{"product_id":"alpha-gpc-400mg-99-purity-choline-source-cognitive-function","title":"Alpha GPC 400mg | 99% Purity | Choline Source | Cognitive Function","description":"\u003ch2\u003eAlpha GPC 400mg | 99% Purity | L-alpha-Glycerophosphorylcholine | Source of Choline | Cognitive Function Support\u003c\/h2\u003e\n\n\u003cp\u003eEach capsule contains 400mg of Alpha GPC (L-alpha-Glycerophosphorylcholine, also known as choline alfoscerate) at 99% purity, delivering approximately 396mg of actual Alpha GPC per capsule. Alpha GPC is the most bioavailable form of choline available in supplement form, crossing the blood-brain barrier efficiently to support brain choline levels and acetylcholine synthesis. As a source of choline, Alpha GPC supports cognitive function, memory, and overall brain health. The 99% purity specification is a critical quality distinction that sets this formula apart from the majority of Alpha GPC supplements on the market. Health Canada approved (NPN 80125440). 100% vegan, non-GMO, gluten-free, and soy-free. Made in Canada in a quality-controlled facility. 90 vegan capsules.\u003c\/p\u003e\n\n\u003ch3\u003eKey Benefits\u003c\/h3\u003e\n\n\u003cp\u003e• Source of choline\u003cbr\u003e\n• Supports cognitive function\u003cbr\u003e\n• Supports memory\u003cbr\u003e\n• Most bioavailable form of choline supplement\u003cbr\u003e\n• Crosses the blood-brain barrier efficiently\u003cbr\u003e\n• Supports acetylcholine synthesis in the brain\u003cbr\u003e\n• 400mg Alpha GPC per capsule at 99% purity\u003cbr\u003e\n• Approximately 396mg actual Alpha GPC per capsule\u003cbr\u003e\n• L-alpha-Glycerophosphorylcholine (choline alfoscerate)\u003cbr\u003e\n• Health Canada approved (NPN 80125440)\u003cbr\u003e\n• 90 vegan capsules\u003cbr\u003e\n• Made in Canada in a quality-controlled facility\u003cbr\u003e\n• 100% vegan and non-GMO\u003cbr\u003e\n• Gluten-free, dairy-free, soy-free\u003c\/p\u003e\n\n\u003ch3\u003eWhy 99% Purity Matters: The Most Important Alpha GPC Specification\u003c\/h3\u003e\n\n\u003cp\u003ePurity is the single most important specification when evaluating Alpha GPC supplements, yet it is frequently overlooked or misunderstood by consumers. Understanding purity is essential for comparing Alpha GPC products accurately.\u003c\/p\u003e\n\n\u003cp\u003e\u003cstrong\u003eThe 50% vs. 99% Purity Difference:\u003c\/strong\u003e The majority of Alpha GPC supplements sold globally use 50% purity Alpha GPC. At 50% purity, a capsule labeled as containing 400mg of Alpha GPC actually contains only 200mg of actual L-alpha-Glycerophosphorylcholine, with the remaining 200mg being silica or other carrier material used to stabilize the hygroscopic compound. A 99% purity Alpha GPC capsule at 400mg contains approximately 396mg of actual L-alpha-Glycerophosphorylcholine, nearly double the actual active compound of a 50% purity product at the same labeled dose.\u003c\/p\u003e\n\n\u003cp\u003e\u003cstrong\u003eWhy 50% Purity Is the Industry Standard:\u003c\/strong\u003e Pure Alpha GPC is highly hygroscopic, meaning it readily absorbs moisture from the air and becomes sticky and difficult to handle in manufacturing. To make it easier to process and encapsulate, most manufacturers blend Alpha GPC with silica at a 1:1 ratio, producing a 50% purity powder that is stable and free-flowing. This is a manufacturing convenience, not a quality standard.