Black Maca L-Arginine | Nitric Oxide Precursor and Adaptogen | Circulation and Performance | 90 Capsules

Each capsule delivers 400mg of L-Arginine (as L-Arginine monohydrochloride) and 200mg of black maca root extract (Lepidium meyenii, 4:1, QCE 800mg). L-Arginine is the primary dietary precursor to nitric oxide, the signalling molecule that causes vasodilation by relaxing vascular smooth muscle. Black maca contributes the unique macamide bioactives of Lepidium meyenii associated with energy and vitality.

Helps support cardiovascular health. Helps support healthy circulation. Health Canada licensed NPN 80144129. Made in Canada. 90 capsules, approximately 22 day supply at the suggested dose of 4 capsules per day.

Source

L-Arginine source: L-Arginine monohydrochloride, a pharmaceutical-grade salt form of the amino acid L-Arginine. The monohydrochloride form is more stable and has better solubility than free-base L-Arginine. L-Arginine is a conditionally essential amino acid synthesized endogenously from citrulline and also obtained from dietary protein sources including meat, poultry, fish, dairy, and legumes.

Black maca source: Lepidium meyenii (black variety) root, grown at high altitude in the Peruvian Andes (3800 to 4500 metres above sea level). Black maca is the rarest maca colour variety, comprising approximately 15% of the Peruvian maca harvest. The 4:1 concentrated extract means 4 grams of raw black maca root were used to produce each gram of extract, providing QCE 800mg of raw root equivalent per 200mg capsule.

What Is the Difference Between Black Maca and Regular Maca?

Maca (Lepidium meyenii) is grown in three colour varieties: yellow (most common, approximately 60% of harvest), red (approximately 25%), and black (rarest, approximately 15%). Black maca has been specifically studied for its energy and vitality supporting properties and contains the highest concentration of macamides and macaenes, the benzylated fatty acid bioactives unique to Lepidium meyenii. This formula uses black maca exclusively, not a blend of maca colours.

What Is L-Arginine and How Does It Support Circulation?

L-Arginine is the primary substrate for nitric oxide synthase (NOS), the enzyme that produces nitric oxide (NO) in the body. Nitric oxide diffuses into vascular smooth muscle cells, activates soluble guanylate cyclase, increases cyclic GMP (cGMP), and causes smooth muscle relaxation and vasodilation. This vasodilation increases blood vessel diameter, reduces vascular resistance, and supports healthy blood flow and circulation. L-Arginine availability is a key factor in endothelial NOS (eNOS) activity, the primary source of nitric oxide in the cardiovascular system.

Key Benefits

• Helps support cardiovascular health Health Canada licensed claim under NPN 80144129
• Helps support healthy circulation Health Canada licensed claim under NPN 80144129
• L-Arginine 400mg per capsule As L-Arginine monohydrochloride | Primary dietary precursor to nitric oxide | Supports vasodilation via the eNOS pathway
• Black maca root extract 200mg per capsule Lepidium meyenii, 4:1 concentrate, QCE 800mg | Rarest maca variety | Highest macamide and macaene content of the three maca colours
• Dual mechanism formula L-Arginine via the nitric oxide pathway for circulation | Black maca via macamide bioactives for energy and vitality
• 1600mg L-Arginine and QCE 3200mg black maca per day At the suggested dose of 4 capsules per day
• Vegan capsule Hypromellose shell, no gelatin or animal derived ingredients
• Health Canada licensed NPN 80144129 | GMP certified | Made in Canada
• 90 capsules Approximately 22 day supply at 4 capsules per day

How It Works

L-Arginine and the Nitric Oxide Pathway

Nitric oxide synthase enzymes (endothelial NOS, neuronal NOS, and inducible NOS) convert L-Arginine to L-Citrulline, releasing nitric oxide as a byproduct. Nitric oxide diffuses into adjacent vascular smooth muscle cells, activates soluble guanylate cyclase, increases cyclic GMP (cGMP), and activates protein kinase G. Protein kinase G phosphorylates myosin light chain kinase, reducing its activity and causing smooth muscle relaxation and vasodilation. This increases blood vessel diameter, reduces vascular resistance, and supports healthy blood flow.

Why L-Arginine Monohydrochloride

This formula uses L-Arginine as the monohydrochloride salt rather than free-base L-Arginine. The monohydrochloride form is more stable, has better solubility, and is the form used in pharmaceutical-grade L-Arginine preparations. It provides the same biologically active L-Arginine amino acid as the free-base form with improved stability and consistency.

