TUDCA 250mg with Choline | Tauroursodeoxycholic Acid | Purified Conjugated Bile Salt | 60 Vegan Capsules
Each capsule contains 250mg of TUDCA (Tauroursodeoxycholic Acid), a purified taurine-conjugated bile salt that occurs naturally in human bile, and 27.5mg of choline, an essential nutrient involved in liver lipid metabolism and phospholipid synthesis. TUDCA is the taurine conjugate of UDCA (ursodeoxycholic acid), a secondary bile acid naturally present in the human bile acid pool. Helps to maintain liver function. Source of choline. Health Canada approved (NPN 80133303). 100% vegan, non-GMO, gluten-free, and soy-free. Made in Canada in a quality-controlled facility. 60 vegan capsules.
Key Benefits
• Helps to maintain liver function
• Source of choline
• 250mg TUDCA (Tauroursodeoxycholic Acid) per capsule
• Purified taurine-conjugated bile salt naturally occurring in human bile
• 27.5mg choline per capsule
• Choline: essential nutrient for liver lipid metabolism and phospholipid synthesis
• TUDCA + choline for complementary liver nutritional support
• Health Canada approved (NPN 80133303)
• 60 vegan capsules
• Made in Canada in a quality-controlled facility
• 100% vegan and non-GMO
• Gluten-free, dairy-free, soy-free
What Is TUDCA?
TUDCA (Tauroursodeoxycholic Acid) is a bile salt that occurs naturally in the human body as a minor component of the bile acid pool. To understand TUDCA, it helps to understand the bile acid system it belongs to.
Bile Acids and Bile Salts: Bile acids are steroid-derived acids synthesized in the liver from cholesterol. They are the primary organic solutes in bile and are essential for the emulsification and absorption of dietary fats and fat-soluble vitamins in the small intestine. In the liver, bile acids are conjugated with either glycine or taurine to form bile salts, which are more water-soluble and more effective as emulsifying agents than unconjugated bile acids. The human bile acid pool consists of primary bile acids synthesized directly in the liver (cholic acid and chenodeoxycholic acid) and secondary bile acids produced by intestinal bacteria (deoxycholic acid and lithocholic acid), along with their glycine and taurine conjugates.
UDCA (Ursodeoxycholic Acid): UDCA is a secondary bile acid that constitutes a small fraction of the normal human bile acid pool (approximately 1 to 3%). It is also found in significant amounts in bear bile, from which it was first isolated (ursus is Latin for bear). UDCA is a hydrophilic bile acid, in contrast to the more hydrophobic bile acids such as deoxycholic acid and lithocholic acid. This hydrophilic character is significant because hydrophobic bile acids at high concentrations can be damaging to cell membranes, while hydrophilic bile acids are generally better tolerated by cells.
TUDCA (Tauroursodeoxycholic Acid): TUDCA is the taurine conjugate of UDCA — UDCA with a taurine molecule attached at its carboxyl group. Taurine conjugation increases the water solubility of UDCA further, improves its stability in the acidic environment of the stomach, and makes it more resistant to precipitation in bile. TUDCA is the form of UDCA found naturally in human bile and is the predominant form of UDCA in bear bile. As a taurine conjugate, TUDCA is one of the most water-soluble bile salts in the human bile acid pool.
TUDCA vs. UDCA: Why the Taurine Conjugation Matters
Water Solubility: TUDCA is significantly more water-soluble than UDCA due to the taurine conjugation. Greater water solubility means TUDCA remains in solution across a wider range of pH conditions and is less likely to precipitate in bile or the digestive tract.
Gastric Stability: Taurine conjugates are more stable in the acidic environment of the stomach than unconjugated bile acids. UDCA can be partially protonated and precipitate at low pH, while TUDCA's taurine conjugation provides greater stability across the pH range of the digestive tract.
Enterohepatic Circulation: Both TUDCA and UDCA are absorbed from the small intestine and enter the enterohepatic circulation — the recycling pathway by which bile salts are reabsorbed from the terminal ileum, transported back to the liver via the portal vein, and re-secreted into bile. TUDCA's greater water solubility and gastric stability support its absorption and participation in this cycle.
