Saw palmetto for benign prostatic hyperplasia: a Cochrane systematic review
Cochrane Database of Systematic Reviews, 2012
Eight ingredient prostate and urinary health formula for men Saw Palmetto (Serenoa repens) fruit 250 mg, Greater Nettle (Urtica dioica) herb top 50 mg, Lycopene 2 mg, Zinc (Zinc Oxide) 10 mg, Copper (Copper (II) Gluconate) 1 mg, Vitamin B6 (Pyridoxal 5-Phosphate) 1 mg, Selenium (Selenomethionine) 30 mcg, Vitamin D3 (Cholecalciferol) 5 mcg.
Saw Palmetto fruit extract inhibits 5-alpha-reductase the enzyme that converts testosterone to dihydrotestosterone (DHT), the primary androgen responsible for prostate tissue growth supporting normal prostate size and urinary flow. Greater Nettle herb top inhibits sex hormone-binding globulin (SHBG), modulates prostate cell growth factors, and supports a healthy inflammatory response in prostate tissue. The two are among the most clinically studied botanicals for prostate and urinary health and are frequently combined in research.
Lycopene is a carotenoid antioxidant selectively accumulated by the prostate gland. Zinc is present in higher concentrations in the prostate than in any other soft tissue, supporting prostate cell function and testosterone metabolism. Selenium (as selenomethionine, the most bioavailable organic form) is a cofactor for glutathione peroxidase the primary antioxidant enzyme in prostate tissue. Vitamin D3 acts through vitamin D receptors expressed in prostate tissue. Vitamin B6 is provided as pyridoxal 5-phosphate, the active coenzyme form requiring no hepatic conversion. Copper is included to maintain zinc to copper balance, as ongoing zinc supplementation competes with copper for intestinal absorption.
Eight ingredient prostate and urinary health formula for men Saw Palmetto (Serenoa repens) fruit 250 mg, Greater Nettle (Urtica dioica) herb top 50 mg, Lycopene 2 mg, Zinc (Zinc Oxide) 10 mg, Copper (Copper (II) Gluconate) 1 mg, Vitamin B6 (Pyridoxal 5-Phosphate) 1 mg, Selenium (Selenomethionine) 30 mcg, Vitamin D3 (Cholecalciferol) 5 mcg.
Saw Palmetto fruit extract inhibits 5-alpha-reductase the enzyme that converts testosterone to dihydrotestosterone (DHT), the primary androgen responsible for prostate tissue growth supporting normal prostate size and urinary flow. Greater Nettle herb top inhibits sex hormone-binding globulin (SHBG), modulates prostate cell growth factors, and supports a healthy inflammatory response in prostate tissue. The two are among the most clinically studied botanicals for prostate and urinary health and are frequently combined in research.
Lycopene is a carotenoid antioxidant selectively accumulated by the prostate gland. Zinc is present in higher concentrations in the prostate than in any other soft tissue, supporting prostate cell function and testosterone metabolism. Selenium (as selenomethionine, the most bioavailable organic form) is a cofactor for glutathione peroxidase the primary antioxidant enzyme in prostate tissue. Vitamin D3 acts through vitamin D receptors expressed in prostate tissue. Vitamin B6 is provided as pyridoxal 5-phosphate, the active coenzyme form requiring no hepatic conversion. Copper is included to maintain zinc to copper balance, as ongoing zinc supplementation competes with copper for intestinal absorption.
Serving Size: 2 Capsules
Servings Per Container: 30
† Daily Value not established.
Cochrane Database of Systematic Reviews, 2012
World Journal of Urology, 2005
Journal of the National Cancer Institute, 2002
Research information is provided for educational purposes and does not replace the product's approved label information.