{"product_id":"magnesium-bisglycinate-200mg-elemental-chelated-120-vcaps","title":"Magnesium Bisglycinate 200mg Elemental | Chelated | 120 Vcaps","description":"\u003ch2\u003eElemental Magnesium 200mg per Capsule | From Magnesium Bisglycinate (Chelated) and Magnesium Oxide | Health Canada Approved (NPN 80077844).\u003c\/h2\u003e\n\u003cp\u003eEach capsule contains Elemental Magnesium 200mg (from magnesium bisglycinate and magnesium oxide). Helps to maintain proper muscle function, including the heart muscle. Helps in the development and maintenance of bones and teeth. Helps to maintain the body's ability to metabolize nutrients. A factor in the maintenance of good health. Health Canada approved (NPN 80077844). Adults and adolescents (9 to 18 years of age): 1 capsule, 1 time per day. Vegan. Non-GMO. Made in Canada. 120 capsules (120 day supply at 1 capsule per day).\u003c\/p\u003e\n\u003ch3\u003eNPN Approved Uses\u003c\/h3\u003e\n\u003cp\u003e• Helps to maintain proper muscle function, including the heart muscle.\u003cbr\u003e• Helps in the development and maintenance of bones and teeth.\u003cbr\u003e• Helps to maintain the body's ability to metabolize nutrients.\u003cbr\u003e• A factor in the maintenance of good health.\u003c\/p\u003e\n\u003ch3\u003eKey Facts\u003c\/h3\u003e\n\u003cp\u003e• Elemental Magnesium 200mg per capsule (from magnesium bisglycinate and magnesium oxide)\u003cbr\u003e• Chelated form: magnesium bisglycinate (magnesium bound to two glycine molecules)\u003cbr\u003e• Once daily 1 capsule per day\u003cbr\u003e• Approved for adults and adolescents (9 to 18 years of age)\u003cbr\u003e• Health Canada approved (NPN 80077844)\u003cbr\u003e• Vegan hypromellose capsule\u003cbr\u003e• Non-GMO\u003cbr\u003e• 120 capsules (120 day supply 4 months at 1 capsule per day)\u003cbr\u003e• Made in Canada\u003cbr\u003e• Only 2 non-medicinal ingredients: Magnesium Stearate, Hypromellose\u003cbr\u003e• Also available in 300 capsules (300 day supply 10 months)\u003c\/p\u003e\n\u003ch3\u003eWhat This Product Does\u003c\/h3\u003e\n\u003cp\u003eThis formula helps to maintain proper muscle function, including the heart muscle. It helps in the development and maintenance of bones and teeth. It helps to maintain the body's ability to metabolize nutrients. It is a factor in the maintenance of good health. These are the Health Canada approved uses (NPN 80077844). This product is not intended to diagnose, treat, cure, or prevent any disease.\u003c\/p\u003e\n\u003ch3\u003eWhat Is Magnesium?\u003c\/h3\u003e\n\u003cp\u003eMagnesium is an essential mineral and the fourth most abundant mineral in the human body. Approximately 60% of the body's magnesium is stored in bone, 39% is found inside cells (primarily in muscle and soft tissue), and less than 1% is in the blood. Magnesium is a cofactor for over 300 enzymatic reactions in the body. It is required for all reactions involving ATP (adenosine triphosphate) the primary energy currency of cells. ATP must be bound to magnesium to be biologically active; the active form is Mg ATP. This means magnesium is involved in glycolysis, the citric acid cycle, oxidative phosphorylation, DNA synthesis, RNA synthesis, and protein synthesis.\u003c\/p\u003e\n\u003ch3\u003eWhat Does Chelated Mean?\u003c\/h3\u003e\n\u003cp\u003eChelation is the process of binding a mineral ion to an organic molecule to form a stable ring structure. The word chelate comes from the Greek word for claw (chele). In magnesium bisglycinate, one magnesium ion is bound to two glycine amino acid molecules. The chelate structure protects the magnesium ion from forming insoluble complexes in the digestive tract and allows it to be absorbed via amino acid transport pathways in the small intestine, rather than relying solely on passive diffusion.