\u003c\/p\u003e\n\n\u003cp\u003e\u003cstrong\u003eWhy 99% Purity Is Superior:\u003c\/strong\u003e At 99% purity, the Alpha GPC is processed to remove the carrier material, delivering nearly pure L-alpha-Glycerophosphorylcholine in each capsule. This requires more sophisticated manufacturing processes and higher quality raw material, but results in a significantly higher actual dose of Alpha GPC per capsule at the same labeled weight.\u003c\/p\u003e\n\n\u003cp\u003e\u003cstrong\u003ePractical Implication:\u003c\/strong\u003e A consumer taking one 400mg capsule of 99% purity Alpha GPC receives approximately 396mg of actual Alpha GPC. A consumer taking one 400mg capsule of 50% purity Alpha GPC receives only approximately 200mg of actual Alpha GPC. To match the actual Alpha GPC content of one 99% purity capsule, a consumer would need to take two 50% purity capsules.\u003c\/p\u003e\n\n\u003ch3\u003eWhat Is Alpha GPC?\u003c\/h3\u003e\n\n\u003cp\u003eAlpha GPC (L-alpha-Glycerophosphorylcholine, also known as choline alfoscerate) is a naturally occurring choline compound found in small amounts in the brain and in foods such as eggs, liver, and dairy products. It is a phospholipid precursor and the most bioavailable form of choline available in supplement form. Alpha GPC is distinct from other choline supplements such as choline bitartrate and CDP-choline (citicoline) in its ability to efficiently cross the blood-brain barrier and directly support brain choline levels.\u003c\/p\u003e\n\n\u003cp\u003e\u003cstrong\u003eCholine Alfoscerate:\u003c\/strong\u003e The pharmaceutical name for Alpha GPC is choline alfoscerate, the name used in Health Canada NPN labelling. Both names refer to the same compound: L-alpha-Glycerophosphorylcholine.\u003c\/p\u003e\n\n\u003cp\u003e\u003cstrong\u003eNatural Occurrence:\u003c\/strong\u003e Alpha GPC is found naturally in the brain as a breakdown product of phosphatidylcholine, a phospholipid that is a major structural component of cell membranes. It is also found in small amounts in foods including eggs, liver, wheat germ, and dairy products, though dietary amounts are far lower than supplemental doses.\u003c\/p\u003e\n\n\u003ch3\u003eCholine: An Essential Nutrient for Brain Health\u003c\/h3\u003e\n\n\u003cp\u003eCholine is an essential nutrient required for multiple critical functions in the body, with particular importance for brain health and nervous system function:\u003c\/p\u003e\n\n\u003cp\u003e\u003cstrong\u003eAcetylcholine Synthesis:\u003c\/strong\u003e Choline is the direct precursor to acetylcholine, one of the most important neurotransmitters in the brain and nervous system. Acetylcholine is involved in memory formation, learning, attention, and neuromuscular signaling. Alpha GPC supports brain choline levels, which in turn supports acetylcholine synthesis.\u003c\/p\u003e\n\n\u003cp\u003e\u003cstrong\u003ePhospholipid Synthesis:\u003c\/strong\u003e Choline is required for the synthesis of phosphatidylcholine, the primary phospholipid in cell membranes. Phosphatidylcholine is essential for the structural integrity and fluidity of cell membranes throughout the body, with particular importance in the brain where phospholipids are a major component of neuronal membranes.\u003c\/p\u003e\n\n\u003cp\u003e\u003cstrong\u003eMethyl Group Donor:\u003c\/strong\u003e Choline is a methyl group donor involved in methylation reactions throughout the body, including the methylation of homocysteine to methionine, contributing to normal homocysteine metabolism.