Extra Strength Cognitive Support Formula
Nutridom Ginkgo Biloba delivers 12,000mg Qualified Crude Equivalent (QCE) per capsule from a concentrated 50:1 extract standardized to 24% flavonoid glycosides and 6% terpene lactones. This pharmaceutical grade formulation provides the bioactive compounds extensively studied for cognitive function, memory support, and healthy circulation. 60 vegan capsules per bottle.

Standardized Active Compounds

• 12,000mg QCE per capsule (50:1 concentrated extract)
• 24% flavonoid glycosides (quercetin, kaempferol, isorhamnetin)
• 6% terpene lactones (ginkgolides A, B, C and bilobalide)
• Supports cerebral blood flow and brain oxygenation
• Provides antioxidant protection for neural tissue

Evidence Based Cognitive Mechanisms

• Supports healthy cerebral circulation and microvascular function
• Promotes neurotransmitter activity and synaptic function
• Aids antioxidant defense in brain tissue
• Supports memory formation and cognitive processing
• Promotes healthy inflammatory response in neural tissue

Pharmaceutical Grade Quality

• Standardized Ginkgo biloba leaf extract (EGb 761 equivalent)
• 50:1 concentration ratio for maximum potency
• Third party tested for purity and active compound content
• Manufactured in Canada under GMP certification
• Vegan capsules, Non-GMO, gluten free, soy free, dairy free

Optimal Dosing Protocol

• Take 1 capsule daily with meals
• Consistent daily use for cumulative cognitive benefits
• Allow 4 to 6 weeks for optimal effects
• Supports sustained brain health and circulation
• May be taken long term for ongoing support

Scientifically Formulated For

• Adults seeking cognitive function and memory support
• Individuals supporting healthy brain aging
• Those focused on mental clarity and focus
• People supporting cerebral circulation
• Health conscious consumers preferring evidence based botanicals

What is Ginkgo Biloba?

Ginkgo biloba is one of the oldest living tree species, dating back over 200 million years. The fan shaped leaves contain unique bioactive compounds including flavonoid glycosides and terpene lactones. Ginkgo has been used in traditional Chinese medicine for thousands of years and is now one of the most extensively researched botanical supplements for cognitive health and circulation support.

Understanding the 50:1 Extract and 12,000mg QCE

The 50:1 concentration ratio means 50 kilograms of dried ginkgo leaves are processed to produce 1 kilogram of concentrated extract. Each capsule provides 240mg of this concentrated extract, equivalent to 12,000mg of raw dried leaves (Qualified Crude Equivalent or QCE). This concentration process removes inactive components while preserving and concentrating the beneficial flavonoids and terpenes.

What are Flavonoid Glycosides?

Flavonoid glycosides are polyphenolic compounds that provide antioxidant and vascular benefits. Ginkgo contains several flavonoids including:

• Quercetin: Potent antioxidant supporting vascular health
• Kaempferol: Supports healthy inflammatory response
• Isorhamnetin: Provides neuroprotective properties
• Rutin: Supports capillary integrity and strength

The 24% standardization ensures consistent flavonoid content in every capsule, matching levels used in clinical research.

What are Terpene Lactones?

Terpene lactones are unique compounds found exclusively in ginkgo biloba. The two main categories are:

• Ginkgolides (A, B, C, J): Support platelet activating factor (PAF) modulation
• Bilobalide: Supports mitochondrial function and neuroprotection

The 6% terpene standardization provides the bioactive compounds responsible for many of ginkgo's cognitive and circulatory benefits.

Clinical Research on Ginkgo Biloba

Ginkgo biloba is one of the most extensively studied botanical supplements with over 400 clinical trials. Research published in peer reviewed journals demonstrates ginkgo's effects on cognitive function, memory, cerebral blood flow, and antioxidant activity. The standardized extract EGb 761 (similar to our formulation) has been used in numerous studies showing benefits for cognitive performance, particularly in older adults.

How Ginkgo Supports Brain Function

Ginkgo biloba supports cognitive health through multiple mechanisms:

• Cerebral circulation: Promotes blood flow to the brain
• Microvascular function: Supports small vessel health in brain tissue
• Neurotransmitter activity: Influences acetylcholine, dopamine, and serotonin
• Antioxidant protection: Scavenges free radicals in neural tissue
• Mitochondrial support: Aids cellular energy production in neurons
• Neuroprotection: Supports healthy brain cell function and longevity

Memory and Cognitive Performance

Research indicates ginkgo may support various aspects of cognitive function:

• Working memory: Supports short term information processing
• Long term memory: Aids memory formation and recall
• Processing speed: Supports mental quickness and reaction time
• Attention and focus: Promotes sustained concentration
• Executive function: Supports planning and decision making

Effects are typically most pronounced with consistent use over 4 to 12 weeks.

