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Nutridom Evening Primrose Oil 1000 mg organic cold pressed 120 veggie softgels
Evening Primrose Oil 1000 mg organic cold pressed GLA supplement bottle
Evening Primrose Oil veggie softgels 1000 mg organic cold pressed
Evening Primrose Oil GLA omega-6 fatty acid supplement 1000 mg
Evening Primrose Oil supplement for hormone balance and skin support
Nutridom Evening Primrose Oil 1000 mg supplement facts label 120 softgels
Nutridom Evening Primrose Oil 1000 mg organic cold pressed 120 veggie softgels

Organic Evening Primrose Oil 1000mg | 100mg GLA per Softgel | Cold Pressed | 120 Softgels

1000mg of certified organic evening primrose oil per softgel. Cold pressed from Oenothera biennis seed. Standardized to 100mg GLA. No heat. No solvents. No fillers.

Key Benefits

  • 1000mg organic cold pressed evening primrose oil per softgel Mechanical cold pressing retains the full fatty acid profile without heat degradation
  • 100mg GLA per softgel, guaranteed 200mg GLA per daily dose of 2 softgels
  • Hormonal balance and PMS support GLA is the precursor to prostaglandin E1, which regulates estrogen-sensitive tissue and luteal phase symptoms
  • Skin hydration and barrier repair GLA is incorporated into membrane phospholipids and ceramides that control transepidermal water loss
  • Natural anti-inflammatory pathway GLA converts to DGLA, which is channelled to prostaglandin E1 rather than pro-inflammatory arachidonic acid
  • Perimenopause and menopause support Prostaglandin E1 is involved in thermoregulation and mood signalling during hormonal transition
  • Certified organic and solvent free No pesticide residues, no hexane, non-GMO
  • Health Canada licensed NPN 80141539
  • Made in Canada GMP certified facility
  • 120 softgels 60 day supply at 2 softgels per day

What This Is

A single ingredient, cold pressed evening primrose seed oil supplement in a bovine gelatin softgel.

Each softgel contains 1000mg of certified organic Oenothera biennis seed oil with a fully disclosed fatty acid profile: 100mg GLA, approximately 720mg linoleic acid, and approximately 80mg oleic acid.

The bovine gelatin shell is oxygen-impermeable, protecting GLA from oxidative degradation throughout shelf life. Contains bovine gelatin. Not suitable for vegans or vegetarians.

Licensed by Health Canada under NPN 80141539. Manufactured in Canada to GMP standards.

The Science

Why the Body Cannot Always Make Enough GLA from Diet Alone

GLA is produced from dietary linoleic acid through the delta-6-desaturase enzyme. This step is consistently impaired by aging, elevated cortisol, insulin resistance, alcohol, and hormonal changes.

When delta-6-desaturase is underperforming, linoleic acid accumulates without converting to GLA. Evening primrose oil delivers GLA directly, bypassing this enzymatic bottleneck entirely.

The GLA to Prostaglandin E1 Pathway

Absorbed GLA is elongated to dihomo-gamma-linolenic acid (DGLA). DGLA is the direct substrate for prostaglandin E1 (PGE1) via cyclooxygenase-1.

PGE1 is a vasodilatory, platelet-inhibiting, and anti-inflammatory eicosanoid that regulates vascular tone, immune signalling, and reproductive tissue responses. Because DGLA is preferentially channelled toward PGE1 rather than pro-inflammatory arachidonic acid, GLA supplementation produces a net anti-inflammatory effect.

Cold Pressing Versus Solvent Extraction

Conventional seed oil production uses hexane at elevated temperatures. This oxidizes GLA, destroys tocopherols, and may leave trace solvent residues.

Cold pressing applies mechanical pressure at low temperatures with no heat and no chemicals. The result is a complete oil that retains its native fatty acid profile, antioxidant content, and phytosterol fraction.

Why Organic Source Matters for a Fatty Acid Supplement

GLA and linoleic acid are lipophilic and readily accumulate fat-soluble contaminants including organochlorine pesticides. Certified organic seed eliminates this pathway entirely.

Standardized to 100mg GLA per Softgel

Evening primrose oil naturally contains 8 to 10% GLA, but this varies with seed genetics and harvest conditions. A non-standardized 1000mg softgel may deliver as little as 80mg GLA.

This formulation guarantees a minimum of 100mg GLA per softgel across every batch.

Who This Is For

  • Not for use by individuals with seizure disorders or those taking phenothiazine medications
  • Not suitable for vegans or vegetarians (bovine gelatin softgel shell)
  • Adults seeking a standardized, organic GLA supplement for hormonal balance, skin health, or inflammatory support
  • Women managing PMS, perimenopause, or menopause-related symptoms who want a Health Canada licensed option

Evening Primrose Oil 1000mg | Organic Cold Pressed | GLA 100mg | 120 Softgels

$29.99
5.0 (2)

Health Canada Licensed Natural Health Product (NPN 80141539)

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Organic Evening Primrose Oil 1000mg | 100mg GLA per Softgel | Cold Pressed | 120 Softgels

1000mg of certified organic evening primrose oil per softgel. Cold pressed from Oenothera biennis seed. Standardized to 100mg GLA. No heat. No solvents. No fillers.

