High Potency L-Arginine 1000mg

Nutridom L-Arginine delivers 1000mg of pharmaceutical-grade free-form L-arginine HCL per tablet. May support nitric oxide production, healthy circulation, exercise performance, and cardiovascular wellness. Each bottle contains 120 tablets (2-4 month supply).

Why Choose Nutridom L-Arginine

• 1000mg pharmaceutical grade L-arginine HCL per tablet
• Free-form for optimal absorption
• May support nitric oxide (NO) production
• May enhance blood flow and circulation
• 120 tablets (2-4 month supply)
• Made in Canada in GMP certified facility
• Third-party tested for purity and potency
• Vegan, non-GMO, gluten-free, soy-free

Clinically Studied Benefits

Research suggests L-arginine may support nitric oxide production, improve blood flow, and support cardiovascular health. Studies indicate it serves as a substrate for nitric oxide synthase enzymes. Widely used by athletes and individuals supporting vascular wellness.

Quality & Purity

Made in Canada • Pharmaceutical-grade L-arginine HCL • GMP certified facility • Third-party tested • Vegan tablets • Non-GMO • Gluten-free • No artificial additives

Suggested Use

Take 2-3 tablets (2000-3000mg) daily, 30-60 minutes before exercise for performance support, or divided throughout the day for circulation support. Consistent daily use for 2-4 weeks may show best results.

Who Uses L-Arginine

Athletes and fitness enthusiasts, individuals seeking circulation support, those focused on cardiovascular wellness, people supporting exercise performance, and anyone interested in nitric oxide optimization.

What is L-Arginine

L-arginine is a semi-essential amino acid, meaning the body can produce it but may require dietary supplementation during periods of growth, illness, or intense physical activity. It serves as a substrate for nitric oxide synthase (NOS) enzymes, which convert arginine to nitric oxide (NO), a signaling molecule for vascular health.

How L-Arginine Works

Research suggests L-arginine works by serving as substrate for nitric oxide synthase enzymes, which convert it to nitric oxide (NO). NO may help relax blood vessels, support blood flow and oxygen delivery, and support endothelial function.

Nitric Oxide Production

L-arginine is a precursor to nitric oxide. Research shows it provides substrate for endothelial nitric oxide synthase (eNOS), the enzyme responsible for NO production in blood vessels. A 2011 study in the American Journal of Physiology found that arginine supplementation increased NO bioavailability in healthy adults.

Cardiovascular & Circulation Support

Studies suggest L-arginine may support cardiovascular health. A 2016 meta-analysis in the Journal of Nutrition found that arginine supplementation was associated with improved endothelial function. Research indicates it may support arterial flexibility and vascular health.

Exercise Performance Support

Research on L-arginine for exercise performance shows varied results. A 2017 review in the Journal of the International Society of Sports Nutrition found that while arginine may improve blood flow, effects on exercise performance were inconsistent. Studies suggest L-citrulline may be more effective for performance due to better bioavailability.

Blood Flow During Exercise

Studies indicate L-arginine may enhance blood flow during exercise. Research suggests increased NO production may improve oxygen and nutrient delivery to working muscles. However, a 2012 study found that arginine's benefits may be limited by rapid metabolism in the liver and intestines.

Muscle Recovery Support

Research suggests L-arginine may support muscle recovery through improved blood flow and nutrient delivery. Studies indicate it may help with protein synthesis. However, evidence is mixed, with some studies showing benefits and others showing minimal effects.

Growth Hormone Support

Studies suggest L-arginine may influence growth hormone patterns. Research indicates high dose arginine (5-9 grams) may support growth hormone activity, particularly when taken before sleep or exercise. A 2008 study found arginine supplementation influenced growth hormone levels in resistance-trained men.

Vascular Health Support

Research suggests L-arginine may support vascular health in men. A 2019 review found that arginine supplementation (3-5 grams daily) may support vascular function. Studies indicate improved blood flow may support overall vascular health.

Immune Function

L-arginine plays a role in immune cell function. Research suggests it may support T-cell activity, wound healing, and immune response. Studies indicate arginine requirements may increase during illness, injury, or periods of immune challenge.

Wound Healing Support

Studies suggest L-arginine may support wound healing. Research indicates it's required for collagen synthesis, immune function, and tissue repair. A 2014 review found that arginine supplementation may support wound healing in surgical patients.

L-Arginine vs L-Citrulline

While both support NO production, research suggests L-citrulline may be more effective. A 2011 study in the British Journal of Nutrition found citrulline supplementation increased plasma arginine levels more than arginine itself. This is because arginine undergoes significant first pass metabolism, while citrulline bypasses it and converts to arginine in the kidneys.

ADMA Competition

Asymmetric dimethylarginine (ADMA) is an endogenous compound that competes with arginine for NOS enzymes. Research suggests ADMA levels may increase with age and cardiovascular risk factors. Arginine supplementation may help by providing additional substrate.

Bioavailability Considerations

Research indicates L-arginine has relatively limited oral bioavailability due to extensive first-pass metabolism in the liver and intestines. Studies show that a significant portion of oral arginine is metabolized before reaching systemic circulation. This is why L-citrulline is often preferred for NO support.

Research & Clinical Studies

L-arginine has been extensively studied for cardiovascular health, exercise performance, and vascular function. Clinical trials have explored doses ranging from 3-10 grams daily. Results vary, with some studies showing benefits and others showing minimal effects, likely due to bioavailability considerations.

Dosage & Timing

Clinically studied doses range from 3-10 grams daily. For cardiovascular support, 3-6 grams daily in divided doses. For exercise support, 3-6 grams 30-60 minutes pre-workout. For growth hormone support, 5-9 grams before sleep. Nutridom provides 1000mg per tablet (take 3-6 tablets for clinical doses).

Arginine + Citrulline Synergy

Research suggests combining L-arginine with L-citrulline may provide enhanced NO support. Citrulline bypasses first pass metabolism and provides sustained arginine elevation, while direct arginine provides immediate substrate. Studies indicate this combination may optimize NO production.

Complementary Nutrients

L-arginine works synergistically with L-citrulline (sustained arginine elevation), beetroot extract (additional NO support), pine bark extract (supports NO production), vitamin C (supports NO stability), and antioxidants (protect NO from oxidative stress).

Age Related NO Considerations

Research indicates nitric oxide production may decline with age due to reduced NOS enzyme activity, increased ADMA levels, and oxidative stress. Studies suggest arginine supplementation may help maintain NO levels in older adults, potentially supporting vascular health.

Important Considerations

Generally well tolerated at recommended doses. May cause digestive upset at very high doses (>10g). Avoid if you have active herpes simplex virus. Consult healthcare provider before use if taking blood pressure medications, have cardiovascular conditions, or take any medications. May interact with certain medications.

These statements have not been evaluated by Health Canada or the FDA. This product is not intended to diagnose, treat, cure, or prevent any disease.