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Alpha Lipoic Acid 600mg | DL-ALA | Antioxidant and Metabolism Support | 120 Vegan Capsules

Each capsule delivers 600mg of DL-alpha-lipoic acid (DL-ALA), the racemic mixture of R-ALA (the naturally occurring biologically active enantiomer) and S-ALA (50:50). Alpha-lipoic acid is a sulfur-containing fatty acid that functions as both an essential mitochondrial enzyme cofactor and a universal antioxidant active in both aqueous and lipid environments. Antioxidant. Helps support glucose metabolism. A factor in the maintenance of good health. Health Canada approved (NPN 80122537). 100% vegan, non GMO, gluten free, soy free, dairy free, corn free. Made in Canada in a GMP certified, third party lab tested facility. 120 vegan capsules (120 day supply at 1 capsule per day).

Stop use and consult a health care practitioner if you experience sweating, paleness, chills, headache, dizziness and/or confusion, as these may be symptoms of serious low blood sugar.

Key Features

• Antioxidant
• Helps support glucose metabolism
• A factor in the maintenance of good health
• 600mg DL-alpha-lipoic acid per capsule (50% R-ALA, 50% S-ALA)
• Universal antioxidant: active in both aqueous and lipid environments
• Regenerates vitamin C, vitamin E, and glutathione
• Chelates pro-oxidant metal ions (copper, iron, cadmium, mercury)
• Essential cofactor for pyruvate dehydrogenase and alpha-ketoglutarate dehydrogenase complexes
• Supports glucose uptake via AMPK activation and GLUT4 translocation
• 1 capsule per day: 120 day supply
• Health Canada approved (NPN 80122537)
• Made in Canada in a GMP certified, third party lab tested facility
• 100% vegan and non GMO
• Gluten free, soy free, dairy free, corn free

DL-ALA: The Racemic Form

Alpha-lipoic acid has one chiral center, producing two enantiomers: R-ALA (naturally occurring, the form used as a mitochondrial enzyme cofactor) and S-ALA (synthetic). DL-ALA is the 50:50 racemic mixture of both. At 600mg DL-ALA per capsule, the formula provides approximately 300mg of the biologically active R-ALA enantiomer. DL-ALA is more chemically stable and more cost-effective than pure R-ALA and is the most widely studied form in clinical research.

Antioxidant Mechanisms

ALA is reduced to dihydrolipoic acid (DHLA) by lipoamide dehydrogenase. The ALA/DHLA redox couple is active in both aqueous and lipid cellular environments, unlike vitamin C (aqueous only) or vitamin E (lipid only). DHLA directly scavenges reactive oxygen species and regenerates the antioxidant network: DHLA reduces dehydroascorbate back to vitamin C, vitamin C reduces the tocopheroxyl radical back to vitamin E, and DHLA reduces oxidized glutathione (GSSG) back to reduced glutathione (GSH). ALA also chelates pro-oxidant metal ions including copper, iron, cadmium, and mercury, reducing their ability to catalyze free radical generation via the Fenton reaction.

Mitochondrial Cofactor and Glucose Metabolism

In its endogenous role, ALA is covalently bound to the E2 subunit of the pyruvate dehydrogenase complex (PDC, which converts pyruvate to acetyl-CoA, linking glycolysis to the citric acid cycle) and the alpha-ketoglutarate dehydrogenase complex (KGDC, a step within the citric acid cycle). At supplemental doses, free ALA activates AMPK (AMP-activated protein kinase), promoting GLUT4 glucose transporter translocation to the cell surface in muscle and adipose tissue and enhancing insulin-stimulated glucose uptake. This glucose-lowering effect is the basis for the diabetes caution and the hypoglycemia stop-use warning.

Dosage and Supply

DL-alpha-Lipoic acid: 600mg per capsule
Suggested Use: Adults: 1 capsule, 1 time per day
Total Capsules: 120 (120 day supply)
Non Medicinal Ingredients: Microcrystalline cellulose, Silicon dioxide, Hypromellose (vegetable capsule)

Consult your healthcare provider to determine the appropriate dosage and duration of use for your individual needs.

