달맞이꽃종자유 500mg | 냉압착 | GLA 10% | 천연 오메가 6 | 200 소프트젤

Evening Primrose Oil (EPO) is a cold pressed oil extracted from the seeds ofOenothera biennis the evening primrose plant native to North America. It is one of the richest plant sources of gamma-linolenic acid (GLA), a conditionally essential omega-6 fatty acid not widely found in the diet. GLA supports skin barrier function, hormonal balance, and healthy inflammatory response through the GLA → DGLA → Prostaglandin E1 pathway.

Gamma-linolenic acid (GLA) is a conditionally essential omega-6 fatty acid that the body synthesizes from dietary linoleic acid via the delta-6-desaturase enzyme. It is "conditionally essential" because this enzymatic conversion is routinely impaired by aging, chronic stress, insulin resistance, alcohol consumption, and hormonal fluctuations meaning many adults cannot produce adequate GLA from diet alone even with sufficient linoleic acid intake. GLA is the precursor to dihomo-gamma linolenic acid (DGLA) and prostaglandin E1 (PGE1) a Series 1 prostaglandin that supports healthy inflammatory balance, skin barrier integrity, and hormonal signalling. Evening primrose oil delivers GLA directly, bypassing the delta-6-desaturase enzymatic step entirely.

GLA is incorporated into ceramides and phospholipids that form the skin lipid barrier the lamellar structure between corneocytes that governs transepidermal water loss (TEWL) and barrier integrity. GLA deficiency is associated with increased TEWL, dry skin, reduced elasticity, and impaired barrier function. Evening primrose oil supplementation supports ceramide synthesis and barrier repair, improving skin hydration and elasticity from within. The skin barrier benefit of GLA is distinct from topical moisturizers it works by restoring the structural lipid composition of the barrier at the cellular level through oral supplementation.

DGLA the elongation product of GLA is a precursor to prostaglandin E1 (PGE1) and to 15-HETrE, both of which modulate estrogen sensitive tissue responses and luteal phase signalling. This prostaglandin pathway is the mechanism through which evening primrose oil supports premenstrual comfort, cyclical breast tenderness, and menstrual cycle regularity. GLA's conversion to PGE1 rather than to pro inflammatory arachidonic acid metabolites supports a more balanced prostaglandin profile during the luteal phase the period most associated with premenstrual symptoms.

Cold pressing uses mechanical pressure at controlled low temperatures, preserving the full fatty acid profile including heat sensitive GLA and linoleic acid. Solvent extraction using hexane at elevated temperatures degrades polyunsaturated fatty acids, destroys native tocopherols (Vitamin E), and may leave trace solvent residues in the finished oil. Cold pressed EPO retains its complete fatty acid composition, natural antioxidant content, and guaranteed GLA potency.

Do not use if you have a seizure disorder or are taking phenothiazine medications GLA may lower the seizure threshold in susceptible individuals when combined with phenothiazines. Consult a healthcare practitioner before use if you are pregnant or breastfeeding. Consult a healthcare practitioner before use if you are taking blood-thinning medications such as warfarin GLA's conversion to PGE1 has anti-aggregatory properties that may interact with anticoagulant therapy.