Vitamin B12 5,000mcg per Capsule (Methylcobalamin). Active Form. Health Canada Approved (NPN 80070568).

Each capsule contains Vitamin B12 (Methylcobalamin) 5,000mcg. Helps to form red blood cells. Helps in energy metabolism in the body. Helps in the normal function of the immune system. Helps to maintain the body's ability to metabolize nutrients. Health Canada approved (NPN 80070568). Vegan hypromellose capsule. Non-GMO. Made in Canada. 60 capsules. Consult a health care practitioner for use beyond 4 months.

NPN Approved Uses

• Helps to form red blood cells.
• Helps in energy metabolism in the body.
• Helps in the normal function of the immune system.
• Helps to maintain the body's ability to metabolize nutrients.

Key Facts

• Vitamin B12 (Methylcobalamin) 5,000mcg per capsule
• Methylcobalamin — the active form of B12, directly usable without conversion
• High-potency dose: 5,000mcg per capsule
• Health Canada approved (NPN 80070568)
• Vegan hypromellose capsule
• Non-GMO
• 60 capsules
• Made in Canada
• Consult a health care practitioner for use beyond 4 months

What This Product Does

This formula helps to form red blood cells. It helps in energy metabolism in the body. It helps in the normal function of the immune system. It helps to maintain the body's ability to metabolize nutrients. These are the Health Canada approved uses (NPN 80070568). This product is not intended to diagnose, treat, cure, or prevent any disease.

What Is Vitamin B12?

Vitamin B12 (cobalamin) is an essential water-soluble vitamin. It is the largest and most structurally complex of all the vitamins. B12 is unique among vitamins in that it contains a metal ion cobalt at its centre, which is why it is called cobalamin. B12 is found almost exclusively in animal-derived foods: meat, fish, shellfish, dairy products, and eggs. Plant foods do not contain meaningful amounts of bioavailable B12. This makes B12 supplementation particularly important for vegans and vegetarians.

B12 is required for DNA synthesis, red blood cell formation, and the normal function of the nervous system. It works closely with folate (B9) in one-carbon metabolism. B12 deficiency can develop slowly over months to years because the liver stores a reserve of B12. Early deficiency may not produce obvious symptoms, which is why regular monitoring is important for those at risk.

Methylcobalamin: The Active Form of B12

There are four forms of vitamin B12: methylcobalamin, adenosylcobalamin, hydroxocobalamin, and cyanocobalamin. Methylcobalamin and adenosylcobalamin are the two active coenzyme forms found in human cells. Cyanocobalamin is a synthetic form used in most B12 supplements and fortified foods. It must be converted to methylcobalamin or adenosylcobalamin in the body before it can be used, and this conversion releases a small amount of cyanide (at non-toxic levels).

Methylcobalamin is the active form found in human blood and tissues. It is directly usable by the body without conversion. This formula uses methylcobalamin exclusively.

Why 5,000mcg? Understanding B12 Absorption

B12 is absorbed through two distinct mechanisms in the digestive system.

Primary mechanism — Intrinsic factor (IF) mediated absorption: Intrinsic factor is a protein produced by the parietal cells of the stomach lining. B12 binds to intrinsic factor in the stomach, and the B12-IF complex is then absorbed in the terminal ileum (the last section of the small intestine). This mechanism is highly efficient but saturable: it can absorb a maximum of approximately 1.5 to 2mcg of B12 per meal, regardless of how much B12 is consumed. Intrinsic factor production can be impaired by aging, autoimmune conditions (pernicious anemia), gastric surgery, atrophic gastritis, and long-term use of proton pump inhibitors or H2 blockers.

Secondary mechanism — Passive diffusion: Approximately 1% of any oral B12 dose is absorbed by passive diffusion across the intestinal lining, independent of intrinsic factor. This mechanism does not saturate. At 5,000mcg, passive diffusion alone absorbs approximately 50mcg of B12 a meaningful amount that does not depend on intrinsic factor function.

The high dose of 5,000mcg ensures that even people with reduced intrinsic factor production can absorb a useful amount of B12 through passive diffusion. For people with normal intrinsic factor function, the intrinsic factor mechanism absorbs the first 1.5 to 2mcg efficiently, and passive diffusion adds approximately 50mcg on top of that.

Who May Consider a Standalone High-Dose B12 Supplement

• Vegans and vegetarians (B12 is found almost exclusively in animal-derived foods)
• Older adults (intrinsic factor production declines with age, reducing B12 absorption from food)
• People taking metformin (metformin reduces B12 absorption in the intestine)
• People taking proton pump inhibitors or H2 blockers long-term (reduce stomach acid needed to release B12 from food proteins)
• People with confirmed low B12 levels who want a high-potency oral supplement
• Those who want methylcobalamin (active form) rather than cyanocobalamin

Consult a health care practitioner prior to use if you are pregnant or breastfeeding, or if you have diabetes. Consult a health care practitioner for use beyond 4 months.

B12 and Vegans

Vitamin B12 is found almost exclusively in animal derived foods. Fermented plant foods, algae, and some plant foods contain B12 analogues, but these are generally not bioavailable in the same way as B12 from animal sources and may even interfere with B12 absorption. Supplementation is the recommended approach for vegans and vegetarians to maintain adequate B12 status. This formula uses a vegan hypromellose capsule and contains no animal-derived ingredients.

Understanding the Ingredient Content

Vitamin B12 (Methylcobalamin): 5,000mcg per capsule
Suggested Use: Verify the recommended dose from NPN 80070568 licence and add here before publishing.
Capsules per bottle: 60
Duration of use: Consult a health care practitioner for use beyond 4 months.
Non Medicinal Ingredients: Magnesium Stearate, Hypromellose (Capsule Shell)

Quality and Purity

• Health Canada approved (NPN 80070568)
• Vitamin B12 (Methylcobalamin) 5,000mcg per capsule
• Vegan hypromellose capsule shell
• Non-GMO
• 60 capsules
• Made in Canada

Storage

Store in a cool, dry place away from direct sunlight and moisture. Keep bottle tightly sealed after each use.

Safety Information and Cautions

Consult a health care practitioner prior to use if you are pregnant or breastfeeding, or if you have diabetes.

Consult a health care practitioner for use beyond 4 months.

This product is not intended to diagnose, treat, cure, or prevent any disease.

Keep out of reach of children.

About This Product

What it is: Vitamin B12 (Methylcobalamin) 5,000mcg per capsule. Single ingredient. Vegan hypromellose capsule. 60 capsules.

What it does: Helps to form red blood cells. Helps in energy metabolism in the body. Helps in the normal function of the immune system. Helps to maintain the body's ability to metabolize nutrients (NPN 80070568).

Why 5,000mcg: B12 is absorbed via two mechanisms intrinsic factor (saturable at ~1.5 to 2mcg per meal) and passive diffusion (~1% of dose). At 5,000mcg, passive diffusion alone absorbs approximately 50mcg, making this dose effective even for people with reduced intrinsic factor function. Methylcobalamin is the active form found in human blood and tissues, directly usable without conversion.

Who it’s for: Adults. Particularly relevant for vegans and vegetarians, older adults, people taking metformin or proton pump inhibitors, and those with confirmed low B12 levels. Consult a health care practitioner before use if pregnant, breastfeeding, or diabetic. Consult a health care practitioner for use beyond 4 months.

Where it’s made: Canada. Non-GMO. Health Canada approved (NPN 80070568).