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Haute qualité
La curcumine fortifiée Nutridom offre un mélange de qualité supérieure d'extrait de curcumine associé à de la pipérine (issue du poivre noir) pour favoriser une meilleure absorption. La curcumine, composé actif du curcuma, est reconnue pour ses propriétés antioxydantes naturelles et son rôle dans la médecine traditionnelle à base de plantes.

Soutien antioxydant naturel
La curcumine est largement reconnue pour son activité antioxydante, aidant l'organisme à gérer le stress oxydatif lié aux activités quotidiennes. Cette formule est idéale pour les personnes recherchant une source végétale concentrée d'antioxydants à intégrer à leur routine quotidienne.

Biodisponibilité améliorée grâce à la pipérine
La pipérine est couramment utilisée dans les préparations à base de plantes pour favoriser l'absorption des nutriments. Associée à la curcumine, elle contribue à une meilleure assimilation de cet extrait végétal.

Curcumine Nutridom avec pipérine | Absorption améliorée | 60 gélules végétales

Prix normal $28.50
Prix ​​à l'unité
Par 
5.0 (2)

Health Canada Licensed Natural Health Product (NPN 80068970)

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Haute qualité
La curcumine fortifiée Nutridom offre un mélange de qualité supérieure d'extrait de curcumine associé à de la pipérine (issue du poivre noir) pour favoriser une meilleure absorption. La curcumine, composé actif du curcuma, est reconnue pour ses propriétés antioxydantes naturelles et son rôle dans la médecine traditionnelle à base de plantes.

Soutien antioxydant naturel
La curcumine est largement reconnue pour son activité antioxydante, aidant l'organisme à gérer le stress oxydatif lié aux activités quotidiennes. Cette formule est idéale pour les personnes recherchant une source végétale concentrée d'antioxydants à intégrer à leur routine quotidienne.

Biodisponibilité améliorée grâce à la pipérine
La pipérine est couramment utilisée dans les préparations à base de plantes pour favoriser l'absorption des nutriments. Associée à la curcumine, elle contribue à une meilleure assimilation de cet extrait végétal.

Supplement Facts

Supplement Facts

Serving Size: 1 Capsule

Servings Per Container: 60

Ingredient
Amount Per
Serving
% Daily
Value
Curcumin (Curcuma longa, Rhizome)
400 mg
Black Pepper Extract (Piper nigrum, Fruit, 2:1, QCE 160mg)
80 mg

† Daily Value not established

Other Ingredients:
Hypromellose (Vegetable Capsule Shell), Magnesium Stearate

Clinical Research

Piperine Enhancement of Curcumin Bioavailability A Pharmacokinetic Study in Healthy Human Volunteers

Planta Medica, 1998

This pharmacokinetic study examined the effect of piperine co-administration on the oral bioavailability of curcumin in healthy human volunteers. The study documented that co-administration of 20mg of piperine with 2,000mg of curcumin produced a 2,000% increase in curcumin bioavailability compared to curcumin alone, as measured by serum curcumin levels and area under the curve (AUC). The authors attributed the enhancement to piperine's inhibition of intestinal and hepatic CYP3A4 and P-glycoprotein, which are the primary mechanisms responsible for curcumin's rapid first-pass elimination. The authors concluded that piperine is a highly effective bioavailability enhancer for curcumin and that co-formulation is the standard approach for oral curcumin supplementation.

Curcumin (Curcuma longa) and Joint Inflammation A Systematic Review of Clinical Evidence

Journal of Medicinal Food, 2016

This systematic review examined the clinical evidence for curcumin supplementation in the relief of joint inflammation in adults. The review analyzed data from multiple randomized controlled trials and documented that curcumin supplementation was associated with statistically significant reductions in joint inflammation markers and improvements in joint comfort and mobility compared to placebo. The authors noted that studies using bioavailability-enhanced curcumin formulations including piperine co administration consistently showed stronger effects than studies using plain curcumin, consistent with the known bioavailability limitations of oral curcumin. The authors concluded that curcumin is a well supported herbal medicine remedy for joint inflammation relief.

Piperine Inhibition of CYP3A4 and P-Glycoprotein Mechanism and Drug Interaction Implications

Drug Metabolism and Disposition, 2002

This study examined the mechanism by which piperine enhances the bioavailability of co administered compounds, focusing on its inhibition of CYP3A4 and P-glycoprotein in intestinal and hepatic tissue. The study documented that piperine is a potent inhibitor of both CYP3A4 and P-glycoprotein at doses consistent with supplemental use, and that this inhibition significantly reduces the first pass elimination of compounds that are substrates for these pathways including curcumin. The authors noted that the same mechanism that enhances curcumin bioavailability also applies to many pharmaceutical drugs that use CYP3A4 and P-glycoprotein for metabolism and elimination, which is the basis for the drug interaction caution associated with piperine containing supplements.

Research information is provided for educational purposes and does not replace the product's approved label information.

Frequently Asked Questions

Why is piperine added to curcumin supplements?

Curcumin has poor oral bioavailability due to rapid metabolism by CYP3A4 enzymes and efflux by P-glycoprotein transporters in the gut and liver. Piperine, the active alkaloid in black pepper, inhibits both pathways, reducing curcumin breakdown and significantly increasing the amount absorbed into systemic circulation.

What does "2:1 extract, QCE 160 mg" mean on the label?

QCE (Quantity of Crude Equivalent) is a Health Canada labelling standard. A 2:1 Black Pepper extract means 80 mg of concentrated extract was derived from 160 mg of raw black pepper fruit, ensuring a standardized and consistent Piperine dose of 4 mg per capsule.

What is the difference between turmeric and curcumin?

Turmeric (Curcuma longa) is the whole dried rhizome used as a spice. Curcumin is the primary polyphenolic curcuminoid extracted from turmeric, comprising approximately 2–5% of the dried root by weight. Standardized curcumin supplements deliver a concentrated dose not achievable through dietary turmeric alone.

How does curcumin support joint health?

Curcumin has been shown in clinical research to inhibit pro inflammatory mediators including NF-κB, COX-2, and various cytokines involved in joint inflammation. One randomized controlled trial found curcumin comparable to ibuprofen for knee osteoarthritis pain during walking and stair climbing, with fewer gastrointestinal side effects

Who is Curcumin with Piperine suitable for?

Adults seeking a Herbal Medicine remedy to help relieve joint inflammation using curcumin from turmeric rhizome with piperine from black pepper for enhanced absorption. Vegan, non-GMO, gluten free, and dairy free. Not suitable for those taking antiplatelet medications, blood thinners, or other medications without first consulting a healthcare practitioner, as piperine may alter their effectiveness.

Why is Curcumin with Piperine more effective than plain curcumin supplements?

Plain curcumin supplements without piperine have very low oral bioavailability most of the dose is broken down by CYP3A4 and pumped back into the gut by P-glycoprotein before it can be absorbed. Piperine inhibits both pathways, significantly increasing the amount of curcumin that reaches systemic circulation. A curcumin supplement without piperine delivers far less active curcumin to the body than the same dose with piperine.