Key Benefits

  • 1000mg organic cold pressed evening primrose oil per softgel Mechanical cold pressing retains the full fatty acid profile without heat degradation
  • 100mg GLA per softgel, guaranteed 200mg GLA per daily dose of 2 softgels
  • Hormonal balance and PMS support GLA is the precursor to prostaglandin E1, which regulates estrogen-sensitive tissue and luteal phase symptoms
  • Skin hydration and barrier repair GLA is incorporated into membrane phospholipids and ceramides that control transepidermal water loss
  • Natural anti-inflammatory pathway GLA converts to DGLA, which is channelled to prostaglandin E1 rather than pro-inflammatory arachidonic acid
  • Perimenopause and menopause support Prostaglandin E1 is involved in thermoregulation and mood signalling during hormonal transition
  • Certified organic and solvent free No pesticide residues, no hexane, non-GMO
  • Health Canada licensed NPN 80141539
  • Made in Canada GMP certified facility
  • 120 softgels 60 day supply at 2 softgels per day

What This Is

A single ingredient, cold pressed evening primrose seed oil supplement in a bovine gelatin softgel.

Each softgel contains 1000mg of certified organic Oenothera biennis seed oil with a fully disclosed fatty acid profile: 100mg GLA, approximately 720mg linoleic acid, and approximately 80mg oleic acid.

The bovine gelatin shell is oxygen-impermeable, protecting GLA from oxidative degradation throughout shelf life. Contains bovine gelatin. Not suitable for vegans or vegetarians.

Licensed by Health Canada under NPN 80141539. Manufactured in Canada to GMP standards.

The Science

Why the Body Cannot Always Make Enough GLA from Diet Alone

GLA is produced from dietary linoleic acid through the delta-6-desaturase enzyme. This step is consistently impaired by aging, elevated cortisol, insulin resistance, alcohol, and hormonal changes.

When delta-6-desaturase is underperforming, linoleic acid accumulates without converting to GLA. Evening primrose oil delivers GLA directly, bypassing this enzymatic bottleneck entirely.

The GLA to Prostaglandin E1 Pathway

Absorbed GLA is elongated to dihomo-gamma-linolenic acid (DGLA). DGLA is the direct substrate for prostaglandin E1 (PGE1) via cyclooxygenase-1.

PGE1 is a vasodilatory, platelet-inhibiting, and anti-inflammatory eicosanoid that regulates vascular tone, immune signalling, and reproductive tissue responses. Because DGLA is preferentially channelled toward PGE1 rather than pro-inflammatory arachidonic acid, GLA supplementation produces a net anti-inflammatory effect.

Cold Pressing Versus Solvent Extraction

Conventional seed oil production uses hexane at elevated temperatures. This oxidizes GLA, destroys tocopherols, and may leave trace solvent residues.

Cold pressing applies mechanical pressure at low temperatures with no heat and no chemicals. The result is a complete oil that retains its native fatty acid profile, antioxidant content, and phytosterol fraction.

Why Organic Source Matters for a Fatty Acid Supplement

GLA and linoleic acid are lipophilic and readily accumulate fat-soluble contaminants including organochlorine pesticides. Certified organic seed eliminates this pathway entirely.

Standardized to 100mg GLA per Softgel

Evening primrose oil naturally contains 8 to 10% GLA, but this varies with seed genetics and harvest conditions. A non-standardized 1000mg softgel may deliver as little as 80mg GLA.

This formulation guarantees a minimum of 100mg GLA per softgel across every batch.

Who This Is For

  • Not for use by individuals with seizure disorders or those taking phenothiazine medications
  • Not suitable for vegans or vegetarians (bovine gelatin softgel shell)
  • Adults seeking a standardized, organic GLA supplement for hormonal balance, skin health, or inflammatory support
  • Women managing PMS, perimenopause, or menopause-related symptoms who want a Health Canada licensed option

Supplement Facts

Supplement Facts

Serving Size: 2 Softgels

Servings Per Container: 60

Other Ingredients:
d-Alpha Tocopherol (Vitamin E), Non-GMO Tapioca Gelatin (Softgel Shell), Glycerin, Purified Water

Clinical Research

Evening primrose oil and treatment of premenstrual syndrome

Reviews in Pure and Applied Pharmacological Sciences, 1983

This foundational review examined the clinical evidence for evening primrose oil GLA supplementation in premenstrual syndrome (PMS). The paper proposed that PMS symptoms arise partly from impaired delta 6 desaturase activity reducing endogenous GLA and prostaglandin E1 (PGE1) production and that direct GLA supplementation via evening primrose oil restores PGE1 signalling in estrogen sensitive tissue. The review synthesized early clinical trial data showing improvements in PMS symptom scores including breast tenderness, mood changes, and bloating with evening primrose oil supplementation, establishing the GLA to PGE1 pathway as the primary mechanism of action for hormonal balance support.

