{"product_id":"melatonin-10mg-fast-acting-sublingual-mint-tablet-sleep-and-circadian-support-300-tablets","title":"Melatonin 10mg | Fast Acting Sublingual Mint Tablet | Sleep and Circadian Support | 300 Tablets","description":"\u003ch2\u003eMelatonin 10mg | Fast-Acting Sublingual Mint Tablet | Sleep and Circadian Support | 300 Tablets\u003c\/h2\u003e\n\u003cp\u003eEach tablet delivers 10mg of Melatonin (N-acetyl-5-methoxytryptamine) in a sublingual mint format that dissolves under the tongue for direct absorption into the bloodstream, bypassing digestion and first-pass liver metabolism. Place under the tongue 10 to 30 minutes before bedtime.\u003c\/p\u003e\n\u003cp\u003eHelps reset the body's sleep-wake cycle. Supports sleep onset. Jet lag and shift work support. Health Canada licensed NPN 80135538. Vegan. Non-GMO. Gluten free. Dairy free. Soy free. No artificial colours or preservatives. Made in Canada. 300 tablets.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eDo not use if you are pregnant or breastfeeding. For adults 18 years and older only.\u003c\/strong\u003e\u003c\/p\u003e\n\u003ch2\u003eSource\u003c\/h2\u003e\n\u003cp\u003e\u003cstrong\u003eMelatonin source:\u003c\/strong\u003e Synthetically produced N-acetyl-5-methoxytryptamine. Melatonin is identical in structure to the hormone produced endogenously by the pineal gland from serotonin via N-acetyltransferase and hydroxyindole-O-methyltransferase. Synthetic production ensures pharmaceutical-grade purity and consistent potency. Not derived from animal pineal glands.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eFlavour:\u003c\/strong\u003e Peppermint flavour. Mannitol provides mild sweetness without significantly raising blood sugar.\u003c\/p\u003e\n\u003ch2\u003eWhat Is Melatonin and How Does It Support Sleep?\u003c\/h2\u003e\n\u003cp\u003eMelatonin (N-acetyl-5-methoxytryptamine) is a hormone produced by the pineal gland in response to darkness. As light levels fall in the evening, the suprachiasmatic nucleus (the brain's circadian clock) signals the pineal gland to begin melatonin secretion. Melatonin does not cause sleep directly the way a sedative does. It signals the timing of sleep by communicating to the circadian clock that it is nighttime, shifting the body toward sleep-readiness. Melatonin levels peak in the middle of the night and decline toward morning as light exposure increases.\u003c\/p\u003e\n\u003ch2\u003eWhat Is Sublingual Delivery and Why Is It Faster?\u003c\/h2\u003e\n\u003cp\u003eSublingual means under the tongue. The sublingual mucosa is highly vascularized, containing a dense network of capillaries. When a tablet dissolves under the tongue, the active ingredient is absorbed directly through this tissue into the bloodstream, bypassing digestion in the stomach and intestine and first pass metabolism in the liver. This results in faster onset compared to swallowing a tablet. For melatonin, faster onset allows more precise timing of the melatonin signal relative to the desired bedtime.\u003c\/p\u003e\n\u003ch2\u003eKey Benefits\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eHelps reset the body's sleep-wake cycle\u003c\/strong\u003e Health Canada licensed claim under NPN 80135538\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eSupports sleep onset\u003c\/strong\u003e Health Canada licensed claim under NPN 80135538\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eJet lag and shift work support\u003c\/strong\u003e Health Canada licensed claim under NPN 80135538\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003e10mg melatonin per tablet\u003c\/strong\u003e N-acetyl-5-methoxytryptamine | Synthetically produced, not from animal pineal glands\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eSublingual delivery\u003c\/strong\u003e Dissolves under the tongue for direct bloodstream absorption, bypassing digestion and first-pass liver metabolism\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eFast onset\u003c\/strong\u003e Take 10 to 30 minutes before bedtime | Croscarmellose sodium disintegrant ensures rapid dissolution\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eMint flavour\u003c\/strong\u003e Peppermint flavour with mannitol for a pleasant sublingual experience\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eVegan\u003c\/strong\u003e No gelatin | All excipients plant-derived or synthetic\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eHealth Canada licensed\u003c\/strong\u003e NPN 80135538 | Made in Canada\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003e300 tablets\u003c\/strong\u003e 300 day supply at 1 tablet per day\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2\u003eHow It Works\u003c\/h2\u003e\n\u003ch3\u003eMelatonin and the Circadian Clock\u003c\/h3\u003e\n\u003cp\u003eThe suprachiasmatic nucleus (SCN) in the hypothalamus is the brain's master circadian clock, governing the 24-hour sleep-wake cycle. The SCN receives light input from the retina via the retinohypothalamic tract and uses this information to time melatonin secretion from the pineal gland. Darkness triggers melatonin release; light suppresses it, particularly blue light (short-wavelength light from screens, LED lighting, and sunlight). Supplemental melatonin mimics this endogenous signal, helping to shift or reinforce the circadian timing of sleep onset.\u003c\/p\u003e\n\u003ch3\u003eWhy Sublingual Absorption Is Faster Than Swallowing\u003c\/h3\u003e\n\u003cp\u003eOral tablets must dissolve in the stomach, be absorbed through the intestinal wall, and pass through the liver (first-pass metabolism) before reaching systemic circulation. Each step adds time and reduces the amount of active ingredient that reaches the bloodstream. Sublingual absorption bypasses all three steps: the tablet dissolves under the tongue, and melatonin is absorbed directly through the sublingual mucosa into the capillary network, reaching systemic circulation rapidly. The croscarmellose sodium in this tablet is a disintegrant that causes rapid tablet breakdown on contact with moisture, accelerating dissolution.