Black Maca and L-Arginine | Performance and Circulation | 90 Capsules | NPN 80144129
Each capsule delivers two complementary active ingredients: 200mg of black maca root extract (Lepidium meyenii, 4:1, QCE 800mg) and 400mg of L-Arginine (as L-Arginine monohydrochloride). L-Arginine is the primary dietary precursor to nitric oxide, the signaling molecule that causes vasodilation by relaxing vascular smooth muscle, supporting healthy circulation and cardiovascular function. Black maca contributes the adaptogenic and energy supporting properties of Lepidium meyenii. Together these two ingredients address circulation and physical performance from complementary directions: L-Arginine through the nitric oxide pathway and black maca through its unique macamide bioactives. Helps support cardiovascular health. Helps support healthy circulation. Health Canada approved (NPN 80144129). Made in Canada in a GMP certified facility. 90 capsules.
Key Features
• Helps support cardiovascular health
• Helps support healthy circulation
• 400mg L-Arginine (as L-Arginine monohydrochloride) per capsule
• 200mg black maca root extract per capsule (4:1, QCE 800mg)
• L-Arginine: the primary dietary precursor to nitric oxide
• Nitric oxide supports vasodilation and healthy blood flow
• Black maca: the rarest maca variety, studied for energy and vitality
• Complementary dual ingredient formula: nitric oxide pathway plus maca bioactives
• At the suggested dose: 1,600mg L-Arginine and QCE 3,200mg black maca per day
• Vegan capsule (hypromellose)
• Health Canada approved (NPN 80144129)
• Made in Canada in a GMP certified facility
L-Arginine: The Nitric Oxide Precursor
L-Arginine is a conditionally essential amino acid and the primary substrate for nitric oxide synthase (NOS), the enzyme responsible for producing nitric oxide (NO) in the body. The L-Arginine to nitric oxide pathway is one of the most important signaling mechanisms in cardiovascular physiology.
The Nitric Oxide Pathway: Nitric oxide synthase enzymes (endothelial NOS, neuronal NOS, and inducible NOS) convert L-Arginine to L-Citrulline, releasing nitric oxide as a byproduct. Nitric oxide then diffuses into adjacent vascular smooth muscle cells, where it activates soluble guanylate cyclase, increasing cyclic GMP (cGMP) levels. Elevated cGMP activates protein kinase G, which phosphorylates myosin light chain kinase and reduces its activity, causing smooth muscle relaxation and vasodilation. This vasodilation increases the diameter of blood vessels, reducing vascular resistance and supporting healthy blood flow and circulation.
Endothelial Function: The endothelium, the single cell layer lining the interior of blood vessels, is the primary site of nitric oxide production in the cardiovascular system. Endothelial NOS (eNOS) continuously produces small amounts of nitric oxide that maintain vascular tone and support healthy endothelial function. L-Arginine availability is a key factor in eNOS activity, and supplemental L-Arginine supports the substrate availability for this pathway.
L-Arginine Monohydrochloride: This formula uses L-Arginine as the monohydrochloride salt rather than free base L-Arginine. The monohydrochloride form is more stable, has better solubility, and is the form used in pharmaceutical grade L-Arginine preparations. It provides the same L-Arginine amino acid as the free base form but with improved stability and consistency.
Black Maca: Complementary Adaptogenic Support
The black maca component of this formula provides 200mg of 4:1 concentrated root extract per capsule, equivalent to 800mg of raw black maca root (QCE 800mg per capsule, QCE 3,200mg per day at the suggested dose). Black maca (Lepidium meyenii) is the rarest of the three maca colour varieties, comprising approximately 15% of the Peruvian maca harvest, and has been specifically studied for its energy and vitality supporting properties.
Macamides and Macaenes: The primary bioactive compounds in black maca are macamides and macaenes, benzylated fatty acids and their amides that are unique to Lepidium meyenii and are not found in any other plant. These compounds are the primary marker compounds for maca quality and are associated with maca's energy and vitality properties. The 4:1 concentration ratio means that 4 grams of raw black maca root were used to produce each gram of extract, concentrating the macamides and other bioactives relative to raw maca powder.