\u003c\/p\u003e\n\u003cp\u003eNon chelated magnesium salts that are not fully absorbed in the small intestine reach the large intestine, where they draw water into the intestinal lumen through osmosis. This osmotic effect causes loose stools or diarrhea the well known laxative effect of magnesium supplements. Chelated magnesium bisglycinate is absorbed more efficiently in the small intestine, reducing the amount that reaches the large intestine and therefore reducing the osmotic laxative effect. This makes bisglycinate significantly gentler on the digestive system than non-chelated magnesium forms.\u003c\/p\u003e\n\u003ch3\u003eUnderstanding the Magnesium Source in This Formula\u003c\/h3\u003e\n\u003cp\u003eThe medicinal ingredient in this formula is Elemental Magnesium 200mg, derived from a blend of magnesium bisglycinate and magnesium oxide. Magnesium bisglycinate is the primary, chelated form and provides the majority of the bioavailable magnesium. Magnesium oxide has a lower bioavailability than bisglycinate but a high elemental magnesium content per gram, making it useful as a secondary source to achieve the 200mg elemental magnesium target per capsule. The combination of bisglycinate (for bioavailability and digestive gentleness) and oxide (for elemental magnesium density) is a common approach in magnesium bisglycinate formulas.\u003c\/p\u003e\n\u003ch3\u003eThe Role of Glycine\u003c\/h3\u003e\n\u003cp\u003eGlycine is a non-essential amino acid — the smallest of the 20 amino acids. In magnesium bisglycinate, two glycine molecules are bound to each magnesium ion. When the chelate is absorbed, the glycine is released along with the magnesium. Glycine has its own roles in the body: it is a component of collagen (the most abundant protein in the body), a precursor to glutathione (the body's primary intracellular antioxidant), and an inhibitory neurotransmitter in the spinal cord and brainstem. At the dose in this formula, the glycine contribution is modest but present as a co-benefit of the chelated form.\u003c\/p\u003e\n\u003ch3\u003eMagnesium and Muscle Function\u003c\/h3\u003e\n\u003cp\u003eMagnesium is required for both muscle contraction and relaxation. Calcium triggers muscle contraction by binding to troponin and initiating the actin-myosin interaction. Magnesium is required for the SERCA pump (sarco\/endoplasmic reticulum Ca2+-ATPase), an ATP-dependent pump that moves calcium back into the sarcoplasmic reticulum after contraction, allowing the muscle to relax. Without adequate magnesium, this calcium recycling is impaired. This mechanism applies to all muscle types, including skeletal muscle and cardiac muscle (the heart). The NPN approved use specifically includes the heart muscle because the heart is a continuously working muscle that depends on this calcium-magnesium balance for every heartbeat.\u003c\/p\u003e\n\u003ch3\u003eMagnesium and Bone\u003c\/h3\u003e\n\u003cp\u003eApproximately 60% of the body's magnesium is stored in bone. Magnesium is a structural component of the hydroxyapatite crystal lattice that gives bone its hardness and rigidity. Magnesium is also required for the activation of Vitamin D: the enzyme that converts 25-hydroxyvitamin D (the storage form) to 1,25-dihydroxyvitamin D (the active form, calcitriol) requires magnesium as a cofactor. Active Vitamin D is required for calcium absorption from the intestine. Magnesium deficiency can therefore impair Vitamin D activation and indirectly affect calcium metabolism, bone mineralization, and tooth enamel formation.