Natural Form: TUDCA is the form of UDCA that occurs naturally in human bile, making it the physiologically native form of this bile acid in the human body.
Bile Acids and the Enterohepatic Circulation
• The liver synthesizes bile acids from cholesterol and conjugates them with glycine or taurine to form bile salts
• Bile salts are secreted into bile and stored in the gallbladder between meals
• After a meal, the gallbladder contracts and releases bile into the duodenum for fat emulsification
• Bile salts emulsify dietary fats, breaking large fat droplets into smaller ones for digestion by pancreatic lipase
• Approximately 95% of bile salts are reabsorbed from the terminal ileum and transported back to the liver via the portal vein
• The liver extracts bile salts from portal blood and re-secretes them into bile, completing the enterohepatic cycle
• The average bile salt molecule undergoes this cycle approximately 4 to 12 times per day
• The approximately 5% of bile salts lost in stool is replaced by new synthesis from cholesterol in the liver
Liver Function Support
The liver is the central organ of bile acid metabolism. It synthesizes primary bile acids from cholesterol, conjugates them with glycine or taurine, secretes them into bile, and extracts them from portal blood during the enterohepatic cycle. TUDCA, as a naturally occurring hydrophilic bile salt, participates in the normal bile acid pool and supports the liver's bile acid handling and secretory function. Health Canada has approved this product (NPN 80133303) for helping to maintain liver function, reflecting the established role of TUDCA in hepatic bile acid physiology.
Choline: Essential Nutrient for Liver Lipid Metabolism
Choline is an essential nutrient recognized by the Institute of Medicine in 1998, required for multiple critical functions with particular importance for liver function and lipid metabolism:
Phosphatidylcholine Synthesis: Choline is the primary building block of phosphatidylcholine, the most abundant phospholipid in cell membranes and a major component of bile. Phosphatidylcholine in bile is essential for the formation of mixed micelles — the structures that solubilize cholesterol and bile salts in bile, preventing their precipitation and crystallization. Adequate choline is therefore important for normal bile composition and the liver's ability to maintain bile fluidity.
VLDL Export from the Liver: Phosphatidylcholine is a required structural component of VLDL (very low-density lipoprotein) particles, the lipoproteins that the liver uses to export triglycerides into the bloodstream. Without adequate choline for phosphatidylcholine synthesis, the liver's ability to export triglycerides as VLDL is impaired, which can lead to triglyceride accumulation in liver cells. Choline is therefore essential for normal hepatic lipid export and liver function.
Methyl Group Donation: Choline is a methyl group donor involved in methylation reactions throughout the body, including the methylation of homocysteine to methionine via betaine (a choline metabolite), connecting choline to the broader one-carbon metabolism network alongside folate and vitamin B12.
TUDCA and Choline Synergy: TUDCA and choline address complementary aspects of liver function. TUDCA contributes to the bile salt component of bile and supports bile flow and fat emulsification. Choline contributes to the phosphatidylcholine component of bile and supports hepatic lipid export via VLDL. Together they provide nutritional support for two distinct but interrelated aspects of liver and biliary function. Health Canada has approved this product (NPN 80133303) as a source of choline.
Understanding the Dosage
TUDCA (Tauroursodeoxycholic Acid): 250mg per capsule
Choline: 27.5mg per capsule
Suggested Use: As directed by a healthcare practitioner
Total Capsules: 60
Non-Medicinal Ingredients: Hypromellose, magnesium stearate, purified water, silicon dioxide
Consult your healthcare provider to determine the appropriate dosage and duration of use for your individual needs. TUDCA is typically taken with meals to support its role in fat digestion and bile acid physiology.