Black Maca and Macamide Bioactives

The primary bioactive compounds in black maca are macamides and macaenes, benzylated fatty acids and their amides that are unique to Lepidium meyenii and not found in any other plant. These compounds are the primary marker compounds for maca quality and are associated with maca's energy and vitality properties. The 4:1 concentration ratio concentrates macamides and other bioactives relative to raw maca powder, delivering QCE 800mg of raw root equivalent per 200mg capsule.

Complementary Dual Mechanism

L-Arginine and black maca address circulation and performance through distinct and complementary mechanisms. L-Arginine works through the nitric oxide pathway to support vasodilation and healthy blood flow. Black maca contributes its unique macamide bioactives associated with energy and vitality. Together they form a dual-ingredient formula addressing both the circulatory and the adaptogenic dimensions of physical performance support.

Understanding QCE: Maca Extract Potency

QCE (Quantity of Crude Equivalent) is the Health Canada standardized notation for expressing the raw material equivalent of a concentrated herbal extract. A 4:1 extract means 4 grams of raw black maca root were used to produce 1 gram of extract. Each 200mg capsule contains the concentrated bioactives from 800mg of raw black maca root (QCE 800mg). At 4 capsules per day, the daily maca dose is QCE 3200mg of raw black maca root.

Medicinal Ingredients (per capsule)

• L-Arginine (as L-Arginine monohydrochloride) 400mg Source: pharmaceutical-grade amino acid salt | Nitric oxide precursor | NPN 80144129
• Black Maca Root Extract (Lepidium meyenii, root, 4:1) 200mg QCE 800mg | Source: high-altitude Peruvian Andes (3800 to 4500m) | Rarest maca variety | NPN 80144129

Non-medicinal ingredients: Hypromellose (vegetable capsule shell), microcrystalline cellulose, magnesium stearate (vegetable source).

Per Daily Dose (4 Capsules)

• L-Arginine (as L-Arginine monohydrochloride): 1600mg
• Black Maca Root Extract (4:1): 800mg | QCE 3200mg raw black maca root

Quality and Trust

• NPN 80144129 Licensed by Health Canada as a Natural Health Product
• Made in Canada GMP certified facility under Health Canada oversight
• Black maca exclusively Lepidium meyenii black variety, not a blend of maca colours
• 4:1 concentrated extract QCE 800mg raw root equivalent per 200mg capsule
• Pharmaceutical-grade L-Arginine monohydrochloride Superior stability versus free-base L-Arginine
• Vegan capsule Hypromellose shell, no gelatin or animal derived ingredients
• 90 capsules Approximately 22 day supply at 4 capsules per day

Who This Is For

• Discontinue use 2 weeks prior to any scheduled surgery
• Consult a healthcare practitioner before use if you are taking blood pressure medications, as L-Arginine's vasodilatory effects may potentiate antihypertensive medications
• Consult a healthcare practitioner before use if you have kidney or liver conditions, are pregnant or breastfeeding, or have thyroid conditions (maca belongs to the Brassicaceae family and contains glucosinolates)
• Adults seeking cardiovascular health and healthy circulation support from a nitric oxide precursor combined with black maca adaptogen
• Those wanting a dual-mechanism formula addressing both the circulatory (L-Arginine, nitric oxide) and adaptogenic (black maca, macamides) dimensions of physical performance
• Vegans and vegetarians seeking a plant-capsule formula

How to Use

Adults: Take 2 capsules, 2 times per day (4 capsules per day), or as directed by a healthcare practitioner.

At 4 capsules per day, 90 capsules provides approximately a 22 day supply.

Safety and Cautions

Consult a healthcare practitioner before use if you are taking blood pressure medications, have kidney or liver conditions, are pregnant or breastfeeding, or have thyroid conditions. Maca belongs to the Brassicaceae family and contains glucosinolates; individuals with thyroid conditions should consult a healthcare practitioner before use. Discontinue use 2 weeks prior to any scheduled surgery. Store in a cool, dry place away from direct sunlight. Keep bottle tightly sealed. Do not use if the seal is broken or missing. Keep out of reach of children.

NPN 80144129. This product is not intended to diagnose, treat, cure, or prevent any disease. All health claims are consistent with Health Canada's Natural Health Products Regulations.