\u003c\/p\u003e\n\u003ch3\u003eMagnesium and Nutrient Metabolism\u003c\/h3\u003e\n\u003cp\u003eMagnesium is a cofactor for over 300 enzymatic reactions. Because ATP must be bound to magnesium to be biologically active (Mg-ATP), magnesium is required for every ATP-dependent reaction in the body. This includes glycolysis (the breakdown of glucose to pyruvate), the citric acid cycle (Krebs cycle), and oxidative phosphorylation (ATP production in the mitochondria). Magnesium is also required for DNA and RNA polymerase enzymes, making it essential for DNA replication and gene expression.\u003c\/p\u003e\n\u003ch3\u003e120 Vcaps vs. 300 Vcaps: Which Size Is Right?\u003c\/h3\u003e\n\u003cp\u003eThis product is available in two sizes under the same formula and NPN (80077844):\u003c\/p\u003e\n\u003cp\u003e• \u003cstrong\u003e120 capsules\u003c\/strong\u003e — 120 day supply (4 months) at 1 capsule per day. Ideal for those trying magnesium bisglycinate for the first time or who prefer a smaller initial commitment.\u003cbr\u003e• \u003cstrong\u003e300 capsules\u003c\/strong\u003e — 300 day supply (10 months) at 1 capsule per day. Better value per capsule for those who have confirmed this formula works for them and want a longer supply.\u003c\/p\u003e\n\u003cp\u003eBoth sizes contain the identical formula: Elemental Magnesium 200mg (from magnesium bisglycinate and magnesium oxide), with only 2 non-medicinal ingredients (Magnesium Stearate, Hypromellose).\u003c\/p\u003e\n\u003ch3\u003eUnderstanding the Dose and Supply\u003c\/h3\u003e\n\u003cp\u003eThe recommended dose is 1 capsule per day. At 120 capsules and 1 capsule per day, one bottle provides a 120 day supply (4 months). This formula is approved for adults and adolescents 9 to 18 years of age.\u003c\/p\u003e\n\u003ch3\u003eUnderstanding the Ingredient Content\u003c\/h3\u003e\n\u003cp\u003e\u003cstrong\u003eElemental Magnesium (from magnesium bisglycinate and magnesium oxide):\u003c\/strong\u003e 200mg per capsule\u003cbr\u003e\u003cstrong\u003eSuggested Use:\u003c\/strong\u003e Adults and adolescents (9 to 18 years of age): 1 capsule, 1 time per day.\u003cbr\u003e\u003cstrong\u003eCapsules per bottle:\u003c\/strong\u003e 120 (120 day supply — 4 months)\u003cbr\u003e\u003cstrong\u003eNon Medicinal Ingredients:\u003c\/strong\u003e Magnesium Stearate, Hypromellose\u003c\/p\u003e\n\u003ch3\u003eWho May Consider This Product\u003c\/h3\u003e\n\u003cp\u003e• Adults and adolescents (9 to 18 years of age) seeking a daily magnesium supplement\u003cbr\u003e• Those who want chelated magnesium bisglycinate for improved digestive tolerance compared to non-chelated forms\u003cbr\u003e• Those who want a once-daily formula with a 4-month supply per bottle\u003cbr\u003e• Those who want a clean formula with only 2 non-medicinal ingredients\u003cbr\u003e• Vegans (hypromellose capsule, no animal-derived ingredients)\u003cbr\u003e• Those trying magnesium bisglycinate for the first time (120 capsule size before committing to the 300 capsule size)\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eConsult a health care practitioner before use if:\u003c\/strong\u003e you are pregnant or breastfeeding; you have kidney disease or impaired kidney function; you are taking antibiotics (tetracyclines or fluoroquinolones), bisphosphonates, or diuretics.\u003c\/p\u003e\n\u003cp\u003eDo not exceed the recommended dose.\u003c\/p\u003e\n\u003ch3\u003eQuality and Purity\u003c\/h3\u003e\n\u003cp\u003e• Health Canada approved (NPN 80077844)\u003cbr\u003e• Elemental Magnesium 200mg per capsule (from magnesium bisglycinate and magnesium oxide)\u003cbr\u003e• Only 2 non-medicinal ingredients: Magnesium Stearate, Hypromellose\u003cbr\u003e• Vegan hypromellose capsule\u003cbr\u003e• Non-GMO\u003cbr\u003e• 120 capsules (120 day supply)\u003cbr\u003e• Made in Canada\u003c\/p\u003e\n\u003ch3\u003eStorage\u003c\/h3\u003e\n\u003cp\u003eStore in a cool, dry place away from direct sunlight and moisture. Keep bottle tightly sealed after each use.