Cerebral Circulation and Blood Flow

Ginkgo's effects on circulation are well documented:

• Vasodilation: Promotes healthy blood vessel relaxation
• Microcirculation: Supports blood flow in small capillaries
• Blood viscosity: May support healthy blood flow properties
• Oxygen delivery: Aids oxygen transport to brain tissue
• Nutrient supply: Supports glucose and nutrient delivery to neurons

Antioxidant and Neuroprotective Properties

Ginkgo provides robust antioxidant protection for brain tissue:

• Free radical scavenging: Neutralizes reactive oxygen species
• Lipid peroxidation: Protects cell membranes from oxidative damage
• Mitochondrial protection: Supports cellular energy production
• DNA protection: Shields genetic material from oxidative stress
• Protein protection: Prevents oxidative protein modification

Platelet Activating Factor (PAF) Modulation

Ginkgolides uniquely modulate platelet activating factor (PAF), a signaling molecule involved in:

• Platelet aggregation and blood clotting
• Inflammatory responses
• Allergic reactions
• Vascular permeability
• Neurotransmitter release

By modulating PAF, ginkgo supports healthy inflammatory balance and vascular function.

Age Related Cognitive Decline

Ginkgo has been extensively studied for supporting healthy brain aging:

• Supports cognitive function in older adults
• May help maintain memory with aging
• Supports healthy cerebral blood flow that declines with age
• Provides antioxidant protection against age related oxidative stress
• Supports mitochondrial function in aging neurons

Neurotransmitter Support

Ginkgo influences several neurotransmitter systems:

• Acetylcholine: Supports memory and learning processes
• Dopamine: Influences motivation and cognitive flexibility
• Serotonin: Affects mood and cognitive function
• GABA: Supports calm focus and mental balance
• Norepinephrine: Influences attention and alertness

Peripheral Circulation Benefits

Beyond brain health, ginkgo supports circulation throughout the body:

• Leg circulation: Supports blood flow to extremities
• Eye health: Promotes retinal and ocular circulation
• Ear function: Supports cochlear blood flow
• Skin health: Aids peripheral microcirculation
• Overall vitality: Supports tissue oxygenation

Standardization and Quality

Pharmaceutical grade ginkgo requires precise standardization:

• 24% flavonoid glycosides: Verified by HPLC analysis
• 6% terpene lactones: Confirmed by chromatography
• Less than 5 ppm ginkgolic acids: Removes potentially irritating compounds
• Consistent potency: Every batch meets specifications
• Quality testing: Third party verification of purity and content

EGb 761 Equivalent Formulation

Our formulation mirrors EGb 761, the most researched ginkgo extract:

• Same standardization: 24% flavonoids, 6% terpenes
• Similar processing: Acetone water extraction method
• Comparable quality: Pharmaceutical grade standards
• Research backed: Formulation used in clinical studies

Dosing and Timeline

Evidence based dosing recommendations:

• Standard dose: 120 to 240mg extract daily (1 to 2 capsules)
• Our formula: 240mg extract (12,000mg QCE) per capsule
• Timing: Take with meals for optimal absorption
• Duration: Allow 4 to 6 weeks for initial benefits
• Optimal results: 8 to 12 weeks of consistent use
• Long term: Safe for ongoing daily supplementation

Complementary Nutrients

Nutrients that work synergistically with ginkgo:

• Phosphatidylserine: Supports memory and cognitive function
• Bacopa monnieri: Complementary cognitive support
• Omega-3 fatty acids: Brain structure and function
• B vitamins: Energy metabolism and neurotransmitter synthesis
• Vitamin E: Additional antioxidant protection
• CoQ10: Mitochondrial energy support

Who Should Use Ginkgo Biloba?

Ideal for:

• Adults over 40 supporting healthy brain aging
• Individuals seeking memory and focus support
• Those supporting cerebral circulation
• People interested in cognitive performance optimization
• Anyone seeking antioxidant support for brain health
• Individuals supporting overall vascular wellness

Expected Timeline for Results

Typical experience timeline:

• Weeks 1 to 2: Initial subtle improvements may be noticed
• Weeks 4 to 6: More consistent cognitive benefits emerge
• Weeks 8 to 12: Optimal effects with daily use
• Long term: Sustained support for brain health and function
• Individual variation: Some respond faster than others

Safety and Considerations

Ginkgo biloba has a favorable safety profile in clinical studies. However, important considerations include:

Consult healthcare provider before use if:

• Taking blood thinning medications (warfarin, aspirin, clopidogrel)
• Scheduled for surgery (discontinue 2 weeks prior)
• Taking antidepressant medications (potential interactions)
• Have bleeding disorders or clotting issues
• Pregnant, nursing, or planning pregnancy
• Have seizure disorders (consult physician)

Optimal use guidelines:

• Take with meals for best absorption
• Maintain consistent daily supplementation
• Allow adequate time for cumulative benefits (4 to 12 weeks)
• Combine with healthy lifestyle for best results
• Support with balanced diet rich in antioxidants
• Stay mentally active with cognitive challenges

*These statements have not been evaluated by Health Canada or the FDA. This product is not intended to diagnose, treat, cure, or prevent any disease.