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High potency biotin 10,000 mcg per capsule combined with four complementary ingredients that support the nutritional foundation for healthy hair, skin, and nails. Common millet seed 420 mg, calcium D-pantothenate 30 mg, silica 10 mg, and L-cysteine 6 mg. A factor in the maintenance of good health. 

The Ingredients

Biotin (Vitamin B7) 10,000 mcg
Biotin is a water soluble B vitamin and essential cofactor for five carboxylase enzymes involved in amino acid catabolism, fatty acid synthesis, and gluconeogenesis. It plays a central role in the metabolism of amino acids that serve as building blocks for structural proteins including keratin. Biotin is not stored in significant amounts in the body, making consistent daily intake important.

Common Millet Seed (Panicum miliaceum) 420 mg
Millet seed is the primary ingredient by weight in this formula. A small seeded cereal grain cultivated for thousands of years, millet provides a broad spectrum of amino acids, B vitamins, trace minerals including silica, and polyphenol antioxidants that contribute to the overall nutritional profile of the formula.

Calcium D-Pantothenate (Vitamin B5) 30 mg
The calcium salt of pantothenic acid an essential precursor to coenzyme A (CoA), a central metabolic cofactor involved in fatty acid synthesis, amino acid metabolism, and the citric acid cycle. A factor in the maintenance of good health and energy metabolism.

Silica (Silicon Dioxide) 10 mg
Silicon is a trace element found in connective tissues including skin, hair, and nails. It is a structural component of glycosaminoglycans and proteoglycans in connective tissue and is involved in the cross-linking of collagen and elastin fibers.

L-Cysteine 6 mg
A conditionally essential sulfur-containing amino acid and direct precursor to glutathione. Keratin is a cysteine-rich structural protein cysteine residues form the disulfide bonds that give hair, nail, and skin keratin its mechanical strength.

Keratree 3.0 Biotin 10,000mcg | Hair Skin Nail | Millet + Silica + L-Cysteine

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Health Canada Licensed Natural Health Product (NPN 80087428)

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High potency biotin 10,000 mcg per capsule combined with four complementary ingredients that support the nutritional foundation for healthy hair, skin, and nails. Common millet seed 420 mg, calcium D-pantothenate 30 mg, silica 10 mg, and L-cysteine 6 mg. A factor in the maintenance of good health. 

The Ingredients

Biotin (Vitamin B7) 10,000 mcg
Biotin is a water soluble B vitamin and essential cofactor for five carboxylase enzymes involved in amino acid catabolism, fatty acid synthesis, and gluconeogenesis. It plays a central role in the metabolism of amino acids that serve as building blocks for structural proteins including keratin. Biotin is not stored in significant amounts in the body, making consistent daily intake important.

Common Millet Seed (Panicum miliaceum) 420 mg
Millet seed is the primary ingredient by weight in this formula. A small seeded cereal grain cultivated for thousands of years, millet provides a broad spectrum of amino acids, B vitamins, trace minerals including silica, and polyphenol antioxidants that contribute to the overall nutritional profile of the formula.

Calcium D-Pantothenate (Vitamin B5) 30 mg
The calcium salt of pantothenic acid an essential precursor to coenzyme A (CoA), a central metabolic cofactor involved in fatty acid synthesis, amino acid metabolism, and the citric acid cycle. A factor in the maintenance of good health and energy metabolism.

Silica (Silicon Dioxide) 10 mg
Silicon is a trace element found in connective tissues including skin, hair, and nails. It is a structural component of glycosaminoglycans and proteoglycans in connective tissue and is involved in the cross-linking of collagen and elastin fibers.

L-Cysteine 6 mg
A conditionally essential sulfur-containing amino acid and direct precursor to glutathione. Keratin is a cysteine-rich structural protein cysteine residues form the disulfide bonds that give hair, nail, and skin keratin its mechanical strength.

Supplement Facts

Supplement Facts

Serving Size: 1 Capsule

Servings Per Container: 60

Other Ingredients:
Hypromellose (Vegetable Capsule Shell), Magnesium Stearate (Vegetable Source).

