Nutridom D-Mannose with Canadian Cranberry 25x Extract (60 Veggie Capsules)

Medicinal Ingredients (per a capsule):
Cranberry 25x (Vaccinium macrocarpon)… 200mg (25:1 concentrated, equivalent to 5,000mg)
D-Mannose… 500mg

Non-Medicinal Ingredients:
Magnesium stearate, Hypromellose

Recommended Use:
(Traditionally) used in Herbal Medicine to help prevent (recurrent) urinary tract infections (UTIs).
(Used in Herbal Medicine to) help(s) prevent recurrent urinary tract infections (UTIs) in women.
Provides antioxidants for the maintenance of good health.

Recommended Dose:
Adults: 1 Capsule 2 times per day.

Duration of Use:
Use for a minimum of 4 weeks to see beneficial effects.

Cautions and Warnings:
Consult a health care practitioner prior to use if you are taking blood thinners, or if you have a history of kidney stones.
Consult a health care practitioner if symptoms persist or worsen.

Our D-Mannose with Cranberry 25X is a scientifically formulated blend aimed at promoting optimal urinary tract health and overall well-being. Enclosed in 60 easy-to-consume veggie capsules, this supplement has been granted the Natural Product Number (NPN) 80070066, certifying its safety, efficacy, and quality under Canada's rigorous health standards.

This supplement harnesses the power of two potent ingredients: D-Mannose and concentrated Cranberry extract (25:1 concentration, equivalent to 5,000mg). Together, they offer an effective, natural way to support urinary tract health.

D-Mannose, a type of sugar related to glucose, is beneficial for urinary tract health. This supplement contains 500mg of D-Mannose per capsule, providing a potent dose to help you maintain a healthy urinary tract.

The Cranberry extract is provided in a highly concentrated form, meaning you get the benefits of 5,000mg of cranberries in just 200mg of our extract. Cranberries have been traditionally used in herbal medicine to help prevent urinary tract infections, thanks to their ability to inhibit bacteria from adhering to the urinary tract walls.

Whether you are prone to recurring UTIs or simply looking to maintain a healthy urinary tract, our D-Mannose with Cranberry 25X supplement can provide the support you need. It is traditionally used in herbal medicine to help prevent urinary tract infections (UTIs), especially recurrent ones in women.

Moreover, the antioxidants in this supplement contribute to the maintenance of good health, further enhancing its benefits to your well-being.

The recommended dose for adults is 1 capsule 2 times per day.

Experience the difference that a scientifically formulated blend of D-Mannose and Cranberry 25X can make in promoting your urinary tract health and overall well-being. Try our D-Mannose with Cranberry 25X today.

What is a urinary tract infection (UTI)?
A UTI is an infection anywhere in the urinary tract including kidneys, ureters, bladder, prostate (in men), and urethra. E.coli is responsible for 80-90% of UTIs where the bacteria will enter the urethra and travel upwards to infect other areas of the urinary tract. The symptoms of UTI can include burning with urination (urethritis); pelvic pressure, blood in urine, and lower belly discomfort (cystitis); and back or side pain, fever, nausea, and vomiting (pyelonephritis). Unfortunately, it is common for UTIs to reoccur with up to 1/3rd of women experiencing recurrent infections after their first episode.

What are the effects of D-Mannose on UTI?
D-mannose is a monosaccharide naturally found in fruits, such as cranberries, oranges, and mangoes, and produced by our body. D-mannose, used as a dietary supplement, plays a critical role in reducing the risk for UTIs and preventing recurrent UTIs (rUTIs) because D-mannose can prevent bacteria from sticking to the walls of the urinary tract.
In a study involving 60 women who suffered from recurrent UTIs, it was demonstrated that D-mannose was more effective than antibiotic treatment for treating and preventing the recurrence of UTIs. The time to recurrence for the antibiotic treatment was an average of 52.7 days but the D-mannose treatment resulted in an average of 200 days without recurrent infections. Therefore, D-mannose appears to be a safe and promising alternative treatment for UTIs in adult women (1).

What are the effects of Cranberry on UTI?
Cranberries (Vaccinium macrocarpon) have been used in traditional medicine for the prevention and treatment of urinary tract infection (UTI) due to their distinctive source of flavonoids, particularly proanthocyanidins, anthocyanidins, and phenolic acids. Cranberry polyphenols function as anti-adhesive agents that prevent pathogens from sticking to the cells that line the urinary tract (2). Cranberry has also been shown to help alleviate the symptoms of UTIs by decreasing pain and inflammation.
A randomized, placebo-controlled study found that a cranberry supplement had the ability to prevent the adhesion of E.coli in the urinary tract greater than placebo for up to 24 hours (2).

What are the benefits of the D-Mannose with Cranberry 25X ?
• helps to treat acute urinary tract infections (UTIs)
• helps to prevent recurrent urinary tract infections (rUTIs)
• helps to reduce the symptoms of urinary tract infections (UTIs)
• provides antioxidants for the maintenance of good health

References
1. Porru, D., Parmigiani, A., Tinelli, C., Barletta, D., Choussos, D., Di Franco, C., Bobbi, V., Bassi, S., Miller, O., Gardella, B., Nappi, R. E., Spinillo, A., & Rovereto, B. (2014). Oral D-mannose in recurrent urinary tract infections in women: a pilot study. Journal of Clinical Urology, 7(3), 208–213.
2. Liu, H., Howell, A. B., Zhang, D. J., & Khoo, C. (2019). A randomized, double-blind, placebo-controlled pilot study to assess bacterial anti-adhesive activity in human urine following consumption of a cranberry supplement. Food & Function, 1(12), 7645–7652.