Oral supplementation of specific collagen peptides has beneficial effects on human skin physiology: a double blind, placebo controlled study
Skin Pharmacology and Physiology, 2014
Each serving delivers 10g of hydrolyzed Type I marine collagen peptides sourced from wild-caught North Atlantic cod, haddock, and pollock skin. Enhanced with 100mg Vitamin C, 10mg Silicon, and 500mcg Biotin to support collagen synthesis, connective tissue integrity, and hair and nail health. Kosher certified.
Health Canada licensed NPN 80083214. Made in Canada. Wild-caught and sustainably sourced.
A hydrolyzed marine collagen peptide powder providing 10g of Type I collagen per serving, extracted from the skin of wild-caught North Atlantic cod, haddock, and pollock. Collagen is the most abundant structural protein in the human body, accounting for approximately 30% of total protein mass, and Type I is the predominant form in skin, bone, tendon, and connective tissue.
The collagen is enzymatically hydrolyzed to produce low molecular weight peptides of 2 to 5 kDa, a size range that allows efficient absorption across the intestinal epithelium and delivery to target tissues. The formula is enhanced with Vitamin C, Silicon, and Biotin to support endogenous collagen synthesis and connective tissue maintenance.
Licensed by Health Canada under NPN 80083214. Made in Canada. Kosher certified. Contains fish (cod, haddock, pollock). Not suitable for individuals with fish or seafood allergies.
Intact collagen protein has a molecular weight of approximately 300 kDa, too large for direct intestinal absorption. Enzymatic hydrolysis cleaves the collagen triple helix into smaller peptide chains of 2 to 5 kDa, a size range that allows absorption via intestinal peptide transporters and paracellular pathways. Human pharmacokinetic studies confirm that specific collagen dipeptides, particularly prolyl-hydroxyproline (Pro-Hyp) and hydroxyprolyl-glycine (Hyp-Gly), are detectable in blood within 60 minutes of oral ingestion and accumulate in skin tissue.
Marine collagen is predominantly Type I, the same collagen type that constitutes the majority of human skin, bone, and connective tissue. The smaller average peptide size of marine collagen compared to bovine collagen is associated with higher bioavailability. Cold-water North Atlantic species (cod, haddock, pollock) produce collagen with a well-characterized amino acid profile rich in glycine, proline, and hydroxyproline, the three amino acids that form the repeating Gly-X-Y tripeptide sequence of the collagen triple helix.
Marine collagen is composed of approximately 33% glycine, the smallest amino acid and the only one small enough to occupy the central position of the collagen triple helix. Proline and hydroxyproline together account for approximately 20 to 25% of the amino acid content and are essential for triple helix stability. Hydroxyproline is found almost exclusively in collagen and is used as a biomarker for collagen turnover in clinical research.
Vitamin C (ascorbic acid) is an obligate cofactor for prolyl-4-hydroxylase and lysyl hydroxylase, the enzymes that hydroxylate proline and lysine residues during collagen biosynthesis. Without adequate Vitamin C, these hydroxylation reactions cannot proceed, the collagen triple helix cannot form correctly, and newly synthesized collagen is unstable and rapidly degraded. Each serving provides 100mg of Vitamin C, supporting the enzymatic machinery required for endogenous collagen production.
Silicon is required for the activity of prolyl hydroxylase, the same enzyme that Vitamin C supports, and plays a role in the cross-linking of collagen and elastin fibers in the extracellular matrix. Silicon is concentrated in metabolically active connective tissue and bone, and dietary silicon intake is positively associated with bone mineral density and skin collagen content in epidemiological research. Each serving provides 10mg of Silicon.
Biotin (Vitamin B7) is required for the carboxylase enzymes involved in fatty acid synthesis and amino acid metabolism that support keratin production. Keratin is the structural protein of hair and nails, and biotin deficiency is associated with brittle nails and hair loss. Each serving provides 500mcg of Biotin, supporting the keratin infrastructure that complements collagen's structural role in hair follicles and nail beds.
Non-medicinal ingredients: Natural lemon flavour, citric acid, stevia leaf extract. No artificial colours, flavours, sweeteners, or preservatives.
Adults: Mix 1 scoop (10g) into 250ml of water, juice, or a beverage of your choice once daily. Stir or shake until fully dissolved.
Marine collagen peptides are heat stable and can be added to warm beverages. Consistent daily use over 8 to 12 weeks is recommended based on clinical trial protocols for collagen peptide supplementation. Ask a healthcare practitioner for use beyond the recommended duration.
Do not use if you have a fish or seafood allergy. Consult a healthcare practitioner before use if you are pregnant, breastfeeding, or taking prescription medications.
Store in a cool, dry place away from direct sunlight. Keep container tightly sealed. Do not refrigerate. Do not use if the seal is broken or missing. Keep out of reach of children.
NPN 80083214. This product is not intended to diagnose, treat, cure, or prevent any disease. All health claims are consistent with Health Canada's Natural Health Products Regulations.
