Chromium Picolinate 500mcg Elemental Chromium | Glucose Metabolism Support | 150 Vegan Capsules
Each vegan capsule delivers 500mcg of elemental chromium from 4030mcg of chromium picolinate. Supports healthy glucose metabolism by potentiating insulin signalling at the cellular level via chromodulin.
Health Canada licensed NPN 80036350. Made in Canada. 150 vegan capsules, up to a 5 month supply at 1 capsule per day.
Source
Chromium source: Trivalent chromium (Cr3+), the biologically active form of chromium found naturally in whole grains, broccoli, green beans, meat, and brewer's yeast.
Picolinic acid source: A naturally occurring organic acid produced in the human body as a metabolite of tryptophan via the kynurenine pathway. Chelating chromium with picolinic acid dramatically improves intestinal absorption compared to inorganic chromium chloride, which has bioavailability estimated at less than 1%.
What Is Chromium Picolinate?
Chromium picolinate is trivalent chromium (Cr3+) chelated with picolinic acid. The chelation significantly increases chromium absorption through the intestinal wall. It is the most extensively researched form of supplemental chromium, with the largest body of peer-reviewed clinical evidence supporting its role in glucose metabolism and insulin sensitivity.
What Does Chromium Picolinate Do?
Chromium is a component of chromodulin, an oligopeptide that binds to the insulin receptor and amplifies its signalling activity, enhancing GLUT4 glucose transporter translocation and cellular glucose uptake. Without adequate chromium, insulin signalling is less efficient and the body requires more insulin to clear glucose from the bloodstream.
Key Benefits
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Supports healthy glucose metabolism Potentiates insulin signalling via chromodulin, helping maintain blood glucose within normal ranges
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Supports insulin sensitivity Amplifies the insulin receptor signal, improving cellular glucose uptake efficiency
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Helps maintain healthy carbohydrate and lipid metabolism Associated with healthy triglyceride and HDL cholesterol levels within normal ranges
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Chromium picolinate form Superior bioavailability versus inorganic chromium chloride (less than 1% absorption)
- Source: Cr3+ from mineral chromium, chelated with picolinic acid (tryptophan metabolite)
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500mcg elemental chromium per capsule From 4030mcg chromium picolinate | Single ingredient
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Health Canada licensed NPN 80036350 | GMP certified | Made in Canada
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150 vegan capsules Up to a 5 month supply at 1 capsule per day
How It Works
Chromodulin and Insulin Amplification
Chromium activates chromodulin, which binds to the insulin receptor and amplifies its tyrosine kinase activity. This enhances GLUT4 translocation to cell membranes, increasing cellular glucose uptake. Without adequate chromium, this amplification step is impaired and insulin efficiency declines.
Why Picolinate Form Absorbs Better
Inorganic chromium chloride has bioavailability below 1%. Picolinic acid chelation facilitates chromium transport across the intestinal epithelium, significantly increasing absorption and tissue delivery. This is why chromium picolinate is the form used in the majority of human clinical trials.
Postprandial Glucose and Lipid Support
By enhancing insulin signalling, chromium picolinate supports efficient postprandial glucose clearance and healthy fasting blood glucose. Because insulin resistance is closely linked to dyslipidemia, improved insulin sensitivity is also associated with healthy triglyceride and HDL cholesterol levels within normal ranges.
Who May Have Suboptimal Chromium Status
Diets high in refined carbohydrates and processed foods are low in chromium and increase urinary chromium excretion. Physical stress, intense exercise, pregnancy, and aging also increase chromium requirements or reduce absorption efficiency.
Medicinal Ingredient (per capsule)
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Chromium Picolinate 4030mcg providing Elemental Chromium 500mcg | Source: trivalent Cr3+ chelated with picolinic acid (tryptophan metabolite) | NPN 80036350
Non-medicinal ingredients: Vegetable capsule (hypromellose), microcrystalline cellulose, magnesium stearate (vegetable source). No artificial colours, flavours, sweeteners, or preservatives. Vegan. Gluten free. Non-GMO.
Quality and Trust
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NPN 80036350 Licensed by Health Canada as a Natural Health Product
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Made in Canada GMP certified facility under Health Canada oversight
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Independently tested Purity and potency verified by a third-party laboratory
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Source: Cr3+ chelated with picolinic acid Most bioavailable and most clinically researched supplemental chromium form
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Vegan capsule Hypromellose shell, no gelatin or animal derived ingredients
- Non-GMO and gluten free
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150 vegan capsules Up to a 5 month supply at 1 capsule per day
Who This Is For
- Consult a healthcare practitioner before use if you have diabetes or impaired glucose tolerance and are taking antidiabetic medications, have kidney or liver disease, are pregnant or breastfeeding, or are taking antacids, corticosteroids, or NSAIDs
- Adults seeking glucose metabolism and blood sugar balance support from the most bioavailable form of chromium
- Those supporting healthy insulin sensitivity and efficient postprandial carbohydrate metabolism
- Individuals with dietary gaps in chromium due to refined food diets, high physical stress, or increased physiological demand
How to Use
Adults: Take 1 capsule daily with a meal containing carbohydrates, or as directed by a healthcare practitioner. Do not exceed the recommended daily dose.
Safety and Cautions
Consult a healthcare practitioner before use if you have diabetes or impaired glucose tolerance and are taking antidiabetic medications (including insulin or metformin), have kidney or liver disease, are pregnant or breastfeeding, or are taking antacids, corticosteroids, or NSAIDs. Store in a cool, dry place. Do not use if the seal is broken or missing. Keep out of reach of children.
NPN 80036350. This product is not intended to diagnose, treat, cure, or prevent any disease. All health claims are consistent with Health Canada's Natural Health Products Regulations.