\u003c\/p\u003e\n\u003ch3\u003eJet Lag and Shift Work: Circadian Disruption\u003c\/h3\u003e\n\u003cp\u003eJet lag occurs when the body's circadian clock is misaligned with the local day-night cycle after rapid travel across time zones. Shift work disrupts the circadian clock by requiring wakefulness during the biological night. In both cases, endogenous melatonin secretion is timed to the old schedule, making it difficult to fall asleep at the new desired time. Supplemental melatonin taken at the target bedtime in the new time zone or schedule helps shift the circadian clock toward the desired timing.\u003c\/p\u003e\n\u003ch3\u003eMelatonin as a Timing Signal, Not a Sedative\u003c\/h3\u003e\n\u003cp\u003eMelatonin is not a sedative. It does not directly induce sleep the way benzodiazepines or antihistamines do. It acts as a chronobiotic, a compound that shifts the timing of the circadian clock. This distinction is important: melatonin is most effective when taken at the right time relative to the desired sleep onset, not simply as a sleep-inducing agent taken at any time.\u003c\/p\u003e\n\u003ch2\u003eMedicinal Ingredient (per tablet)\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eMelatonin (N-acetyl-5-methoxytryptamine) 10mg\u003c\/strong\u003e Source: synthetically produced | Not from animal pineal glands | NPN 80135538\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eNon-medicinal ingredients: Microcrystalline cellulose, magnesium stearate, croscarmellose sodium (disintegrant for rapid dissolution), mannitol (mild sweetness), peppermint flavour. No artificial colours or preservatives. Vegan. Gluten free. Dairy free. Soy free. Non-GMO.\u003c\/p\u003e\n\u003ch2\u003eQuality and Trust\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eNPN 80135538\u003c\/strong\u003e Licensed by Health Canada as a Natural Health Product\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eMade in Canada\u003c\/strong\u003e Quality-controlled facility\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eSynthetically produced melatonin\u003c\/strong\u003e Pharmaceutical-grade purity | Not from animal pineal glands\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eSublingual mint tablet\u003c\/strong\u003e Croscarmellose sodium for rapid dissolution | Peppermint flavour and mannitol for pleasant experience\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eVegan\u003c\/strong\u003e No gelatin, no animal derived ingredients\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eNon-GMO, gluten free, dairy free, soy free\u003c\/strong\u003e No artificial colours or preservatives\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003e300 tablets\u003c\/strong\u003e 300 day supply at 1 tablet per day\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2\u003eWho This Is For\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cstrong\u003eDo not use if you are pregnant or breastfeeding\u003c\/strong\u003e\u003c\/li\u003e\n\u003cli\u003eNot for use by individuals under 18 years of age\u003c\/li\u003e\n\u003cli\u003eAsk a healthcare practitioner before use if you are taking medications for seizure, blood pressure, immune suppression, mental state or sedation, steroids, or blood thinners, or if you have cardiovascular, immune, liver, or kidney disease, seizure disorder, asthma, or diabetes\u003c\/li\u003e\n\u003cli\u003eAsk a healthcare practitioner if sleeplessness persists for more than 4 weeks (chronic insomnia)\u003c\/li\u003e\n\u003cli\u003eStop use if allergy occurs or if you experience headache, confusion, or nausea\u003c\/li\u003e\n\u003cli\u003eAdults 18 and over seeking sleep onset support, circadian reset, or jet lag and shift work relief from a fast-acting sublingual melatonin tablet\u003c\/li\u003e\n\u003cli\u003eThose who want sublingual delivery for faster onset versus a swallowed tablet\u003c\/li\u003e\n\u003cli\u003eVegans and vegetarians seeking a gelatin free melatonin formula\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2\u003eHow to Use\u003c\/h2\u003e\n\u003cp\u003eAdults 18 years and older: Take 1 tablet, 1 time per day. Place under the tongue and allow to dissolve completely. Do not swallow whole. Take 10 to 30 minutes before bedtime.\u003c\/p\u003e\n\u003cp\u003eFor jet lag: take at the target bedtime in the new time zone. For shift work: take at the desired sleep time on the new schedule. Store in a cool, dry place away from direct sunlight. Keep bottle tightly sealed melatonin is sensitive to light.\u003c\/p\u003e\n\u003ch2\u003eSafety and Cautions\u003c\/h2\u003e\n\u003cp\u003e\u003cstrong\u003eDo not use if you are pregnant or breastfeeding.\u003c\/strong\u003e Not for use by individuals under 18 years of age.\u003c\/p\u003e\n\u003cp\u003eAsk a healthcare practitioner before use if you are taking medications for seizure, blood pressure, immune suppression, mental state or increased sedation, steroids, or blood thinners, or if you have cardiovascular, immune, liver, or kidney disease, seizure disorder, asthma, or diabetes. Ask a healthcare practitioner if sleeplessness persists for more than 4 weeks. Stop use if allergy occurs or if you experience headache, confusion, or nausea. Store in a cool, dry place away from direct sunlight. Keep out of reach of children.\u003c\/p\u003e\n\u003cp\u003eNPN 80135538. This product is not intended to diagnose, treat, cure, or prevent any disease. All health claims are consistent with Health Canada's Natural Health Products Regulations.\u003c\/p\u003e","brand":"Nutridom","offers":[{"title":"Default Title","offer_id":46101460287651,"sku":"N313","price":27.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0623\/6589\/2771\/files\/Melatonin_10_mg_fast_acting_mint_sublingual_tablets_300_count.jpg?v=1773173014","url":"https:\/\/nutridom.ca\/zh\/products\/melatonin-10mg-fast-acting-sublingual-mint-tablet-sleep-and-circadian-support-300-tablets","provider":"Nutridom","version":"1.0","type":"link"}