Who May Consider This Product
• Individuals seeking to help maintain liver function with a naturally occurring bile salt
• Those wanting purified TUDCA in its native taurine-conjugated form
• People wanting a source of choline for liver lipid metabolism support
• Those wanting the TUDCA and choline combination for complementary liver nutritional support
• Individuals interested in the biochemistry of bile acids and the enterohepatic circulation
• Vegans and vegetarians (synthetic TUDCA, not from animal bile)
• Those seeking a Health Canada approved, Canadian-made bile salt supplement
Quality and Purity
• Health Canada approved (NPN 80133303)
• 250mg TUDCA (Tauroursodeoxycholic Acid) per capsule
• 27.5mg choline per capsule
• Purified synthetic TUDCA (not from animal bile)
• Vegan capsules (hypromellose)
• 60 capsules
• Made in Canada in a quality-controlled facility
• 100% vegan and non-GMO
• Gluten-free, dairy-free, soy-free
Storage
Store in a cool, dry place away from direct sunlight. Keep bottle tightly sealed.
Safety Information
Consult a healthcare professional before use if you are pregnant or breastfeeding, taking medications (particularly immunosuppressants, cholesterol-lowering medications, or antacids containing aluminum hydroxide), or have a medical condition including gallstones, bile duct obstruction, or liver disease. TUDCA may interact with antacids containing aluminum hydroxide, which can bind bile salts and reduce their absorption. Do not use without medical supervision if you have bile duct obstruction or acute cholangitis. This product is not intended to diagnose, treat, cure, or prevent any disease.
Keep out of reach of children.
This product is approved by Health Canada (NPN 80133303).
About TUDCA 250mg with Choline | Helps Maintain Liver Function | Source of Choline
TUDCA (Tauroursodeoxycholic Acid) is the taurine conjugate of UDCA, a naturally occurring secondary bile acid, and is the form of UDCA found naturally in human bile. As one of the most water-soluble bile salts in the human bile acid pool, TUDCA is more stable across the pH range of the digestive tract and more resistant to precipitation than unconjugated UDCA. Choline, an essential nutrient, complements TUDCA through its role in phosphatidylcholine synthesis for bile composition and hepatic VLDL export. At 250mg TUDCA and 27.5mg choline per capsule, this formula provides purified, synthetic (non-animal-derived) TUDCA in its native taurine-conjugated form alongside choline. Health Canada approved (NPN 80133303) for helping to maintain liver function and as a source of choline. 100% vegan and made in Canada in a quality-controlled facility.
TUDCA 250mg with Choline | Tauroursodeoxycholic Acid | Purified Conjugated Bile Salt | 60 Vegan Capsules
Each capsule contains 250mg of TUDCA (Tauroursodeoxycholic Acid), a purified taurine-conjugated bile salt that occurs naturally in human bile, and 27.5mg of choline, an essential nutrient involved in liver lipid metabolism and phospholipid synthesis. TUDCA is the taurine conjugate of UDCA (ursodeoxycholic acid), a secondary bile acid naturally present in the human bile acid pool. Helps to maintain liver function. Source of choline. Health Canada approved (NPN 80133303). 100% vegan, non-GMO, gluten-free, and soy-free. Made in Canada in a quality-controlled facility. 60 vegan capsules.
Key Benefits
• Helps to maintain liver function
• Source of choline
• 250mg TUDCA (Tauroursodeoxycholic Acid) per capsule
• Purified taurine-conjugated bile salt naturally occurring in human bile
• 27.5mg choline per capsule
• Choline: essential nutrient for liver lipid metabolism and phospholipid synthesis
• TUDCA + choline for complementary liver nutritional support
• Health Canada approved (NPN 80133303)
• 60 vegan capsules
• Made in Canada in a quality-controlled facility
• 100% vegan and non-GMO
• Gluten-free, dairy-free, soy-free
What Is TUDCA?
TUDCA (Tauroursodeoxycholic Acid) is a bile salt that occurs naturally in the human body as a minor component of the bile acid pool. To understand TUDCA, it helps to understand the bile acid system it belongs to.
Bile Acids and Bile Salts: Bile acids are steroid-derived acids synthesized in the liver from cholesterol. They are the primary organic solutes in bile and are essential for the emulsification and absorption of dietary fats and fat-soluble vitamins in the small intestine. In the liver, bile acids are conjugated with either glycine or taurine to form bile salts, which are more water-soluble and more effective as emulsifying agents than unconjugated bile acids. The human bile acid pool consists of primary bile acids synthesized directly in the liver (cholic acid and chenodeoxycholic acid) and secondary bile acids produced by intestinal bacteria (deoxycholic acid and lithocholic acid), along with their glycine and taurine conjugates.