Complementary Mechanisms: L-Arginine and black maca address performance and vitality through distinct and complementary mechanisms. L-Arginine works through the nitric oxide pathway to support vasodilation and healthy circulation. Black maca contributes its unique macamide bioactives associated with energy and vitality. Together they form a dual ingredient formula that addresses both the circulatory and the adaptogenic dimensions of physical performance support.
Understanding the QCE: Maca Extract Potency
The maca component of this formula is a 4:1 concentrated extract with a QCE (Quantity of Crude Equivalent) of 800mg per capsule. QCE is the Health Canada standardized notation for expressing the raw material equivalent of a concentrated herbal extract. A 4:1 extract means that 4 grams of raw black maca root were used to produce 1 gram of extract. Each 200mg capsule therefore contains the concentrated bioactive compounds from 800mg of raw black maca root. At the suggested dose of 4 capsules per day, the daily maca dose is 800mg of 4:1 extract, equivalent to 3,200mg (QCE 3,200mg) of raw black maca root.
Understanding the Dosage
Per capsule: Black maca root extract (4:1, QCE 800mg): 200mg; L-Arginine (as L-Arginine monohydrochloride): 400mg
Suggested Use: Adults: 2 capsules, 2 times per day (4 capsules per day)
Daily totals at suggested dose: 800mg black maca extract (QCE 3,200mg); 1,600mg L-Arginine
Total Capsules: 90 (approximately 22 days supply at the suggested dose)
Non Medicinal Ingredients: Hypromellose, Magnesium Stearate, Microcrystalline Cellulose
Consult your healthcare provider to determine the appropriate dosage and duration of use for your individual needs.
Who May Consider This Product
• Adults seeking support for cardiovascular health and healthy circulation
• Those wanting a nitric oxide precursor (L-Arginine) combined with black maca in a single formula
• Individuals interested in the complementary mechanisms of L-Arginine and maca for performance support
• Those wanting a Health Canada approved, Canadian made combination formula
• Vegans and vegetarians (hypromellose capsule)
Quality and Purity
• Health Canada approved (NPN 80144129)
• 400mg L-Arginine (monohydrochloride) per capsule
• 200mg black maca root extract (4:1, QCE 800mg) per capsule
• Vegan hypromellose capsule
• 90 capsules (approximately 22 days supply at suggested dose)
• Made in Canada in a GMP certified facility
Storage
Store in a cool, dry place away from direct sunlight. Keep bottle tightly sealed after each use.
Safety Information and Cautions
Consult a healthcare professional before use if you are taking blood pressure medications, as L-Arginine's vasodilatory effects may potentiate antihypertensive medications. Consult a healthcare professional before use if you have kidney or liver conditions, as L-Arginine is metabolized in the liver and kidneys. Consult a healthcare professional before use if you are pregnant or breastfeeding. Consult a healthcare professional before use if you have any medical condition or are taking medications. Discontinue use 2 weeks prior to any scheduled surgery. Maca belongs to the Brassicaceae family and contains glucosinolates; individuals with thyroid conditions should consult a healthcare provider before use. This product is not intended to diagnose, treat, cure, or prevent any disease.
Keep out of reach of children.
This product is approved by Health Canada (NPN 80144129).
About Black Maca and L-Arginine | Performance and Circulation | NPN 80144129
This dual ingredient formula combines 400mg of L-Arginine (as L-Arginine monohydrochloride) and 200mg of black maca root extract (Lepidium meyenii, 4:1, QCE 800mg) per capsule to support cardiovascular health and healthy circulation from complementary directions. L-Arginine is the primary dietary precursor to nitric oxide, the signaling molecule that causes vasodilation by relaxing vascular smooth muscle and supporting healthy blood flow. Black maca contributes the unique macamide bioactives of Lepidium meyenii associated with energy and vitality. At the suggested dose of 4 capsules per day, this formula delivers 1,600mg of L-Arginine and the equivalent of 3,200mg of raw black maca root daily. Health Canada approved (NPN 80144129) for helping support cardiovascular health and healthy circulation. Made in Canada in a GMP certified facility. 90 capsules.