Each serving delivers 10g of hydrolyzed Type I marine collagen peptides sourced from wild-caught North Atlantic cod, haddock, and pollock skin. Enhanced with 100mg Vitamin C, 10mg Silicon, and 500mcg Biotin to support collagen synthesis, connective tissue integrity, and hair and nail health. Kosher certified.
Health Canada licensed NPN 80083214. Made in Canada. Wild-caught and sustainably sourced.
A hydrolyzed marine collagen peptide powder providing 10g of Type I collagen per serving, extracted from the skin of wild-caught North Atlantic cod, haddock, and pollock. Collagen is the most abundant structural protein in the human body, accounting for approximately 30% of total protein mass, and Type I is the predominant form in skin, bone, tendon, and connective tissue.
The collagen is enzymatically hydrolyzed to produce low molecular weight peptides of 2 to 5 kDa, a size range that allows efficient absorption across the intestinal epithelium and delivery to target tissues. The formula is enhanced with Vitamin C, Silicon, and Biotin to support endogenous collagen synthesis and connective tissue maintenance.
Licensed by Health Canada under NPN 80083214. Made in Canada. Kosher certified. Contains fish (cod, haddock, pollock). Not suitable for individuals with fish or seafood allergies.
Intact collagen protein has a molecular weight of approximately 300 kDa, too large for direct intestinal absorption. Enzymatic hydrolysis cleaves the collagen triple helix into smaller peptide chains of 2 to 5 kDa, a size range that allows absorption via intestinal peptide transporters and paracellular pathways. Human pharmacokinetic studies confirm that specific collagen dipeptides, particularly prolyl-hydroxyproline (Pro-Hyp) and hydroxyprolyl-glycine (Hyp-Gly), are detectable in blood within 60 minutes of oral ingestion and accumulate in skin tissue.
Marine collagen is predominantly Type I, the same collagen type that constitutes the majority of human skin, bone, and connective tissue. The smaller average peptide size of marine collagen compared to bovine collagen is associated with higher bioavailability. Cold-water North Atlantic species (cod, haddock, pollock) produce collagen with a well-characterized amino acid profile rich in glycine, proline, and hydroxyproline, the three amino acids that form the repeating Gly-X-Y tripeptide sequence of the collagen triple helix.
Marine collagen is composed of approximately 33% glycine, the smallest amino acid and the only one small enough to occupy the central position of the collagen triple helix. Proline and hydroxyproline together account for approximately 20 to 25% of the amino acid content and are essential for triple helix stability. Hydroxyproline is found almost exclusively in collagen and is used as a biomarker for collagen turnover in clinical research.
Vitamin C (ascorbic acid) is an obligate cofactor for prolyl-4-hydroxylase and lysyl hydroxylase, the enzymes that hydroxylate proline and lysine residues during collagen biosynthesis. Without adequate Vitamin C, these hydroxylation reactions cannot proceed, the collagen triple helix cannot form correctly, and newly synthesized collagen is unstable and rapidly degraded. Each serving provides 100mg of Vitamin C, supporting the enzymatic machinery required for endogenous collagen production.
Silicon is required for the activity of prolyl hydroxylase, the same enzyme that Vitamin C supports, and plays a role in the cross-linking of collagen and elastin fibers in the extracellular matrix. Silicon is concentrated in metabolically active connective tissue and bone, and dietary silicon intake is positively associated with bone mineral density and skin collagen content in epidemiological research. Each serving provides 10mg of Silicon.
Biotin (Vitamin B7) is required for the carboxylase enzymes involved in fatty acid synthesis and amino acid metabolism that support keratin production. Keratin is the structural protein of hair and nails, and biotin deficiency is associated with brittle nails and hair loss. Each serving provides 500mcg of Biotin, supporting the keratin infrastructure that complements collagen's structural role in hair follicles and nail beds.
Non-medicinal ingredients: Natural lemon flavour, citric acid, stevia leaf extract. No artificial colours, flavours, sweeteners, or preservatives.
Adults: Mix 1 scoop (10g) into 250ml of water, juice, or a beverage of your choice once daily. Stir or shake until fully dissolved.
Marine collagen peptides are heat stable and can be added to warm beverages. Consistent daily use over 8 to 12 weeks is recommended based on clinical trial protocols for collagen peptide supplementation. Ask a healthcare practitioner for use beyond the recommended duration.
Do not use if you have a fish or seafood allergy. Consult a healthcare practitioner before use if you are pregnant, breastfeeding, or taking prescription medications.
Store in a cool, dry place away from direct sunlight. Keep container tightly sealed. Do not refrigerate. Do not use if the seal is broken or missing. Keep out of reach of children.
NPN 80083214. This product is not intended to diagnose, treat, cure, or prevent any disease. All health claims are consistent with Health Canada's Natural Health Products Regulations.
Serving Size: 1 Scoop (approx. 11g)
† Daily Value not established
Skin Pharmacology and Physiology, 2014
Archives of Dermatological Research, 2015
Nutrients, 2017
Research information is provided for educational purposes and does not replace the product's approved label information.