Acetyl L-Carnitine 637.5mg | Source of Carnitine | Energy Metabolism and Cognitive Function | 120 Vegan Capsules

Each vegan capsule delivers 637.5mg of Acetyl L-Carnitine (ALCAR) from 750mg of Acetyl L-Carnitine HCl. ALCAR crosses the blood-brain barrier efficiently and provides an acetyl group for acetylcholine synthesis in the brain. At the recommended dose of 3 capsules per day, this formula delivers 1912.5mg of ALCAR daily.

Health Canada licensed NPN 80141963. Made in Canada. 120 vegan capsules, 40 day supply at 3 capsules per day.

Source

ALCAR source: Acetyl L-Carnitine hydrochloride (HCl), a synthetically produced amino acid derivative. ALCAR is not derived from animal sources and is suitable for vegans and vegetarians. The HCl salt form is used for stability and precise dosing. Each 750mg of ALCAR HCl provides 637.5mg of free-base Acetyl L-Carnitine (85% free-base equivalent), which is the medicinal ingredient amount stated per capsule in accordance with Health Canada NHP labelling requirements.

What Is Acetyl L-Carnitine?

Acetyl L-Carnitine (ALCAR) is the acetylated form of L-carnitine, an amino acid derivative synthesized in the body from lysine and methionine. The acetyl group distinguishes ALCAR from standard L-carnitine in two critical ways: it allows ALCAR to cross the blood-brain barrier efficiently, and it provides an acetyl group that can be donated to choline to form acetylcholine, the primary neurotransmitter of the cholinergic system. Standard L-carnitine does not cross the blood-brain barrier efficiently and cannot contribute to acetylcholine synthesis.

How Is ALCAR Different from Standard L-Carnitine?

Standard L-carnitine supports peripheral energy metabolism by transporting fatty acids into mitochondria for ATP production. ALCAR does this too, but additionally crosses the blood-brain barrier and donates its acetyl group for acetylcholine synthesis in the brain. This makes ALCAR the preferred carnitine form for cognitive function support, while standard L-carnitine is more commonly used for peripheral energy and exercise performance.

Key Benefits

Source of carnitine Health Canada licensed claim under NPN 80141963
Supports energy metabolism Health Canada licensed claim | Carnitine transports long-chain fatty acids across the inner mitochondrial membrane for beta-oxidation and ATP production
Supports cognitive function Health Canada licensed claim | ALCAR crosses the blood-brain barrier and donates its acetyl group for acetylcholine synthesis via choline acetyltransferase (ChAT)
637.5mg ALCAR per capsule From 750mg Acetyl L-Carnitine HCl | 1912.5mg ALCAR per daily dose of 3 capsules
Source: synthetically produced ALCAR HCl Not derived from animal sources | Suitable for vegans and vegetarians
Vegan capsule Hypromellose shell, no gelatin or animal derived ingredients
Health Canada licensed NPN 80141963 | GMP certified | Made in Canada
120 vegan capsules 40 day supply at 3 capsules per day

How It Works

Carnitine and Mitochondrial Fatty Acid Transport

Long-chain fatty acids (14 carbons or longer) cannot cross the inner mitochondrial membrane without carnitine. They are first activated to acyl-CoA, then transferred to carnitine by carnitine palmitoyltransferase I (CPT-I), forming acylcarnitine. The acylcarnitine crosses the inner mitochondrial membrane, where the fatty acid is transferred back to CoA for beta-oxidation. Beta-oxidation progressively cleaves two-carbon units, generating acetyl-CoA, NADH, and FADH2 for ATP production via the Krebs cycle and electron transport chain. This pathway is the primary energy source for the heart and a major energy source for skeletal muscle during sustained activity.

ALCAR and the Blood-Brain Barrier

The blood-brain barrier is a selective barrier that restricts what substances can enter the brain from the bloodstream. Standard L-carnitine does not cross it efficiently. ALCAR's acetyl group increases its lipophilicity and allows it to utilize specific transport mechanisms, enabling efficient entry into the central nervous system. Once inside the brain, ALCAR supports mitochondrial function in neurons and contributes its acetyl group for acetylcholine synthesis.