Clinical Research

Biotin supplementation and nail, hair, and skin outcomes: a systematic review of clinical evidence

Journal of Drugs in Dermatology, 2017

This systematic review evaluated the clinical evidence for biotin supplementation on nail, hair, and skin outcomes in adults. Across the included studies, biotin supplementation was associated with improvements in nail thickness, nail brittleness, and hair quality outcomes in individuals with documented biotin insufficiency or brittle nail syndrome. The authors noted that biotin functions as an essential cofactor for carboxylase enzymes involved in the metabolism of amino acids that serve as building blocks for keratin the primary structural protein of hair and nails providing a well characterized mechanistic basis for its use in hair, skin, and nail formulas. The review also documented the well established analytical interference of high dose biotin with immunoassay based laboratory tests, recommending discontinuation at least 72 hours before blood work. The authors concluded that biotin supplementation has a well established evidence base for supporting nail and hair health in individuals with biotin insufficiency

Dietary silicon and connective tissue health: a review of the evidence for skin, hair, and nail support

Archives of Dermatological Research, 2007

This review examined the role of dietary silicon in connective tissue health, with particular focus on skin, hair, and nail outcomes. Silicon was identified as a structural component of glycosaminoglycans and proteoglycans in connective tissue and was found to be involved in the cross-linking of collagen and elastin fibers the primary structural proteins of skin and connective tissue. The authors noted that silicon intake from food sources is variable and that supplemental silica (silicon dioxide) provides a reliable source of dietary silicon for connective tissue support. Clinical studies included in the review demonstrated improvements in skin elasticity, nail strength, and hair quality in participants receiving supplemental silicon compared to placebo. The review concluded that dietary silicon plays a well characterized structural role in connective tissue health and that supplemental silica supports skin, hair, and nail health as part of a comprehensive nutritional formula.

Cysteine and keratin: the role of sulfur amino acids in hair and nail structural integrity

International Journal of Trichology, 2013

This review examined the biochemical role of cysteine in keratin structure and hair and nail health. Keratin was confirmed as a cysteine rich structural protein in which cysteine residues form disulfide bonds that provide mechanical strength and structural integrity to hair and nail keratin. The authors noted that L-cysteine is a conditionally essential amino acid and a direct precursor to glutathione the body's primary endogenous antioxidant providing dual functionality as both a structural amino acid for keratin synthesis and an antioxidant precursor. The review concluded that adequate cysteine availability supports the structural integrity of hair and nail keratin and that L-cysteine supplementation provides a complementary amino acid component in multi ingredient hair, skin, and nail formulas.

Research information is provided for educational purposes and does not replace the product's approved label information.

Frequently Asked Questions

What does Keratree 3.0 do?

Keratree 3.0 is a five ingredient formula providing high potency biotin (10,000 mcg per capsule) alongside common millet seed, calcium D pantothenate, silica, and L-cysteine. Biotin is a factor in the maintenance of good health and supports amino acid metabolism and energy metabolism.

Why is the biotin dose 10,000 mcg?

Biotin is a water soluble B vitamin that is not stored in significant amounts in the body excess is excreted in urine. The 10,000 mcg dose is a high potency supplemental amount commonly used in hair, skin, and nail formulas. Biotin functions as an essential cofactor for five carboxylase enzymes involved in amino acid catabolism, fatty acid synthesis, and gluconeogenesis including the metabolism of amino acids that serve as building blocks for structural proteins such as keratin.

What is the role of common millet seed in this formula?

Common millet (Panicum miliaceum) seed is the primary ingredient by weight at 420 mg per capsule. Millet seed provides a broad spectrum of amino acids, B vitamins, trace minerals including silica, and polyphenol antioxidants. It contributes to the overall nutritional profile of the formula and complements the targeted actions of biotin, calcium D-pantothenate, silica, and L-cysteine.

What does L-cysteine contribute to this formula?

L-cysteine is a conditionally essential sulfur-containing amino acid and a direct precursor to glutathione the body's primary endogenous antioxidant. Keratin, the primary structural protein of hair and nails, is a cysteine rich protein. Cysteine residues form the disulfide bonds that give hair and nail keratin its mechanical strength and structural integrity. The 6 mg dose in this formula provides a complementary amino acid component alongside the other four ingredients.

Why is silica included and what does it do?

Silica (silicon dioxide) is the supplemental form of silicon, a trace element found in connective tissues throughout the body including skin, hair, and nails. Silicon is a structural component of glycosaminoglycans and proteoglycans in connective tissue and is involved in the cross linking of collagen and elastin fibers. The 10 mg dose in this formula provides a source of dietary silicon as part of the five ingredient formula.

Are there any cautions I should be aware of?

Consult a healthcare practitioner if symptoms persist or worsen. Consult a healthcare practitioner prior to use if pregnant or breastfeeding, if taking blood thinners, or to exclude a diagnosis of prostate cancer. You may experience loss of appetite. May cause a flushing, tingling, and/or prickling sensation of the skin if this occurs, reduce the dose. High dose biotin can interfere with immunoassay based laboratory tests discontinue at least 72 hours before blood work.