Black Maca and L-Arginine | Performance and Circulation | 90 Capsules | NPN 80144129
Each capsule delivers two complementary active ingredients: 200mg of black maca root extract (Lepidium meyenii, 4:1, QCE 800mg) and 400mg of L-Arginine (as L-Arginine monohydrochloride). L-Arginine is the primary dietary precursor to nitric oxide, the signaling molecule that causes vasodilation by relaxing vascular smooth muscle, supporting healthy circulation and cardiovascular function. Black maca contributes the adaptogenic and energy supporting properties of Lepidium meyenii. Together these two ingredients address circulation and physical performance from complementary directions: L-Arginine through the nitric oxide pathway and black maca through its unique macamide bioactives. Helps support cardiovascular health. Helps support healthy circulation. Health Canada approved (NPN 80144129). Made in Canada in a GMP certified facility. 90 capsules.
Key Features
• Helps support cardiovascular health
• Helps support healthy circulation
• 400mg L-Arginine (as L-Arginine monohydrochloride) per capsule
• 200mg black maca root extract per capsule (4:1, QCE 800mg)
• L-Arginine: the primary dietary precursor to nitric oxide
• Nitric oxide supports vasodilation and healthy blood flow
• Black maca: the rarest maca variety, studied for energy and vitality
• Complementary dual ingredient formula: nitric oxide pathway plus maca bioactives
• At the suggested dose: 1,600mg L-Arginine and QCE 3,200mg black maca per day
• Vegan capsule (hypromellose)
• Health Canada approved (NPN 80144129)
• Made in Canada in a GMP certified facility
L-Arginine: The Nitric Oxide Precursor
L-Arginine is a conditionally essential amino acid and the primary substrate for nitric oxide synthase (NOS), the enzyme responsible for producing nitric oxide (NO) in the body. The L-Arginine to nitric oxide pathway is one of the most important signaling mechanisms in cardiovascular physiology.
The Nitric Oxide Pathway: Nitric oxide synthase enzymes (endothelial NOS, neuronal NOS, and inducible NOS) convert L-Arginine to L-Citrulline, releasing nitric oxide as a byproduct. Nitric oxide then diffuses into adjacent vascular smooth muscle cells, where it activates soluble guanylate cyclase, increasing cyclic GMP (cGMP) levels. Elevated cGMP activates protein kinase G, which phosphorylates myosin light chain kinase and reduces its activity, causing smooth muscle relaxation and vasodilation. This vasodilation increases the diameter of blood vessels, reducing vascular resistance and supporting healthy blood flow and circulation.
Endothelial Function: The endothelium, the single cell layer lining the interior of blood vessels, is the primary site of nitric oxide production in the cardiovascular system. Endothelial NOS (eNOS) continuously produces small amounts of nitric oxide that maintain vascular tone and support healthy endothelial function. L-Arginine availability is a key factor in eNOS activity, and supplemental L-Arginine supports the substrate availability for this pathway.
L-Arginine Monohydrochloride: This formula uses L-Arginine as the monohydrochloride salt rather than free base L-Arginine. The monohydrochloride form is more stable, has better solubility, and is the form used in pharmaceutical grade L-Arginine preparations. It provides the same L-Arginine amino acid as the free base form but with improved stability and consistency.
Black Maca: Complementary Adaptogenic Support
The black maca component of this formula provides 200mg of 4:1 concentrated root extract per capsule, equivalent to 800mg of raw black maca root (QCE 800mg per capsule, QCE 3,200mg per day at the suggested dose). Black maca (Lepidium meyenii) is the rarest of the three maca colour varieties, comprising approximately 15% of the Peruvian maca harvest, and has been specifically studied for its energy and vitality supporting properties.
Macamides and Macaenes: The primary bioactive compounds in black maca are macamides and macaenes, benzylated fatty acids and their amides that are unique to Lepidium meyenii and are not found in any other plant. These compounds are the primary marker compounds for maca quality and are associated with maca's energy and vitality properties. The 4:1 concentration ratio means that 4 grams of raw black maca root were used to produce each gram of extract, concentrating the macamides and other bioactives relative to raw maca powder.