Acetylcholine Synthesis and Cognitive Function

Inside the brain, ALCAR donates its acetyl group to choline via choline acetyltransferase (ChAT) to form acetylcholine, the primary neurotransmitter of the cholinergic system. Acetylcholine is essential for attention, learning, memory formation, and memory retrieval. Neurons also have exceptionally high energy demands. ALCAR supports neuronal mitochondrial function by facilitating fatty acid transport and contributing to mitochondrial acetyl-CoA pools, supporting the energy supply for neuronal activity.

Why ALCAR HCl and Not Free-Base ALCAR

The HCl salt form is more stable and hygroscopically stable than free-base ALCAR, making it the preferred form for capsule manufacturing. Each 750mg of ALCAR HCl provides 637.5mg of free-base Acetyl L-Carnitine (85% free-base equivalent), which is the biologically active amount and the figure stated as the medicinal ingredient per capsule in accordance with Health Canada NHP labelling requirements.

Medicinal Ingredient (per capsule)

Acetyl L-Carnitine 637.5mg From 750mg Acetyl L-Carnitine HCl | Source: synthetically produced ALCAR HCl | Source of carnitine | Supports energy metabolism and cognitive function | NPN 80141963

Non-medicinal ingredients: Hypromellose (vegetable capsule shell), microcrystalline cellulose, magnesium stearate (vegetable source). No artificial colours, flavours, sweeteners, or preservatives. Vegan. Gluten free. Non-GMO.

Per Daily Dose (3 Capsules)

Acetyl L-Carnitine: 1912.5mg (from 2250mg Acetyl L-Carnitine HCl)

Quality and Trust

NPN 80141963 Licensed by Health Canada as a Natural Health Product
Made in Canada GMP certified facility under Health Canada oversight
637.5mg ALCAR per capsule From 750mg Acetyl L-Carnitine HCl
Source: synthetically produced ALCAR HCl Vegan, not animal derived
Vegan capsule Hypromellose shell, no gelatin or animal derived ingredients
Non-GMO, gluten free, dairy free, soy free
120 vegan capsules 40 day supply at 3 capsules per day

Who This Is For

Ask a healthcare practitioner before use if you are pregnant or breastfeeding, have kidney disease, or have a seizure disorder
Adults seeking a source of carnitine that crosses the blood-brain barrier for cognitive function support alongside energy metabolism support
Those who want ALCAR specifically rather than standard L-carnitine, for its acetylcholine precursor activity and blood-brain barrier penetration
Vegans and vegetarians seeking a synthetically produced, non-animal-derived carnitine supplement

How to Use

Adults: Take 1 capsule, 3 times per day. Taking with food may help minimize gastrointestinal discomfort.

At 3 capsules per day, 120 capsules provides a 40 day supply.

Safety and Cautions

Ask a healthcare practitioner before use if you are pregnant or breastfeeding, have kidney disease, or have a seizure disorder. Gastrointestinal discomfort may occur; taking with food may help. Store in a cool, dry place away from direct sunlight and moisture. Do not use if the seal is broken or missing. Keep out of reach of children.

NPN 80141963. This product is not intended to diagnose, treat, cure, or prevent any disease. All health claims are consistent with Health Canada's Natural Health Products Regulations.

Ingredients

How to Use

FAQ

Q: What is Acetyl L-Carnitine and how is it different from regular L-Carnitine?
A: L-Carnitine is a naturally occurring amino acid derivative synthesized in the body from lysine and methionine, found in virtually all cells with the highest concentrations in tissues with high energy demands such as the heart, skeletal muscle, and brain. Acetyl L-Carnitine (ALCAR) is the acetylated form of L-carnitine, with an acetyl group (CH3CO-) attached to the carnitine molecule. This acetylation creates two critical differences from standard L-carnitine. First, ALCAR crosses the blood-brain barrier efficiently, while standard L-carnitine does not. Second, ALCAR can donate its acetyl group for acetylcholine synthesis in the brain. These two properties make ALCAR the preferred carnitine form for cognitive function support, while standard L-carnitine is more commonly used for peripheral energy metabolism.