Who May Consider This Product

• Adults seeking antioxidant support from a universal antioxidant active in both aqueous and lipid environments
• Those wanting support for glucose metabolism
• Those wanting an antioxidant that regenerates vitamin C, vitamin E, and glutathione
• Those wanting a 120 day supply at 1 capsule per day
• Those wanting a clean formula: vegan, non GMO, gluten free, soy free, dairy free, corn free
• Those seeking a Health Canada approved, Canadian made, third party lab tested ALA supplement

Quality and Purity

• Health Canada approved (NPN 80122537)
• 600mg DL-alpha-lipoic acid per capsule
• Vegan hypromellose capsule
• 120 capsules (120 day supply)
• Made in Canada in a GMP certified facility
• Third party lab tested
• 100% vegan and non GMO
• Gluten free, soy free, dairy free, corn free

Storage

Store in a cool, dry place away from direct sunlight. Keep bottle tightly sealed after each use. Alpha-lipoic acid is sensitive to heat and light; avoid storing in warm or humid conditions.

Safety Information and Cautions

Stop use and consult a health care practitioner if you experience sweating, paleness, chills, headache, dizziness and/or confusion, as these may be symptoms of serious low blood sugar.

Consult a health care practitioner prior to use if you are pregnant, breastfeeding, or have diabetes, as ALA's glucose metabolism effects can lower blood sugar and may interact with diabetes medications. This product is not intended to diagnose, treat, cure, or prevent any disease.

Keep out of reach of children.

This product is approved by Health Canada (NPN 80122537).

About Alpha Lipoic Acid 600mg | DL-ALA | Antioxidant and Metabolism Support | 120 Vegan Capsules

DL-alpha-lipoic acid 600mg per capsule (50% R-ALA, 50% S-ALA). Universal antioxidant active in both aqueous and lipid environments: DHLA regenerates vitamin C, vitamin E, and glutathione, and chelates pro-oxidant metal ions. Essential mitochondrial cofactor for the pyruvate dehydrogenase and alpha-ketoglutarate dehydrogenase complexes. Supports glucose metabolism via AMPK activation and GLUT4 translocation. Stop use if symptoms of low blood sugar occur. Consult a healthcare practitioner before use if pregnant, breastfeeding, or diabetic. Health Canada approved (NPN 80122537). 100% vegan and made in Canada in a GMP certified, third party lab tested facility. 120 capsules, 120 day supply at 1 capsule per day.

Alpha Lipoic Acid 600mg | DL-ALA | Antioxidant | Metabolism Support | 120 Vcaps

Regular price $23.70
Unit price
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Health Canada Licensed Natural Health Product (NPN 80122537)

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Alpha Lipoic Acid 600mg | DL-ALA | Antioxidant and Metabolism Support | 120 Vegan Capsules

Each capsule delivers 600mg of DL-alpha-lipoic acid (DL-ALA), the racemic mixture of R-ALA (the naturally occurring biologically active enantiomer) and S-ALA (50:50). Alpha-lipoic acid is a sulfur-containing fatty acid that functions as both an essential mitochondrial enzyme cofactor and a universal antioxidant active in both aqueous and lipid environments. Antioxidant. Helps support glucose metabolism. A factor in the maintenance of good health. Health Canada approved (NPN 80122537). 100% vegan, non GMO, gluten free, soy free, dairy free, corn free. Made in Canada in a GMP certified, third party lab tested facility. 120 vegan capsules (120 day supply at 1 capsule per day).

Stop use and consult a health care practitioner if you experience sweating, paleness, chills, headache, dizziness and/or confusion, as these may be symptoms of serious low blood sugar.

Key Features

• Antioxidant
• Helps support glucose metabolism
• A factor in the maintenance of good health
• 600mg DL-alpha-lipoic acid per capsule (50% R-ALA, 50% S-ALA)
• Universal antioxidant: active in both aqueous and lipid environments
• Regenerates vitamin C, vitamin E, and glutathione
• Chelates pro-oxidant metal ions (copper, iron, cadmium, mercury)
• Essential cofactor for pyruvate dehydrogenase and alpha-ketoglutarate dehydrogenase complexes
• Supports glucose uptake via AMPK activation and GLUT4 translocation
• 1 capsule per day: 120 day supply
• Health Canada approved (NPN 80122537)
• Made in Canada in a GMP certified, third party lab tested facility
• 100% vegan and non GMO
• Gluten free, soy free, dairy free, corn free

DL-ALA: The Racemic Form

Alpha-lipoic acid has one chiral center, producing two enantiomers: R-ALA (naturally occurring, the form used as a mitochondrial enzyme cofactor) and S-ALA (synthetic). DL-ALA is the 50:50 racemic mixture of both. At 600mg DL-ALA per capsule, the formula provides approximately 300mg of the biologically active R-ALA enantiomer. DL-ALA is more chemically stable and more cost-effective than pure R-ALA and is the most widely studied form in clinical research.