The use of gamma linolenic acid in the treatment of atopic dermatitis

British Journal of Dermatology, 1989

This large randomized, double blind, placebo controlled multicentre trial administered evening primrose oil (providing GLA) to patients with atopic dermatitis and measured skin barrier function, transepidermal water loss, and symptom scores. The study found that GLA supplementation significantly improved overall symptom scores, skin hydration, and barrier integrity compared to placebo. The authors attributed the benefit to GLA's incorporation into membrane phospholipids and ceramides the structural lipids controlling transepidermal water loss directly supporting evening primrose oil's role in skin hydration and barrier repair.

Evening primrose oil for hot flashes in perimenopausal and menopausal women: a systematic review and meta analysis

Menopause, 2013

This systematic review and meta analysis examined the clinical evidence for evening primrose oil supplementation in perimenopausal and menopausal women experiencing hot flashes and vasomotor symptoms. The analysis found that evening primrose oil supplementation significantly reduced the frequency and severity of hot flashes compared to placebo, with the effect attributed to GLA's role as a precursor to prostaglandin E1 which is involved in thermoregulation and mood signalling during hormonal transition. The findings directly support evening primrose oil's use for perimenopause and menopause support.

Research information is provided for educational purposes and does not replace the product's approved label information.

Frequently Asked Questions

What is evening primrose oil and what does it do?

Evening primrose oil is a cold pressed seed oil fromOenothera biennis a flowering plant native to North America. It is one of the richest plant sources of gamma linolenic acid (GLA), an omega-6 fatty acid that the body uses to produce prostaglandin E1 (PGE1) a vasodilatory, anti-inflammatory eicosanoid involved in hormonal regulation, skin barrier function, and immune signalling.

What is GLA and why does evening primrose oil contain it?

GLA (gamma-linolenic acid) is an omega-6 fatty acid produced in the body from dietary linoleic acid through the delta-6-desaturase enzyme. This conversion step is consistently impaired by aging, elevated cortisol, insulin resistance, alcohol, and hormonal changes meaning many adults cannot produce adequate GLA from diet alone. Evening primrose oil delivers GLA directly from the seed, bypassing this enzymatic bottleneck entirely.

What is evening primrose oil good for?

Evening primrose oil GLA is the precursor to prostaglandin E1 (PGE1), which regulates estrogen sensitive tissue, luteal phase symptoms, vascular tone, and inflammatory signalling. It is most commonly used for hormonal balance and PMS support, skin hydration and barrier repair, perimenopause and menopause support, and as a natural anti-inflammatory pathway supplement. GLA is incorporated into membrane phospholipids and ceramides that control transepidermal water loss supporting skin hydration from within.

How does evening primrose oil help with PMS and hormonal balance?

GLA from evening primrose oil is elongated to dihomo gamma linolenic acid (DGLA), which is the direct substrate for prostaglandin E1 (PGE1) via cyclooxygenase-1. PGE1 regulates estrogen sensitive tissue responses and luteal phase symptoms associated with PMS including breast tenderness, mood changes, and cramping. Because DGLA is preferentially channelled toward PGE1 rather than pro inflammatory arachidonic acid, GLA supplementation produces a net anti-inflammatory and hormone modulating effect.

Is evening primrose oil good for skin?

Yes. GLA from evening primrose oil is incorporated into membrane phospholipids and ceramides The structural lipids that form the skin barrier and control transepidermal water loss (TEWL). When GLA is deficient, the skin barrier becomes compromised, leading to dryness, sensitivity, and impaired repair. Supplementing with GLA supports skin hydration, barrier integrity, and inflammatory skin conditions from within.

Why is cold pressed evening primrose oil better than solvent extracted?

Conventional seed oil production uses hexane solvent at elevated temperatures. This process oxidizes GLA, destroys tocopherols (vitamin E), and may leave trace solvent residues in the finished oil. Cold pressing applies mechanical pressure at low temperatures with no heat and no chemicals retaining the native fatty acid profile, antioxidant content, and phytosterol fraction of the seed.

Who should not take evening primrose oil?

Do not use if you have a seizure disorder or are taking phenothiazine medications evening primrose oil may lower the seizure threshold in susceptible individuals. Consult a healthcare practitioner before use if you are pregnant, breastfeeding, have a diagnosed health condition, or are taking prescription medications including anticoagulants. Stop use and consult a healthcare practitioner if headache, nausea, or loose stools occur. Ask a healthcare practitioner for use beyond 12 weeks. Keep out of reach of children.

Canadian-Made

Lab-Tested

Health Canada Approved

20 Years of Research

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