Q: What are the Health Canada approved uses for this product?
A: This product is approved by Health Canada (NPN 80141963) for the following uses: source of carnitine; supports energy metabolism; and supports cognitive function. This product is not intended to diagnose, treat, cure, or prevent any disease.

Q: What does "637.5mg from 750mg ALCAR HCl" mean?
A: This formula uses Acetyl L-Carnitine hydrochloride (HCl), the salt form of ALCAR. The HCl salt is more stable than the free base form of ALCAR. Each 750mg of ALCAR HCl contains 637.5mg of free base Acetyl L-Carnitine, which is 85% of the HCl salt weight. The medicinal ingredient is stated as 637.5mg because this is the actual amount of active Acetyl L-Carnitine delivered per capsule, with the remaining weight being the hydrochloride component of the salt. This is standard practice in supplement labelling and ensures accurate representation of the actual ALCAR content.

Q: How does carnitine support energy metabolism?
A: Carnitine's primary biochemical role is to transport long-chain fatty acids across the inner mitochondrial membrane for beta-oxidation, the process by which fatty acids are broken down to generate ATP. Long-chain fatty acids cannot cross the inner mitochondrial membrane on their own. They must be transferred to carnitine by the enzyme carnitine palmitoyltransferase I (CPT-I), forming acylcarnitine, which is then transported across the membrane. Inside the mitochondrial matrix, the fatty acid is released from carnitine and undergoes beta-oxidation, generating acetyl-CoA, NADH, and FADH2 for ATP production via the Krebs cycle and electron transport chain. Without adequate carnitine, long-chain fatty acid transport into the mitochondria is impaired and fat cannot be efficiently used for energy.

Q: Why does ALCAR cross the blood-brain barrier when regular L-carnitine does not?
A: The blood-brain barrier is a selective barrier formed by specialized endothelial cells lining the brain's blood vessels that tightly controls what substances can enter the brain. Standard L-carnitine is a highly polar, water-soluble molecule that does not efficiently cross the blood-brain barrier. The acetyl group on ALCAR increases its lipophilicity (fat solubility) and allows it to utilize specific transport mechanisms that facilitate its entry into the brain. This is why ALCAR is the carnitine form used for cognitive function support, while standard L-carnitine primarily supports peripheral energy metabolism in muscle and other tissues.

Q: How does ALCAR support acetylcholine synthesis?
A: Once inside the brain, ALCAR can donate its acetyl group to choline via the enzyme choline acetyltransferase (ChAT) to form acetylcholine, the primary neurotransmitter of the cholinergic system. The cholinergic system is involved in attention, learning, memory formation, and memory retrieval. By providing an acetyl group for acetylcholine synthesis alongside its role as a source of carnitine for mitochondrial energy support in neurons, ALCAR supports cholinergic neurotransmission through two complementary mechanisms in a single molecule.

Q: What is the daily dose and how many days does one bottle last?
A: The suggested use is 1 capsule, 3 times per day, providing 1912.5mg of Acetyl L-Carnitine daily (3 x 637.5mg). At this full suggested dose, the 120-capsule bottle provides a 40-day supply. Consult your healthcare provider to determine the appropriate daily dose for your individual needs.

Q: Is this product suitable for vegans and vegetarians?
A: Yes, this Acetyl L-Carnitine supplement is 100% vegan and suitable for both vegans and vegetarians. Although L-carnitine is found naturally in animal foods (particularly red meat and dairy), the ALCAR used in this supplement is produced through chemical synthesis, not from animal sources. The capsule shell is made from hypromellose (vegetable cellulose), not gelatin. All non-medicinal ingredients (hypromellose, magnesium stearate, microcrystalline cellulose) are plant-derived or mineral-based. The product is also non-GMO and free from gluten, dairy, and soy.

