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GABA 750 mg gamma aminobutyric acid supplement capsules
GABA 750 mg high potency supplement Canada
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GABA 750 mg gamma aminobutyric acid supplement capsules

GABA 750mg Per Capsule High-Potency Fermentation Derived Gamma-Aminobutyric Acid

Each capsule delivers 750mg of gamma-aminobutyric acid (GABA), produced by microbial fermentation chemically identical to endogenous GABA. At the recommended dose of 1–4 capsules per day, this formula provides 750mg–3,000mg of GABA daily.

What Is GABA

Gamma-aminobutyric acid (GABA) is the primary inhibitory neurotransmitter in the central nervous system. It is synthesized in the brain from glutamate via the enzyme glutamate decarboxylase and acts by binding to GABA-A and GABA-B receptors on neurons, reducing neuronal excitability. GABA plays a central role in regulating the balance between excitatory and inhibitory signalling a balance that underlies cognitive function, stress response, muscle tone, and nervous system tone.

Fermentation-Derived GABA

The GABA in this formula is produced by microbial fermentation the same biosynthetic process used to produce pharmaceutical-grade amino acids and vitamins. Fermentation-derived GABA is chemically identical to the GABA produced endogenously in the brain. It is not derived from animal sources and is suitable for vegans and vegetarians.

Who This Is For

Adults seeking a high-potency, fermentation-derived GABA supplement. Suitable for vegans and vegetarians. Consult a healthcare practitioner before use if you are pregnant or breastfeeding, have a medical condition, or are taking medications.

GABA 750mg | Gamma Aminobutyric Acid | Fermentation Derived | 90 Vcaps

$24.99

Health Canada Licensed Natural Health Product (NPN 80139642)

Shipping calculated at checkout.

GABA 750mg Per Capsule High-Potency Fermentation Derived Gamma-Aminobutyric Acid

Each capsule delivers 750mg of gamma-aminobutyric acid (GABA), produced by microbial fermentation chemically identical to endogenous GABA. At the recommended dose of 1–4 capsules per day, this formula provides 750mg–3,000mg of GABA daily.

What Is GABA

Gamma-aminobutyric acid (GABA) is the primary inhibitory neurotransmitter in the central nervous system. It is synthesized in the brain from glutamate via the enzyme glutamate decarboxylase and acts by binding to GABA-A and GABA-B receptors on neurons, reducing neuronal excitability. GABA plays a central role in regulating the balance between excitatory and inhibitory signalling a balance that underlies cognitive function, stress response, muscle tone, and nervous system tone.

Fermentation-Derived GABA

The GABA in this formula is produced by microbial fermentation the same biosynthetic process used to produce pharmaceutical-grade amino acids and vitamins. Fermentation-derived GABA is chemically identical to the GABA produced endogenously in the brain. It is not derived from animal sources and is suitable for vegans and vegetarians.

Who This Is For

Adults seeking a high-potency, fermentation-derived GABA supplement. Suitable for vegans and vegetarians. Consult a healthcare practitioner before use if you are pregnant or breastfeeding, have a medical condition, or are taking medications.

Supplement Facts

Supplement Facts

Serving Size: 1 Capsule

Servings Per Container: 120

Ingredient
Amount Per
Serving
% Daily
Value
GABA (Gamma-Aminobutyric Acid, Fermentation Derived)
750 mg
†

† Daily Value not established.

Other Ingredients:
Hypromellose (Vegetable Capsule Shell), Microcrystalline Cellulose, Magnesium Stearate. Vegan. Non-GMO. Gluten Free. Soy Free. Dairy Free. Egg Free. Peanut Free. Shellfish Free.

Clinical Research

Oral intake of aminobutyric acid affects mood and activities of central nervous system during stressed condition induced by mental tasks

Amino Acids, 2012 Randomized controlled trial

A randomized controlled trial evaluating the effect of oral GABA supplementation on mood and central nervous system activity during mentally stressful tasks. GABA supplementation produced significant reductions in markers of psychological stress and fatigue compared to placebo, and electroencephalographic (EEG) analysis showed changes in brain wave activity consistent with a relaxation response. Supports the use of oral GABA supplementation for stress and cognitive performance under demanding conditions.

GABA intake improves salivary IgA secretion during stress

Journal of Nutritional Science and Vitaminology, 2009 Randomized controlled trial

A randomized controlled trial examining the effect of oral GABA supplementation on salivary immunoglobulin A (IgA) secretion — a marker of mucosal immune function — during psychological stress. GABA supplementation significantly attenuated the stress-induced decline in salivary IgA compared to placebo, suggesting that oral GABA may support immune function during periods of psychological stress through its modulatory effects on the stress response.

Is GABA involved in anxiety? Investigations in the social interaction test

Neuropharmacology, 1982 Foundational pharmacology study

A foundational study examining the relationship between GABAergic signalling and anxiety-related behaviour, providing mechanistic context for the role of the GABA system in stress and anxiety responses. This study is part of the foundational literature establishing GABA receptor modulation as a target for anxiolytic interventions and provides the pharmacological rationale for GABA supplementation research in the context of stress and nervous system support.

Research information is provided for educational purposes and does not replace the product's approved label information.

Frequently Asked Questions

What is GABA and what does it do in the brain?

Gamma-aminobutyric acid (GABA) is the primary inhibitory neurotransmitter in the central nervous system. It is synthesized in the brain from glutamate via the enzyme glutamate decarboxylase and acts by binding to GABA-A and GABA-B receptors on neurons, reducing neuronal excitability. GABA plays a central role in regulating the balance between excitatory and inhibitory signalling a balance that underlies cognitive function, stress response, muscle tone, and nervous system tone.

What does fermentation derived mean?

The GABA in this formula is produced by microbial fermentation the same biosynthetic process used to produce pharmaceutical-grade amino acids and vitamins. In fermentation, microorganisms convert a substrate (typically glucose or glutamate) into GABA via enzymatic activity. The resulting GABA is chemically identical to the GABA produced endogenously in the brain. It is not derived from animal sources and is suitable for vegans and vegetarians.

Can GABA supplements cross the blood brain barrier?

This is an active area of scientific discussion. GABA is a large, polar molecule, and the classical view held that it could not cross the blood-brain barrier (BBB) in meaningful amounts. More recent research has proposed that orally administered GABA may influence the nervous system through peripheral mechanisms including effects on the enteric nervous system and the gut brain axis and that some transport across the BBB may occur under certain conditions. The clinical evidence for orally supplemented GABA's effects continues to be evaluated.

Why should GABA not be taken with alcohol?

Both GABA and alcohol act on the GABAergic system alcohol enhances GABA-A receptor activity, producing inhibitory effects on the central nervous system. Combining GABA supplementation with alcohol may produce additive CNS depressant effects. Avoid use with alcohol as directed on the Health Canada licensed label (NPN 80139642).

Canadian-Made

Lab-Tested

Health Canada Approved

20 Years of Research

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