Magnesium L-Threonate | Brain Health and Cognitive Support | 120 Vegan Capsules

Each serving (3 capsules) delivers 2,085mg of magnesium L-threonate complex providing 150mg of elemental magnesium. Magnesium L-threonate is the only form of magnesium demonstrated to effectively cross the blood-brain barrier, supporting cognitive function, mental clarity, and brain health alongside the general magnesium benefits of muscle function and nervous system support.

Health Canada licensed NPN 80136177. Vegan. Non-GMO. Gluten free. Soy free. Made in Canada. 120 vegan capsules (40 servings).

Consult a healthcare practitioner before use if you are pregnant or breastfeeding, have kidney disease or impaired kidney function, or are taking medications. Do not exceed the recommended dose.

How This Product Is Made

Magnesium L-threonate is produced by chelating magnesium ions to threonic acid, a metabolite of vitamin C (L-ascorbic acid). The chelation creates a stable compound in which the magnesium is bound to the threonate molecule, allowing it to be transported across the blood-brain barrier via active transport mechanisms rather than relying on passive diffusion. This specific chelate was developed through research at MIT and is the form used in peer-reviewed studies on magnesium and cognitive function. The magnesium L-threonate complex is encapsulated in Canada in a GMP certified facility under Health Canada oversight using a hypromellose (vegetable) capsule shell. Gluten free. Soy free. Non-GMO.

What Is Magnesium L-Threonate?

Magnesium L-threonate is a chelated form of magnesium in which the mineral is bound to threonic acid, a vitamin C metabolite. Most forms of magnesium (oxide, citrate, bisglycinate) are absorbed in the gastrointestinal tract but have limited ability to cross the blood-brain barrier. Magnesium L-threonate was specifically developed to address this limitation. It is the only form of magnesium shown in research to significantly raise magnesium levels in the brain and cerebrospinal fluid, making it the preferred form for cognitive and brain health support.

Why Does the Brain Need Magnesium?

Magnesium is a critical cofactor in the brain. It regulates NMDA (N-methyl-D-aspartate) receptors, the primary receptors involved in synaptic plasticity, learning, and memory formation. Magnesium acts as a natural NMDA receptor blocker at rest, preventing excessive calcium influx and excitotoxicity. During learning, controlled NMDA receptor activation allows synaptic strengthening (long-term potentiation). Adequate brain magnesium levels are required for this process to function normally. Magnesium also supports the synthesis of ATP in neurons, the production of neurotransmitters, and the regulation of neuronal excitability.

Key Benefits

• Supports cognitive function and brain health Health Canada licensed claim under NPN 80136177
• Supports nervous system function Health Canada licensed claim under NPN 80136177
• Supports muscle function Health Canada licensed claim under NPN 80136177
• Supports relaxation and calmness Health Canada licensed claim under NPN 80136177
• 2,085mg magnesium L-threonate complex per serving 695mg per capsule | 150mg elemental magnesium per serving | 50mg per capsule
• Blood-brain barrier crossing form Only form of magnesium demonstrated to raise brain magnesium levels in research
• Source: magnesium chelated to threonic acid Threonic acid is a metabolite of vitamin C | Developed through MIT research
• Vegan capsule Hypromellose shell, no gelatin or animal derived ingredients
• Health Canada licensed NPN 80136177 | GMP certified | Made in Canada
• Non-GMO | Gluten free | Soy free
• 120 vegan capsules 40 servings at 3 capsules per day

How It Works

Blood-Brain Barrier Crossing

The blood-brain barrier is a selective membrane that restricts most substances from entering the brain. Magnesium L-threonate crosses this barrier via active transport mechanisms associated with the threonate molecule, allowing it to raise magnesium concentrations in the brain and cerebrospinal fluid. Other magnesium forms do not achieve this to the same degree.

NMDA Receptor Regulation and Synaptic Plasticity

Magnesium regulates NMDA receptors, which are central to synaptic plasticity, learning, and memory. At rest, magnesium blocks NMDA receptors, preventing excessive calcium influx. During learning, controlled NMDA activation allows synaptic strengthening (long-term potentiation). Adequate brain magnesium is required for this process. Low brain magnesium is associated with reduced synaptic density and impaired cognitive function.

Nervous System and Muscle Function

Magnesium regulates neurotransmitter release and neuronal excitability throughout the nervous system. It is required for the SERCA pump that moves calcium out of muscle cells after contraction, allowing muscles to relax. These mechanisms underlie the NPN licensed claims for nervous system function, muscle function, and relaxation.

Medicinal Ingredient (per serving, 3 capsules)

• Magnesium L-Threonate complex 2,085mg Providing elemental magnesium 150mg | Source: magnesium chelated to threonic acid (vitamin C metabolite) | Supports cognitive function, nervous system function, muscle function, and relaxation | NPN 80136177

Per capsule: Magnesium L-Threonate complex 695mg | Elemental magnesium 50mg.

Non-medicinal ingredients: Hypromellose (vegetable capsule shell). Vegan. Non-GMO. Gluten free. Soy free.

Quality and Trust

• NPN 80136177 Licensed by Health Canada as a Natural Health Product
• Made in Canada GMP certified facility under Health Canada oversight
• Source: magnesium L-threonate Magnesium chelated to threonic acid | Developed through MIT research | Blood-brain barrier crossing form
• Vegan capsule Hypromellose shell, no gelatin or animal derived ingredients
• Non-GMO | Gluten free | Soy free
• 120 vegan capsules 40 servings at 3 capsules per day

Who This Is For

Adults seeking brain-targeted magnesium support for cognitive function, mental clarity, and brain health, alongside the general magnesium benefits of nervous system function, muscle function, and relaxation. A good fit if you want the only form of magnesium demonstrated to raise brain magnesium levels, in a Health Canada licensed, vegan, Canadian-made formula with no unnecessary additives.

Consult a healthcare practitioner before use if you are pregnant or breastfeeding, have kidney disease or impaired kidney function, or are taking medications. Do not exceed the recommended dose.

How to Use

Adults: Take 3 capsules per day with food and a full glass of water, or as directed by a healthcare practitioner. At 3 capsules per day, 120 capsules provides 40 servings. Do not exceed the recommended dose.

Safety and Cautions

Consult a healthcare practitioner before use if you are pregnant or breastfeeding, have kidney disease or impaired kidney function (magnesium is excreted by the kidneys and can accumulate if kidney function is reduced), or are taking medications. Do not exceed the recommended dose. Store in a cool, dry place away from direct sunlight. Keep bottle tightly sealed. Keep out of reach of children.

NPN 80136177. This product is not intended to diagnose, treat, cure, or prevent any disease. All health claims are consistent with Health Canada's Natural Health Products Regulations.