\u003c\/p\u003e\n\n\u003cp\u003e\u003cstrong\u003eEssential Nutrient Status:\u003c\/strong\u003e Choline was recognized as an essential nutrient by the Institute of Medicine in 1998. The body can synthesize some choline endogenously, but not in sufficient amounts to meet daily requirements, making dietary and supplemental choline important for maintaining adequate choline status.\u003c\/p\u003e\n\n\u003ch3\u003eAlpha GPC vs. Other Choline Forms\u003c\/h3\u003e\n\n\u003cp\u003e\u003cstrong\u003eAlpha GPC vs. Choline Bitartrate:\u003c\/strong\u003e Choline bitartrate is the most common and least expensive form of choline supplement. It has lower bioavailability for brain choline support compared to Alpha GPC because it does not cross the blood-brain barrier as efficiently. Choline bitartrate is primarily used as a general choline source rather than a targeted brain choline supplement.\u003c\/p\u003e\n\n\u003cp\u003e\u003cstrong\u003eAlpha GPC vs. CDP-Choline (Citicoline):\u003c\/strong\u003e CDP-choline (citicoline) is another highly bioavailable choline form that crosses the blood-brain barrier. CDP-choline is converted to both choline and cytidine in the body, with cytidine further converted to uridine, a nucleotide with its own neurological effects. Alpha GPC delivers choline more directly and at a higher choline content per gram than CDP-choline. Alpha GPC contains approximately 40% choline by weight, while CDP-choline contains approximately 18% choline by weight.\u003c\/p\u003e\n\n\u003cp\u003e\u003cstrong\u003eAlpha GPC vs. Phosphatidylcholine:\u003c\/strong\u003e Phosphatidylcholine is a phospholipid found in lecithin supplements. While it is a natural choline source, it has lower bioavailability for brain choline support compared to Alpha GPC and contains a lower percentage of choline by weight.\u003c\/p\u003e\n\n\u003cp\u003e\u003cstrong\u003eWhy Alpha GPC Is the Premium Choline Form:\u003c\/strong\u003e Alpha GPC is the most bioavailable form of choline for brain support, crosses the blood-brain barrier efficiently, and delivers the highest choline content per gram among commonly available choline supplements. The 99% purity specification in this formula ensures that the full 400mg capsule weight is delivering actual Alpha GPC rather than carrier material.\u003c\/p\u003e\n\n\u003ch3\u003eCognitive Function and Memory Support\u003c\/h3\u003e\n\n\u003cp\u003eAlpha GPC supports cognitive function and memory through its role as a source of choline for acetylcholine synthesis in the brain. Acetylcholine is the primary neurotransmitter of the cholinergic system, which is involved in attention, learning, memory formation, and memory retrieval. By supporting brain choline levels, Alpha GPC supports the cholinergic system's ability to synthesize acetylcholine as needed for cognitive processes. Alpha GPC is one of the most studied choline supplements for cognitive function support and is used in clinical settings in Europe as a pharmaceutical-grade choline supplement.\u003c\/p\u003e\n\n\u003ch3\u003eUnderstanding the Dosage\u003c\/h3\u003e\n\n\u003cp\u003e\u003cstrong\u003eAlpha GPC (L-alpha-Glycerophosphorylcholine):\u003c\/strong\u003e 400mg per capsule\u003cbr\u003e\n\u003cstrong\u003ePurity:\u003c\/strong\u003e 99%\u003cbr\u003e\n\u003cstrong\u003eActual Alpha GPC per Capsule:\u003c\/strong\u003e approximately 396mg\u003cbr\u003e\n\u003cstrong\u003eSuggested Use:\u003c\/strong\u003e As directed by a healthcare practitioner\u003cbr\u003e\n\u003cstrong\u003eTotal Capsules:\u003c\/strong\u003e 90\u003cbr\u003e\n\u003cstrong\u003eNon-Medicinal Ingredients:\u003c\/strong\u003e Hypromellose (vegetable capsule shell), magnesium stearate, silica, cellulose\u003c\/p\u003e\n\n\u003cp\u003eConsult your healthcare provider to determine the appropriate dosage and timing for your individual needs.