Q: Are there any safety considerations I should know about?
A: Consult a healthcare practitioner prior to use if you are pregnant or breastfeeding, have kidney disease, or have a seizure disorder. Individuals with kidney disease should use caution as impaired kidneys may affect carnitine metabolism and excretion. Individuals with a seizure disorder should consult a healthcare provider before use, as there are case reports of ALCAR potentially lowering the seizure threshold in susceptible individuals. May cause gastrointestinal discomfort in some individuals; taking with food may help minimize this. Do not use if you have a known allergy to carnitine. This product is not intended to diagnose, treat, cure, or prevent any disease.

Q: Why is this product Health Canada approved?
A: This product holds NPN 80141963 from Health Canada, meaning it has been reviewed and approved for safety, efficacy, and quality as a natural health product. The NPN designation confirms that the approved uses (source of carnitine, supports energy metabolism, supports cognitive function) are backed by evidence reviewed by Health Canada, and that the product meets Canadian regulatory standards for ingredient quality, dosage, and labelling.

Acetyl L-Carnitine 637.5mg | Source of Carnitine | Energy Metabolism and Cognitive Function | 120 Vegan Capsules

$29.99

Unit price: per

Health Canada Licensed Natural Health Product (NPN 80141963)

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Acetyl L-Carnitine 637.5mg | Source of Carnitine | Energy Metabolism and Cognitive Function | 120 Vegan Capsules

Each vegan capsule delivers 637.5mg of Acetyl L-Carnitine (ALCAR) from 750mg of Acetyl L-Carnitine HCl. ALCAR crosses the blood-brain barrier efficiently and provides an acetyl group for acetylcholine synthesis in the brain. At the recommended dose of 3 capsules per day, this formula delivers 1912.5mg of ALCAR daily.

Health Canada licensed NPN 80141963. Made in Canada. 120 vegan capsules, 40 day supply at 3 capsules per day.

Source

ALCAR source: Acetyl L-Carnitine hydrochloride (HCl), a synthetically produced amino acid derivative. ALCAR is not derived from animal sources and is suitable for vegans and vegetarians. The HCl salt form is used for stability and precise dosing. Each 750mg of ALCAR HCl provides 637.5mg of free-base Acetyl L-Carnitine (85% free-base equivalent), which is the medicinal ingredient amount stated per capsule in accordance with Health Canada NHP labelling requirements.

What Is Acetyl L-Carnitine?

Acetyl L-Carnitine (ALCAR) is the acetylated form of L-carnitine, an amino acid derivative synthesized in the body from lysine and methionine. The acetyl group distinguishes ALCAR from standard L-carnitine in two critical ways: it allows ALCAR to cross the blood-brain barrier efficiently, and it provides an acetyl group that can be donated to choline to form acetylcholine, the primary neurotransmitter of the cholinergic system. Standard L-carnitine does not cross the blood-brain barrier efficiently and cannot contribute to acetylcholine synthesis.

How Is ALCAR Different from Standard L-Carnitine?

Standard L-carnitine supports peripheral energy metabolism by transporting fatty acids into mitochondria for ATP production. ALCAR does this too, but additionally crosses the blood-brain barrier and donates its acetyl group for acetylcholine synthesis in the brain. This makes ALCAR the preferred carnitine form for cognitive function support, while standard L-carnitine is more commonly used for peripheral energy and exercise performance.

Key Benefits

Source of carnitine Health Canada licensed claim under NPN 80141963
Supports energy metabolism Health Canada licensed claim | Carnitine transports long-chain fatty acids across the inner mitochondrial membrane for beta-oxidation and ATP production
Supports cognitive function Health Canada licensed claim | ALCAR crosses the blood-brain barrier and donates its acetyl group for acetylcholine synthesis via choline acetyltransferase (ChAT)
637.5mg ALCAR per capsule From 750mg Acetyl L-Carnitine HCl | 1912.5mg ALCAR per daily dose of 3 capsules
Source: synthetically produced ALCAR HCl Not derived from animal sources | Suitable for vegans and vegetarians
Vegan capsule Hypromellose shell, no gelatin or animal derived ingredients
Health Canada licensed NPN 80141963 | GMP certified | Made in Canada
120 vegan capsules 40 day supply at 3 capsules per day

How It Works

Carnitine and Mitochondrial Fatty Acid Transport

Long-chain fatty acids (14 carbons or longer) cannot cross the inner mitochondrial membrane without carnitine. They are first activated to acyl-CoA, then transferred to carnitine by carnitine palmitoyltransferase I (CPT-I), forming acylcarnitine. The acylcarnitine crosses the inner mitochondrial membrane, where the fatty acid is transferred back to CoA for beta-oxidation. Beta-oxidation progressively cleaves two-carbon units, generating acetyl-CoA, NADH, and FADH2 for ATP production via the Krebs cycle and electron transport chain. This pathway is the primary energy source for the heart and a major energy source for skeletal muscle during sustained activity.