UDCA (Ursodeoxycholic Acid): UDCA is a secondary bile acid that constitutes a small fraction of the normal human bile acid pool (approximately 1 to 3%). It is also found in significant amounts in bear bile, from which it was first isolated (ursus is Latin for bear). UDCA is a hydrophilic bile acid, in contrast to the more hydrophobic bile acids such as deoxycholic acid and lithocholic acid. This hydrophilic character is significant because hydrophobic bile acids at high concentrations can be damaging to cell membranes, while hydrophilic bile acids are generally better tolerated by cells.
TUDCA (Tauroursodeoxycholic Acid): TUDCA is the taurine conjugate of UDCA — UDCA with a taurine molecule attached at its carboxyl group. Taurine conjugation increases the water solubility of UDCA further, improves its stability in the acidic environment of the stomach, and makes it more resistant to precipitation in bile. TUDCA is the form of UDCA found naturally in human bile and is the predominant form of UDCA in bear bile. As a taurine conjugate, TUDCA is one of the most water-soluble bile salts in the human bile acid pool.
TUDCA vs. UDCA: Why the Taurine Conjugation Matters
Water Solubility: TUDCA is significantly more water-soluble than UDCA due to the taurine conjugation. Greater water solubility means TUDCA remains in solution across a wider range of pH conditions and is less likely to precipitate in bile or the digestive tract.
Gastric Stability: Taurine conjugates are more stable in the acidic environment of the stomach than unconjugated bile acids. UDCA can be partially protonated and precipitate at low pH, while TUDCA's taurine conjugation provides greater stability across the pH range of the digestive tract.
Enterohepatic Circulation: Both TUDCA and UDCA are absorbed from the small intestine and enter the enterohepatic circulation — the recycling pathway by which bile salts are reabsorbed from the terminal ileum, transported back to the liver via the portal vein, and re-secreted into bile. TUDCA's greater water solubility and gastric stability support its absorption and participation in this cycle.
Natural Form: TUDCA is the form of UDCA that occurs naturally in human bile, making it the physiologically native form of this bile acid in the human body.
Bile Acids and the Enterohepatic Circulation
• The liver synthesizes bile acids from cholesterol and conjugates them with glycine or taurine to form bile salts
• Bile salts are secreted into bile and stored in the gallbladder between meals
• After a meal, the gallbladder contracts and releases bile into the duodenum for fat emulsification
• Bile salts emulsify dietary fats, breaking large fat droplets into smaller ones for digestion by pancreatic lipase
• Approximately 95% of bile salts are reabsorbed from the terminal ileum and transported back to the liver via the portal vein
• The liver extracts bile salts from portal blood and re-secretes them into bile, completing the enterohepatic cycle
• The average bile salt molecule undergoes this cycle approximately 4 to 12 times per day
• The approximately 5% of bile salts lost in stool is replaced by new synthesis from cholesterol in the liver
Liver Function Support
The liver is the central organ of bile acid metabolism. It synthesizes primary bile acids from cholesterol, conjugates them with glycine or taurine, secretes them into bile, and extracts them from portal blood during the enterohepatic cycle. TUDCA, as a naturally occurring hydrophilic bile salt, participates in the normal bile acid pool and supports the liver's bile acid handling and secretory function. Health Canada has approved this product (NPN 80133303) for helping to maintain liver function, reflecting the established role of TUDCA in hepatic bile acid physiology.
Choline: Essential Nutrient for Liver Lipid Metabolism
Choline is an essential nutrient recognized by the Institute of Medicine in 1998, required for multiple critical functions with particular importance for liver function and lipid metabolism:
Phosphatidylcholine Synthesis: Choline is the primary building block of phosphatidylcholine, the most abundant phospholipid in cell membranes and a major component of bile. Phosphatidylcholine in bile is essential for the formation of mixed micelles — the structures that solubilize cholesterol and bile salts in bile, preventing their precipitation and crystallization. Adequate choline is therefore important for normal bile composition and the liver's ability to maintain bile fluidity.