\u003c\/p\u003e\n\n\u003ch3\u003eWho May Consider This Product\u003c\/h3\u003e\n\n\u003cp\u003e• Individuals seeking a source of choline for brain health support\u003cbr\u003e\n• Those wanting cognitive function and memory support\u003cbr\u003e\n• People wanting the most bioavailable form of choline supplement\u003cbr\u003e\n• Those wanting 99% purity Alpha GPC for maximum actual Alpha GPC per capsule\u003cbr\u003e\n• Individuals interested in acetylcholine precursor supplementation\u003cbr\u003e\n• Those wanting a Health Canada approved choline supplement\u003cbr\u003e\n• Vegans and vegetarians seeking a plant-based choline source\u003cbr\u003e\n• Those seeking Canadian-made cognitive support supplements\u003c\/p\u003e\n\n\u003ch3\u003eQuality and Purity\u003c\/h3\u003e\n\n\u003cp\u003e• Health Canada approved (NPN 80125440)\u003cbr\u003e\n• 400mg Alpha GPC per capsule (L-alpha-Glycerophosphorylcholine)\u003cbr\u003e\n• 99% purity (approximately 396mg actual Alpha GPC per capsule)\u003cbr\u003e\n• Vegan capsules (hypromellose)\u003cbr\u003e\n• 90 capsules\u003cbr\u003e\n• Made in Canada in a quality-controlled facility\u003cbr\u003e\n• 100% vegan and non-GMO\u003cbr\u003e\n• Gluten-free, dairy-free, soy-free\u003c\/p\u003e\n\n\u003ch3\u003eStorage\u003c\/h3\u003e\n\n\u003cp\u003eStore in a cool, dry place away from direct sunlight. Keep bottle tightly sealed. Alpha GPC is hygroscopic and sensitive to moisture. Proper storage with the bottle tightly sealed preserves product quality and prevents moisture absorption.\u003c\/p\u003e\n\n\u003ch3\u003eSafety Information\u003c\/h3\u003e\n\n\u003cp\u003eConsult a healthcare professional before use if you are pregnant or breastfeeding, taking medications (particularly anticholinergic medications or scopolamine), or have a medical condition. Alpha GPC may interact with scopolamine and other anticholinergic drugs by opposing their effects. Do not exceed the recommended dose. This product is not intended to diagnose, treat, cure, or prevent any disease.\u003c\/p\u003e\n\n\u003cp\u003eKeep out of reach of children.\u003c\/p\u003e\n\n\u003cp\u003e\u003cem\u003eThis product is approved by Health Canada (NPN 80125440).\u003c\/em\u003e\u003c\/p\u003e\n\n\u003ch3\u003eAbout Alpha GPC 400mg | 99% Purity | Source of Choline for Cognitive Function Support\u003c\/h3\u003e\n\n\u003cp\u003eAlpha GPC (L-alpha-Glycerophosphorylcholine) is the most bioavailable form of choline supplement, crossing the blood-brain barrier efficiently to support brain choline levels and acetylcholine synthesis. At 400mg per capsule with 99% purity, this formula delivers approximately 396mg of actual Alpha GPC per capsule, nearly double the actual Alpha GPC content of a 50% purity product at the same labeled dose. As a source of choline, Alpha GPC supports cognitive function and memory. Health Canada approved (NPN 80125440), 100% vegan, and made in Canada in a quality-controlled facility.\u003c\/p\u003e","brand":"Nutridom","offers":[{"title":"Default Title","offer_id":45773772718243,"sku":"N284","price":44.99,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0623\/6589\/2771\/files\/Alpha_GPC_400_mg_99_percent_purity_choline_supplement_capsules.jpg?v=1774381493","url":"https:\/\/nutridom.ca\/zh\/products\/alpha-gpc-400mg-99-purity-choline-source-cognitive-function","provider":"Nutridom","version":"1.0","type":"link"}