Lion’s Mane 5500mg QCE | 40% Polysaccharides | Cognition & Immune Support | 180 Vcaps

5500mg QCE (Quiescent Extraction equivalent) of Lion’s Mane (Hericium erinaceus) fruiting body extract per vegetable capsule a 10:1 concentrated extract standardized to 40% polysaccharides. Cognitive health and immune function support.

Key Features

• 5500mg QCE per capsule 10:1 Lion’s Mane fruiting body extract. Concentrated equivalent of 5500mg raw fruiting body.
• Standardized to 40% polysaccharides Consistent bioactive content per capsule.
• Hericium erinaceus fruiting body Premium fruiting body source. Not mycelium on grain.
• Health Canada licensed NPN 80144496 Made in Canada.
• Vegan capsule Vegetable capsule shell.
• 180 vcaps

Recommended Use

Adults: As directed by a healthcare practitioner. Consult a healthcare practitioner before use if you are pregnant or breastfeeding, have a medical condition, or are taking medications.

Lion’s Mane: Hericenones, Erinacines, and the NGF Pathway

Lion’s Mane (Hericium erinaceus) is a medicinal mushroom with a distinctive biology among functional fungi. It is the only known mushroom to contain two classes of neuroactive compounds unique to this species: hericenones (found in the fruiting body) and erinacines (found in the mycelium). Both compound classes have been studied for their ability to stimulate the synthesis of Nerve Growth Factor (NGF) a neurotrophin essential for the growth, maintenance, and survival of neurons in the central and peripheral nervous system.

NGF binds to TrkA (tropomyosin receptor kinase A) receptors on neurons, activating intracellular signalling cascades that support neuronal differentiation, synaptic plasticity, and the maintenance of cholinergic neurons in the basal forebrain a population of neurons critically involved in learning, memory, and cognitive function. NGF itself does not cross the blood-brain barrier, but hericenones and erinacines are small lipophilic molecules that can cross the BBB and stimulate endogenous NGF synthesis within the brain.

This formula uses Hericium erinaceus fruiting body the above ground reproductive structure of the mushroom standardized to 40% polysaccharides. Fungal polysaccharides, primarily beta-glucans, are the primary immunomodulatory compounds in medicinal mushrooms. Beta-glucans interact with pattern recognition receptors (particularly Dectin-1 and TLR2) on immune cells including macrophages, dendritic cells, and NK cells, supporting normal immune function through innate immune pathway activation.

Fruiting Body vs Mycelium: Why It Matters

Lion’s Mane supplements vary significantly in their source material. Fruiting body extracts are derived from the actual mushroom the structure that accumulates the highest concentrations of hericenones and beta-glucan polysaccharides. Mycelium-on-grain products are produced by growing mycelium on a grain substrate (typically rice or oats); the final product contains significant amounts of undigested grain starch alongside the mycelium, diluting the active mushroom content. This formula uses Hericium erinaceus fruiting body, providing a concentrated, standardized source of Lion’s Mane bioactives without grain dilution.

Who This Is For

• Adults seeking a high-potency, standardized Lion’s Mane fruiting body extract for daily cognitive health and immune function support
• Those who want a Health Canada licensed, 40% polysaccharide standardized Hericium erinaceus supplement in a vegan, Canadian made formula
• Those who prefer fruiting body over mycelium-on-grain for a concentrated, grain-free Lion’s Mane extract

Consult a healthcare practitioner before use if you are pregnant or breastfeeding, have a medical condition, or are taking medications. Keep out of reach of children.

Medicinal Ingredient (per capsule)

• Lion’s Mane (Hericium erinaceus, fruiting body) 550mg 10:1 extract. QCE 5500mg. Standardized to 40% polysaccharides. NPN 80144496.

Non-medicinal ingredients: Vegetable capsule shell. Vegan. Made in Canada.

Quality and Trust

• NPN 80144496 Licensed by Health Canada as a Natural Health Product
• Made in Canada
• 5500mg QCE per capsule 10:1 Hericium erinaceus fruiting body extract
• Standardized to 40% polysaccharides Consistent bioactive content
• Fruiting body source Not mycelium on grain
• Vegan capsule Vegetable capsule shell
• 180 vcaps

Storage

Store in a cool, dry place away from direct sunlight and moisture. Keep the bottle tightly sealed after each use. Do not use if the seal is broken or missing. Keep out of reach of children.

Cautions

Consult a healthcare practitioner before use if you are pregnant or breastfeeding, have a medical condition, or are taking medications. Keep out of reach of children.

NPN 80144496.