ALCAR and the Blood-Brain Barrier

The blood-brain barrier is a selective barrier that restricts what substances can enter the brain from the bloodstream. Standard L-carnitine does not cross it efficiently. ALCAR's acetyl group increases its lipophilicity and allows it to utilize specific transport mechanisms, enabling efficient entry into the central nervous system. Once inside the brain, ALCAR supports mitochondrial function in neurons and contributes its acetyl group for acetylcholine synthesis.

Acetylcholine Synthesis and Cognitive Function

Inside the brain, ALCAR donates its acetyl group to choline via choline acetyltransferase (ChAT) to form acetylcholine, the primary neurotransmitter of the cholinergic system. Acetylcholine is essential for attention, learning, memory formation, and memory retrieval. Neurons also have exceptionally high energy demands. ALCAR supports neuronal mitochondrial function by facilitating fatty acid transport and contributing to mitochondrial acetyl-CoA pools, supporting the energy supply for neuronal activity.

Why ALCAR HCl and Not Free-Base ALCAR

The HCl salt form is more stable and hygroscopically stable than free-base ALCAR, making it the preferred form for capsule manufacturing. Each 750mg of ALCAR HCl provides 637.5mg of free-base Acetyl L-Carnitine (85% free-base equivalent), which is the biologically active amount and the figure stated as the medicinal ingredient per capsule in accordance with Health Canada NHP labelling requirements.

Medicinal Ingredient (per capsule)

Acetyl L-Carnitine 637.5mg From 750mg Acetyl L-Carnitine HCl | Source: synthetically produced ALCAR HCl | Source of carnitine | Supports energy metabolism and cognitive function | NPN 80141963

Non-medicinal ingredients: Hypromellose (vegetable capsule shell), microcrystalline cellulose, magnesium stearate (vegetable source). No artificial colours, flavours, sweeteners, or preservatives. Vegan. Gluten free. Non-GMO.

Per Daily Dose (3 Capsules)

Acetyl L-Carnitine: 1912.5mg (from 2250mg Acetyl L-Carnitine HCl)

Quality and Trust

NPN 80141963 Licensed by Health Canada as a Natural Health Product
Made in Canada GMP certified facility under Health Canada oversight
637.5mg ALCAR per capsule From 750mg Acetyl L-Carnitine HCl
Source: synthetically produced ALCAR HCl Vegan, not animal derived
Vegan capsule Hypromellose shell, no gelatin or animal derived ingredients
Non-GMO, gluten free, dairy free, soy free
120 vegan capsules 40 day supply at 3 capsules per day

Who This Is For

Ask a healthcare practitioner before use if you are pregnant or breastfeeding, have kidney disease, or have a seizure disorder
Adults seeking a source of carnitine that crosses the blood-brain barrier for cognitive function support alongside energy metabolism support
Those who want ALCAR specifically rather than standard L-carnitine, for its acetylcholine precursor activity and blood-brain barrier penetration
Vegans and vegetarians seeking a synthetically produced, non-animal-derived carnitine supplement

How to Use

Adults: Take 1 capsule, 3 times per day. Taking with food may help minimize gastrointestinal discomfort.

At 3 capsules per day, 120 capsules provides a 40 day supply.

Safety and Cautions

Ask a healthcare practitioner before use if you are pregnant or breastfeeding, have kidney disease, or have a seizure disorder. Gastrointestinal discomfort may occur; taking with food may help. Store in a cool, dry place away from direct sunlight and moisture. Do not use if the seal is broken or missing. Keep out of reach of children.

