of a balanced diet and active lifestyle. \u003c\/p\u003e\n\u003ch2\u003eWho This Is For\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003eAthletes and active adults seeking circulation and exercise performance support from a Health Canada licensed free form L-citrulline supplement\u003c\/li\u003e\n\u003cli\u003eThose who prefer L-citrulline over L-arginine for its superior bioavailability and more sustained plasma L-arginine elevation\u003c\/li\u003e\n\u003cli\u003eThose wanting a clean, vegan, non-GMO amino acid supplement with no artificial additives\u003c\/li\u003e\n\u003cli\u003eThose seeking a Canadian made supplement with full Health Canada licensing\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2\u003eWhere Does L-Citrulline Come From?\u003c\/h2\u003e\n\u003cp\u003eL-citrulline was first isolated from watermelon (Citrullus vulgaris) in 1930, which remains one of the richest natural food sources of L-citrulline. L-citrulline used in supplements is synthetically produced by fermentation or chemical synthesis, yielding a compound chemically identical to the L-citrulline found naturally in watermelon and other foods. \u003c\/p\u003e\n\u003ch2\u003eWhy Is L-Citrulline Better Than L-Arginine for Nitric Oxide Support?\u003c\/h2\u003e\n\u003cp\u003eL-arginine is the direct substrate for nitric oxide synthase (NOS), the enzyme that produces nitric oxide. However, oral L-arginine supplementation is limited by significant first-pass metabolism in the intestinal wall and liver, where the enzyme arginase rapidly degrades L-arginine before it reaches systemic circulation. L-citrulline bypasses this limitation entirely because it is not a substrate for arginase. It is absorbed intact and converted to L-arginine in the kidneys, where it enters systemic circulation. Research comparing oral L-citrulline to oral L-arginine consistently shows that L-citrulline produces greater and more sustained increases in plasma L-arginine levels than equivalent doses of L-arginine itself. This is why L-citrulline is the preferred form for nitric oxide and circulation support.\u003c\/p\u003e","brand":"Nutridom","offers":[{"title":"Default Title","offer_id":46325411610787,"sku":"N331","price":23.99,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0623\/6589\/2771\/files\/Nutridom_L_Citrulline_750_mg_120_Vegan_Capsules_Amino_Acid_Supplement.png?v=1772742460","url":"https:\/\/nutridom.ca\/products\/l-citrulline-750mg-circulation-and-nitric-oxide-support-free-form-amino-acid","provider":"Nutridom","version":"1.0","type":"link"}