Antioxidant Mechanisms

ALA is reduced to dihydrolipoic acid (DHLA) by lipoamide dehydrogenase. The ALA/DHLA redox couple is active in both aqueous and lipid cellular environments, unlike vitamin C (aqueous only) or vitamin E (lipid only). DHLA directly scavenges reactive oxygen species and regenerates the antioxidant network: DHLA reduces dehydroascorbate back to vitamin C, vitamin C reduces the tocopheroxyl radical back to vitamin E, and DHLA reduces oxidized glutathione (GSSG) back to reduced glutathione (GSH). ALA also chelates pro-oxidant metal ions including copper, iron, cadmium, and mercury, reducing their ability to catalyze free radical generation via the Fenton reaction.

Mitochondrial Cofactor and Glucose Metabolism

In its endogenous role, ALA is covalently bound to the E2 subunit of the pyruvate dehydrogenase complex (PDC, which converts pyruvate to acetyl-CoA, linking glycolysis to the citric acid cycle) and the alpha-ketoglutarate dehydrogenase complex (KGDC, a step within the citric acid cycle). At supplemental doses, free ALA activates AMPK (AMP-activated protein kinase), promoting GLUT4 glucose transporter translocation to the cell surface in muscle and adipose tissue and enhancing insulin-stimulated glucose uptake. This glucose-lowering effect is the basis for the diabetes caution and the hypoglycemia stop-use warning.

Dosage and Supply

DL-alpha-Lipoic acid: 600mg per capsule
Suggested Use: Adults: 1 capsule, 1 time per day
Total Capsules: 120 (120 day supply)
Non Medicinal Ingredients: Microcrystalline cellulose, Silicon dioxide, Hypromellose (vegetable capsule)

Consult your healthcare provider to determine the appropriate dosage and duration of use for your individual needs.

Who May Consider This Product

• Adults seeking antioxidant support from a universal antioxidant active in both aqueous and lipid environments
• Those wanting support for glucose metabolism
• Those wanting an antioxidant that regenerates vitamin C, vitamin E, and glutathione
• Those wanting a 120 day supply at 1 capsule per day
• Those wanting a clean formula: vegan, non GMO, gluten free, soy free, dairy free, corn free
• Those seeking a Health Canada approved, Canadian made, third party lab tested ALA supplement

Quality and Purity

• Health Canada approved (NPN 80122537)
• 600mg DL-alpha-lipoic acid per capsule
• Vegan hypromellose capsule
• 120 capsules (120 day supply)
• Made in Canada in a GMP certified facility
• Third party lab tested
• 100% vegan and non GMO
• Gluten free, soy free, dairy free, corn free

Storage

Store in a cool, dry place away from direct sunlight. Keep bottle tightly sealed after each use. Alpha-lipoic acid is sensitive to heat and light; avoid storing in warm or humid conditions.

Safety Information and Cautions

Stop use and consult a health care practitioner if you experience sweating, paleness, chills, headache, dizziness and/or confusion, as these may be symptoms of serious low blood sugar.

Consult a health care practitioner prior to use if you are pregnant, breastfeeding, or have diabetes, as ALA's glucose metabolism effects can lower blood sugar and may interact with diabetes medications. This product is not intended to diagnose, treat, cure, or prevent any disease.

Keep out of reach of children.

This product is approved by Health Canada (NPN 80122537).

About Alpha Lipoic Acid 600mg | DL-ALA | Antioxidant and Metabolism Support | 120 Vegan Capsules

DL-alpha-lipoic acid 600mg per capsule (50% R-ALA, 50% S-ALA). Universal antioxidant active in both aqueous and lipid environments: DHLA regenerates vitamin C, vitamin E, and glutathione, and chelates pro-oxidant metal ions. Essential mitochondrial cofactor for the pyruvate dehydrogenase and alpha-ketoglutarate dehydrogenase complexes. Supports glucose metabolism via AMPK activation and GLUT4 translocation. Stop use if symptoms of low blood sugar occur. Consult a healthcare practitioner before use if pregnant, breastfeeding, or diabetic. Health Canada approved (NPN 80122537). 100% vegan and made in Canada in a GMP certified, third party lab tested facility. 120 capsules, 120 day supply at 1 capsule per day.

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