NPN 80141963. This product is not intended to diagnose, treat, cure, or prevent any disease. All health claims are consistent with Health Canada's Natural Health Products Regulations.

Ingredients

How to Use

FAQ

Q: What is Acetyl L-Carnitine and how is it different from regular L-Carnitine?
A: L-Carnitine is a naturally occurring amino acid derivative synthesized in the body from lysine and methionine, found in virtually all cells with the highest concentrations in tissues with high energy demands such as the heart, skeletal muscle, and brain. Acetyl L-Carnitine (ALCAR) is the acetylated form of L-carnitine, with an acetyl group (CH3CO-) attached to the carnitine molecule. This acetylation creates two critical differences from standard L-carnitine. First, ALCAR crosses the blood-brain barrier efficiently, while standard L-carnitine does not. Second, ALCAR can donate its acetyl group for acetylcholine synthesis in the brain. These two properties make ALCAR the preferred carnitine form for cognitive function support, while standard L-carnitine is more commonly used for peripheral energy metabolism.

Q: What are the Health Canada approved uses for this product?
A: This product is approved by Health Canada (NPN 80141963) for the following uses: source of carnitine; supports energy metabolism; and supports cognitive function. This product is not intended to diagnose, treat, cure, or prevent any disease.

Q: What does "637.5mg from 750mg ALCAR HCl" mean?
A: This formula uses Acetyl L-Carnitine hydrochloride (HCl), the salt form of ALCAR. The HCl salt is more stable than the free base form of ALCAR. Each 750mg of ALCAR HCl contains 637.5mg of free base Acetyl L-Carnitine, which is 85% of the HCl salt weight. The medicinal ingredient is stated as 637.5mg because this is the actual amount of active Acetyl L-Carnitine delivered per capsule, with the remaining weight being the hydrochloride component of the salt. This is standard practice in supplement labelling and ensures accurate representation of the actual ALCAR content.

Q: How does carnitine support energy metabolism?
A: Carnitine's primary biochemical role is to transport long-chain fatty acids across the inner mitochondrial membrane for beta-oxidation, the process by which fatty acids are broken down to generate ATP. Long-chain fatty acids cannot cross the inner mitochondrial membrane on their own. They must be transferred to carnitine by the enzyme carnitine palmitoyltransferase I (CPT-I), forming acylcarnitine, which is then transported across the membrane. Inside the mitochondrial matrix, the fatty acid is released from carnitine and undergoes beta-oxidation, generating acetyl-CoA, NADH, and FADH2 for ATP production via the Krebs cycle and electron transport chain. Without adequate carnitine, long-chain fatty acid transport into the mitochondria is impaired and fat cannot be efficiently used for energy.

Q: Why does ALCAR cross the blood-brain barrier when regular L-carnitine does not?
A: The blood-brain barrier is a selective barrier formed by specialized endothelial cells lining the brain's blood vessels that tightly controls what substances can enter the brain. Standard L-carnitine is a highly polar, water-soluble molecule that does not efficiently cross the blood-brain barrier. The acetyl group on ALCAR increases its lipophilicity (fat solubility) and allows it to utilize specific transport mechanisms that facilitate its entry into the brain. This is why ALCAR is the carnitine form used for cognitive function support, while standard L-carnitine primarily supports peripheral energy metabolism in muscle and other tissues.

Q: How does ALCAR support acetylcholine synthesis?
A: Once inside the brain, ALCAR can donate its acetyl group to choline via the enzyme choline acetyltransferase (ChAT) to form acetylcholine, the primary neurotransmitter of the cholinergic system. The cholinergic system is involved in attention, learning, memory formation, and memory retrieval. By providing an acetyl group for acetylcholine synthesis alongside its role as a source of carnitine for mitochondrial energy support in neurons, ALCAR supports cholinergic neurotransmission through two complementary mechanisms in a single molecule.

Q: What is the daily dose and how many days does one bottle last?
A: The suggested use is 1 capsule, 3 times per day, providing 1912.5mg of Acetyl L-Carnitine daily (3 x 637.5mg). At this full suggested dose, the 120-capsule bottle provides a 40-day supply. Consult your healthcare provider to determine the appropriate daily dose for your individual needs.