\u003c\/p\u003e\n\u003ch3\u003eSafety Information and Cautions\u003c\/h3\u003e\n\u003cp\u003eConsult a health care practitioner prior to use if you are pregnant or breastfeeding.\u003c\/p\u003e\n\u003cp\u003eConsult a health care practitioner prior to use if you have kidney disease or impaired kidney function. Magnesium is primarily excreted by the kidneys and can accumulate in individuals with reduced kidney function.\u003c\/p\u003e\n\u003cp\u003eConsult a health care practitioner prior to use if you are taking antibiotics (tetracyclines or fluoroquinolones), bisphosphonates (used for bone density), or diuretics, as magnesium can affect the absorption or activity of these medications.\u003c\/p\u003e\n\u003cp\u003eDo not exceed the recommended dose.\u003c\/p\u003e\n\u003cp\u003eThis product is not intended to diagnose, treat, cure, or prevent any disease.\u003c\/p\u003e\n\u003cp\u003eKeep out of reach of children.\u003c\/p\u003e\n\u003ch3\u003eAbout This Product\u003c\/h3\u003e\n\u003cp\u003e\u003cstrong\u003eWhat it is:\u003c\/strong\u003e Elemental Magnesium 200mg per capsule, from a blend of magnesium bisglycinate (chelated) and magnesium oxide. Only 2 non-medicinal ingredients. Vegan. 120 capsules (120 day supply — 4 months). Also available in 300 capsules (300 day supply 10 months).\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eWhat it does:\u003c\/strong\u003e Helps to maintain proper muscle function, including the heart muscle. Helps in the development and maintenance of bones and teeth. Helps to maintain the body's ability to metabolize nutrients. A factor in the maintenance of good health (NPN 80077844).\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eWhy bisglycinate:\u003c\/strong\u003e Chelated magnesium bisglycinate is absorbed via amino acid transport pathways in the small intestine, reducing the osmotic laxative effect common with non-chelated magnesium forms. The chelate structure (magnesium bound to two glycine molecules) protects the magnesium from forming insoluble complexes in the digestive tract.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eWhy bisglycinate + oxide:\u003c\/strong\u003e Magnesium bisglycinate provides bioavailability and digestive gentleness. Magnesium oxide provides high elemental magnesium density per gram. The blend achieves 200mg elemental magnesium per capsule.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eHow to take it:\u003c\/strong\u003e Adults and adolescents (9 to 18 years): 1 capsule per day. 120 capsules = 120 day supply (4 months).\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eWho it is for:\u003c\/strong\u003e Adults and adolescents (9 to 18 years). Vegan. Consult a health care practitioner before use if pregnant, breastfeeding, have kidney disease, or are taking tetracyclines, fluoroquinolones, bisphosphonates, or diuretics. Do not exceed the recommended dose.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eWhere it is made:\u003c\/strong\u003e Canada. Non-GMO. Health Canada approved (NPN 80077844).\u003c\/p\u003e","brand":"Nutridom","offers":[{"title":"Default Title","offer_id":44796380643491,"sku":"N145","price":31.5,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0623\/6589\/2771\/files\/Magnesium_Bisglycinate_200mg_Elemental_Chelated_120_Vcaps.jpg?v=1776110576","url":"https:\/\/nutridom.ca\/products\/magnesium-bisglycinate-200mg-elemental-chelated-120-vcaps","provider":"Nutridom","version":"1.0","type":"link"}