VLDL Export from the Liver: Phosphatidylcholine is a required structural component of VLDL (very low-density lipoprotein) particles, the lipoproteins that the liver uses to export triglycerides into the bloodstream. Without adequate choline for phosphatidylcholine synthesis, the liver's ability to export triglycerides as VLDL is impaired, which can lead to triglyceride accumulation in liver cells. Choline is therefore essential for normal hepatic lipid export and liver function.
Methyl Group Donation: Choline is a methyl group donor involved in methylation reactions throughout the body, including the methylation of homocysteine to methionine via betaine (a choline metabolite), connecting choline to the broader one-carbon metabolism network alongside folate and vitamin B12.
TUDCA and Choline Synergy: TUDCA and choline address complementary aspects of liver function. TUDCA contributes to the bile salt component of bile and supports bile flow and fat emulsification. Choline contributes to the phosphatidylcholine component of bile and supports hepatic lipid export via VLDL. Together they provide nutritional support for two distinct but interrelated aspects of liver and biliary function. Health Canada has approved this product (NPN 80133303) as a source of choline.
Understanding the Dosage
TUDCA (Tauroursodeoxycholic Acid): 250mg per capsule
Choline: 27.5mg per capsule
Suggested Use: As directed by a healthcare practitioner
Total Capsules: 60
Non-Medicinal Ingredients: Hypromellose, magnesium stearate, purified water, silicon dioxide
Consult your healthcare provider to determine the appropriate dosage and duration of use for your individual needs. TUDCA is typically taken with meals to support its role in fat digestion and bile acid physiology.
Who May Consider This Product
• Individuals seeking to help maintain liver function with a naturally occurring bile salt
• Those wanting purified TUDCA in its native taurine-conjugated form
• People wanting a source of choline for liver lipid metabolism support
• Those wanting the TUDCA and choline combination for complementary liver nutritional support
• Individuals interested in the biochemistry of bile acids and the enterohepatic circulation
• Vegans and vegetarians (synthetic TUDCA, not from animal bile)
• Those seeking a Health Canada approved, Canadian-made bile salt supplement
Quality and Purity
• Health Canada approved (NPN 80133303)
• 250mg TUDCA (Tauroursodeoxycholic Acid) per capsule
• 27.5mg choline per capsule
• Purified synthetic TUDCA (not from animal bile)
• Vegan capsules (hypromellose)
• 60 capsules
• Made in Canada in a quality-controlled facility
• 100% vegan and non-GMO
• Gluten-free, dairy-free, soy-free
Storage
Store in a cool, dry place away from direct sunlight. Keep bottle tightly sealed.
Safety Information
Consult a healthcare professional before use if you are pregnant or breastfeeding, taking medications (particularly immunosuppressants, cholesterol-lowering medications, or antacids containing aluminum hydroxide), or have a medical condition including gallstones, bile duct obstruction, or liver disease. TUDCA may interact with antacids containing aluminum hydroxide, which can bind bile salts and reduce their absorption. Do not use without medical supervision if you have bile duct obstruction or acute cholangitis. This product is not intended to diagnose, treat, cure, or prevent any disease.
Keep out of reach of children.
This product is approved by Health Canada (NPN 80133303).
About TUDCA 250mg with Choline | Helps Maintain Liver Function | Source of Choline
TUDCA (Tauroursodeoxycholic Acid) is the taurine conjugate of UDCA, a naturally occurring secondary bile acid, and is the form of UDCA found naturally in human bile. As one of the most water-soluble bile salts in the human bile acid pool, TUDCA is more stable across the pH range of the digestive tract and more resistant to precipitation than unconjugated UDCA. Choline, an essential nutrient, complements TUDCA through its role in phosphatidylcholine synthesis for bile composition and hepatic VLDL export. At 250mg TUDCA and 27.5mg choline per capsule, this formula provides purified, synthetic (non-animal-derived) TUDCA in its native taurine-conjugated form alongside choline. Health Canada approved (NPN 80133303) for helping to maintain liver function and as a source of choline. 100% vegan and made in Canada in a quality-controlled facility.
Canadian-Made
Lab-Tested
Health Canada Approved