Q: Is this product suitable for vegans and vegetarians?
A: Yes, this Acetyl L-Carnitine supplement is 100% vegan and suitable for both vegans and vegetarians. Although L-carnitine is found naturally in animal foods (particularly red meat and dairy), the ALCAR used in this supplement is produced through chemical synthesis, not from animal sources. The capsule shell is made from hypromellose (vegetable cellulose), not gelatin. All non-medicinal ingredients (hypromellose, magnesium stearate, microcrystalline cellulose) are plant-derived or mineral-based. The product is also non-GMO and free from gluten, dairy, and soy.

Q: Are there any safety considerations I should know about?
A: Consult a healthcare practitioner prior to use if you are pregnant or breastfeeding, have kidney disease, or have a seizure disorder. Individuals with kidney disease should use caution as impaired kidneys may affect carnitine metabolism and excretion. Individuals with a seizure disorder should consult a healthcare provider before use, as there are case reports of ALCAR potentially lowering the seizure threshold in susceptible individuals. May cause gastrointestinal discomfort in some individuals; taking with food may help minimize this. Do not use if you have a known allergy to carnitine. This product is not intended to diagnose, treat, cure, or prevent any disease.

Q: Why is this product Health Canada approved?
A: This product holds NPN 80141963 from Health Canada, meaning it has been reviewed and approved for safety, efficacy, and quality as a natural health product. The NPN designation confirms that the approved uses (source of carnitine, supports energy metabolism, supports cognitive function) are backed by evidence reviewed by Health Canada, and that the product meets Canadian regulatory standards for ingredient quality, dosage, and labelling.

Supplement Facts

Serving Size: 1 Capsule (3 Capsules Per Day)

Servings Per Container: 40

Other Ingredients:

Hypromellose (Vegetable Capsule Shell), Microcrystalline Cellulose, Magnesium Stearate (Vegetable Source)

Clinical Research

Acetyl-L-carnitine improves aged brain function

Geriatrics & Gerontology International, 2010

This study examined the effects of Acetyl L-Carnitine supplementation on brain function in aging adults. The research found that ALCAR improved cognitive performance including attention, memory, and mental clarity in older participants. The mechanism identified was ALCAR's ability to cross the blood brain barrier, support neuronal mitochondrial energy metabolism, and contribute its acetyl group for acetylcholine synthesis directly supporting the Health Canada licensed uses of ALCAR for cognitive function and energy metabolism (NPN 80141963).

Acetyl-L-carnitine as a precursor of acetylcholine

Neurochemical Research, 1989

This foundational neurochemical study demonstrated that ALCAR crosses the blood-brain barrier and donates its acetyl group to choline via choline acetyltransferase (ChAT) to form acetylcholine in the brain. The study confirmed that ALCAR supplementation increased acetylcholine synthesis in brain tissue, directly establishing the biochemical mechanism by which ALCAR supports cognitive function the primary neurotransmitter pathway for attention, learning, and memory consolidation.

Randomized double blind placebo controlled trial of acetyl L-carnitine for cognitive decline in older adults

Dementia and Geriatric Cognitive Disorders, 2003

This randomized, double blind, placebo controlled trial administered ALCAR daily to older adults experiencing cognitive decline and measured cognitive performance over the study period. The study found that ALCAR supplementation significantly improved attention, memory, and overall cognitive function compared to placebo, supporting its role as a source of carnitine that crosses the blood-brain barrier to support acetylcholine synthesis and neuronal energy metabolism

Research information is provided for educational purposes and does not replace the product's approved label information.

Frequently Asked Questions

What is Acetyl L-Carnitine (ALCAR) and what does it do?

Acetyl L-Carnitine (ALCAR) is the acetylated form of L-carnitine that crosses the blood brain barrier efficiently. It supports energy metabolism by transporting long chain fatty acids into mitochondria for ATP production, and supports cognitive function by donating its acetyl group for acetylcholine synthesis in the brain. Licensed by Health Canada as a source of carnitine for energy metabolism and cognitive function (NPN 80141963). Each capsule provides 637.5mg ALCAR from 750mg ALCAR HCl. Suitable for adults seeking both energy and cognitive support. Consult a healthcare practitioner before use if pregnant, breastfeeding, or have kidney disease or a seizure disorder.