Complementary Mechanisms: L-Arginine and black maca address performance and vitality through distinct and complementary mechanisms. L-Arginine works through the nitric oxide pathway to support vasodilation and healthy circulation. Black maca contributes its unique macamide bioactives associated with energy and vitality. Together they form a dual ingredient formula that addresses both the circulatory and the adaptogenic dimensions of physical performance support.
Understanding the QCE: Maca Extract Potency
The maca component of this formula is a 4:1 concentrated extract with a QCE (Quantity of Crude Equivalent) of 800mg per capsule. QCE is the Health Canada standardized notation for expressing the raw material equivalent of a concentrated herbal extract. A 4:1 extract means that 4 grams of raw black maca root were used to produce 1 gram of extract. Each 200mg capsule therefore contains the concentrated bioactive compounds from 800mg of raw black maca root. At the suggested dose of 4 capsules per day, the daily maca dose is 800mg of 4:1 extract, equivalent to 3,200mg (QCE 3,200mg) of raw black maca root.
Understanding the Dosage
Per capsule: Black maca root extract (4:1, QCE 800mg): 200mg; L-Arginine (as L-Arginine monohydrochloride): 400mg
Suggested Use: Adults: 2 capsules, 2 times per day (4 capsules per day)
Daily totals at suggested dose: 800mg black maca extract (QCE 3,200mg); 1,600mg L-Arginine
Total Capsules: 90 (approximately 22 days supply at the suggested dose)
Non Medicinal Ingredients: Hypromellose, Magnesium Stearate, Microcrystalline Cellulose
Consult your healthcare provider to determine the appropriate dosage and duration of use for your individual needs.
Who May Consider This Product
• Adults seeking support for cardiovascular health and healthy circulation
• Those wanting a nitric oxide precursor (L-Arginine) combined with black maca in a single formula
• Individuals interested in the complementary mechanisms of L-Arginine and maca for performance support
• Those wanting a Health Canada approved, Canadian made combination formula
• Vegans and vegetarians (hypromellose capsule)
Quality and Purity
• Health Canada approved (NPN 80144129)
• 400mg L-Arginine (monohydrochloride) per capsule
• 200mg black maca root extract (4:1, QCE 800mg) per capsule
• Vegan hypromellose capsule
• 90 capsules (approximately 22 days supply at suggested dose)
• Made in Canada in a GMP certified facility
Storage
Store in a cool, dry place away from direct sunlight. Keep bottle tightly sealed after each use.
Safety Information and Cautions
Consult a healthcare professional before use if you are taking blood pressure medications, as L-Arginine's vasodilatory effects may potentiate antihypertensive medications. Consult a healthcare professional before use if you have kidney or liver conditions, as L-Arginine is metabolized in the liver and kidneys. Consult a healthcare professional before use if you are pregnant or breastfeeding. Consult a healthcare professional before use if you have any medical condition or are taking medications. Discontinue use 2 weeks prior to any scheduled surgery. Maca belongs to the Brassicaceae family and contains glucosinolates; individuals with thyroid conditions should consult a healthcare provider before use. This product is not intended to diagnose, treat, cure, or prevent any disease.
Keep out of reach of children.
This product is approved by Health Canada (NPN 80144129).
About Black Maca and L-Arginine | Performance and Circulation | NPN 80144129
This dual ingredient formula combines 400mg of L-Arginine (as L-Arginine monohydrochloride) and 200mg of black maca root extract (Lepidium meyenii, 4:1, QCE 800mg) per capsule to support cardiovascular health and healthy circulation from complementary directions. L-Arginine is the primary dietary precursor to nitric oxide, the signaling molecule that causes vasodilation by relaxing vascular smooth muscle and supporting healthy blood flow. Black maca contributes the unique macamide bioactives of Lepidium meyenii associated with energy and vitality. At the suggested dose of 4 capsules per day, this formula delivers 1,600mg of L-Arginine and the equivalent of 3,200mg of raw black maca root daily. Health Canada approved (NPN 80144129) for helping support cardiovascular health and healthy circulation. Made in Canada in a GMP certified facility. 90 capsules.
Canadian-Made
Lab-Tested
Health Canada Approved