What is the difference between Acetyl L-Carnitine and regular L-Carnitine?

Standard L-carnitine supports peripheral energy metabolism by transporting fatty acids into mitochondria but does not cross the blood brain barrier efficiently and cannot contribute to acetylcholine synthesis. ALCAR crosses the blood brain barrier and donates its acetyl group for acetylcholine synthesis the primary neurotransmitter for attention, learning, and memory. ALCAR is the preferred form for cognitive function support. Suitable for adults seeking both brain and energy metabolism support. 637.5mg per capsule, 3 capsules per day.

Does Acetyl L-Carnitine help with brain fog and memory?

ALCAR crosses the blood-brain barrier and donates its acetyl group to choline via choline acetyltransferase (ChAT) to form acetylcholine the primary neurotransmitter for attention, learning, and memory consolidation. Licensed by Health Canada to support cognitive function (NPN 80141963). Suitable for adults seeking cognitive clarity and memory support. Consult a healthcare practitioner before use if you have a seizure disorder or are taking medications affecting the cholinergic system.

Does Acetyl L-Carnitine help with energy and fatigue?

ALCAR supports energy metabolism by facilitating the transport of long chain fatty acids across the inner mitochondrial membrane for beta oxidation and ATP production the primary energy pathway for the heart and skeletal muscle during sustained activity. Licensed by Health Canada to support energy metabolism (NPN 80141963). Suitable for adults experiencing fatigue or seeking sustained energy support. Consult a healthcare practitioner if you have kidney disease or are pregnant or breastfeeding.

Who should not take Acetyl L-Carnitine?

Ask a healthcare practitioner before use if you are pregnant or breastfeeding, have kidney disease, or have a seizure disorder. Gastrointestinal discomfort may occur taking with food may help. Suitable for healthy adults seeking energy metabolism and cognitive function support with no contraindicated conditions. Keep out of reach of children.

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Acetyl L-Carnitine 637.5mg | Source of Carnitine | Energy Metabolism and Cognitive Function | 120 Vegan Capsules

Source

What Is Acetyl L-Carnitine?

How Is ALCAR Different from Standard L-Carnitine?

Key Benefits

How It Works

Carnitine and Mitochondrial Fatty Acid Transport

ALCAR and the Blood-Brain Barrier

Acetylcholine Synthesis and Cognitive Function

Why ALCAR HCl and Not Free-Base ALCAR

Medicinal Ingredient (per capsule)

Per Daily Dose (3 Capsules)

Quality and Trust

Who This Is For

How to Use

Safety and Cautions

Ingredients

How to Use

FAQ

Acetyl L-Carnitine 637.5mg | Source of Carnitine | Energy Metabolism and Cognitive Function | 120 Vegan Capsules

Acetyl L-Carnitine 637.5mg | Source of Carnitine | Energy Metabolism and Cognitive Function | 120 Vegan Capsules

Source

What Is Acetyl L-Carnitine?

How Is ALCAR Different from Standard L-Carnitine?

Key Benefits

How It Works

Carnitine and Mitochondrial Fatty Acid Transport

ALCAR and the Blood-Brain Barrier

Acetylcholine Synthesis and Cognitive Function

Why ALCAR HCl and Not Free-Base ALCAR

Medicinal Ingredient (per capsule)

Per Daily Dose (3 Capsules)

Quality and Trust

Who This Is For

How to Use

Safety and Cautions

Ingredients

How to Use

FAQ

Supplement Facts

Supplement Facts

Clinical Research

Acetyl-L-carnitine improves aged brain function

Acetyl-L-carnitine as a precursor of acetylcholine

Randomized double blind placebo controlled trial of acetyl L-carnitine for cognitive decline in older adults

Frequently Asked Questions

Canadian-Made

Lab-Tested

Health Canada Approved

20 Years of Research

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