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Conjugated linoleic acid (CLA) 1,000 mg per softgel, 4,000 mg per day. A source of omega-6 fatty acids for the maintenance of good health. CLA is a naturally occurring polyunsaturated fatty acid in the omega-6 family, found in the meat and dairy of ruminant animals and produced here as synthetic CLA chemically identical to food-derived CLA, with a consistent isomer profile in every softgel. 

What Is CLA?

CLA is a group of positional and geometric isomers of linoleic acid an omega-6 essential fatty acid in which the double bonds are conjugated rather than separated by a methylene group as in standard linoleic acid. It occurs naturally in ruminant derived foods through biohydrogenation of linoleic acid by rumen bacteria, and is found in highest concentrations in grass fed beef and full fat dairy from pasture-raised animals. Modern diets have shifted substantially away from these traditional sources, lowering average dietary CLA intake.

CLA 1,000mg | Conjugated Linoleic Acid | Omega-6 Fatty Acids

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Health Canada Licensed Natural Health Product (NPN 80043192)

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Conjugated linoleic acid (CLA) 1,000 mg per softgel, 4,000 mg per day. A source of omega-6 fatty acids for the maintenance of good health. CLA is a naturally occurring polyunsaturated fatty acid in the omega-6 family, found in the meat and dairy of ruminant animals and produced here as synthetic CLA chemically identical to food-derived CLA, with a consistent isomer profile in every softgel. 

What Is CLA?

CLA is a group of positional and geometric isomers of linoleic acid an omega-6 essential fatty acid in which the double bonds are conjugated rather than separated by a methylene group as in standard linoleic acid. It occurs naturally in ruminant derived foods through biohydrogenation of linoleic acid by rumen bacteria, and is found in highest concentrations in grass fed beef and full fat dairy from pasture-raised animals. Modern diets have shifted substantially away from these traditional sources, lowering average dietary CLA intake.

Supplement Facts

Supplement Facts

Serving Size: 2 Softgels

Servings Per Container: 15

Ingredient
Amount Per
Serving
% Daily
Value
CLA (Conjugated Linoleic Acid, Synthetic)
2,000 mg

† Daily Value not established.

Other Ingredients:
Gelatin, Glycerin, Distilled Water.

Clinical Research

Effects of conjugated linoleic acid supplementation on body composition: a meta analysis of randomized controlled trials

American Journal of Clinical Nutrition, 2007

This meta analysis pooled data from randomized controlled trials examining the effects of CLA supplementation on body composition in humans. The analysis found that CLA supplementation was associated with a modest but statistically significant reduction in body fat mass compared to placebo, with no significant effect on lean body mass. The authors noted that the t10,c12 CLA isomer was identified as the primary isomer responsible for the observed effects on fat mass, while the c9,t11 isomer demonstrated less pronounced effects on body composition. The review concluded that CLA supplementation produces consistent, reproducible effects on body fat mass in humans across a range of doses and supplementation periods, consistent with its classification as an omega-6 fatty acid with established physiological effects. The authors noted that the magnitude of effect was modest and that CLA supplementation should be considered as part of a comprehensive approach to body composition management rather than as a standalone intervention.

Conjugated linoleic acid supplementation and lipid metabolism in healthy adults: a randomized, double blind, placebo controlled trial

Lipids, 2004

This randomized, double blind, placebo controlled trial investigated the effects of CLA supplementation on lipid metabolism parameters in healthy adults over a 12-week supplementation period. Participants receiving CLA demonstrated changes in fatty acid composition of plasma phospholipids consistent with incorporation of CLA isomers into cellular membranes, confirming bioavailability and tissue uptake of supplemental CLA. The study examined the c9,t11 and t10,c12 CLA isomers separately and found distinct metabolic effects for each isomer, with the c9,t11 isomer demonstrating effects consistent with its role as a source of omega-6 fatty acids in lipid metabolism. The authors concluded that CLA supplementation is bioavailable in humans, is incorporated into plasma phospholipids and cellular membranes, and produces measurable changes in fatty acid metabolism parameters, consistent with its classification as a source of omega-6 fatty acids for the maintenance of good health.

Biological activity of conjugated linoleic acid isomers: mechanisms of action and implications for supplementation

Journal of Nutritional Biochemistry, 2010

This mechanistic review examined the distinct biological activities of the primary CLA isomers c9,t11 (rumenic acid) and t10,c12 with particular focus on their roles in fatty acid metabolism, cellular membrane composition, and signaling pathways. The c9,t11 isomer, which constitutes the majority of CLA in ruminant derived foods and is the predominant naturally occurring form, was found to exert its effects primarily through incorporation into cellular membrane phospholipids and modulation of eicosanoid signaling pathways as a component of the omega-6 fatty acid metabolic network. The t10,c12 isomer demonstrated distinct effects on adipocyte metabolism through modulation of peroxisome proliferator activated receptors (PPARs) and other transcription factors involved in lipid metabolism. The authors concluded that CLA isomers have well characterized mechanisms of action in human fatty acid metabolism and that synthetic CLA, which provides a standardized mixture of c9,t11 and t10,c12 isomers, is an effective and bioavailable source of omega-6 fatty acids with consistent and reproducible biological activity.

Research information is provided for educational purposes and does not replace the product's approved label information.

Frequently Asked Questions

What is CLA 1,000mg?

CLA stands for conjugated linoleic acid, a naturally occurring type of omega-6 fatty acid found in small amounts in foods such as meat and dairy products. This supplement provides 1,000 mg of CLA per specified serving.

What is the difference between synthetic CLA and food derived CLA?

CLA occurs naturally in the meat and dairy products of ruminant animals (cattle, sheep, goats) through biohydrogenation of linoleic acid by rumen bacteria. The CLA in this product is synthetic produced through chemical synthesis rather than extracted from animal sources. Synthetic CLA is chemically identical to food-derived CLA and provides the same isomers (primarily c9,t11 and t10,c12 CLA). Synthetic production ensures a consistent and standardized isomer profile and potency in every softgel, which can vary in food derived sources depending on the animal's diet, breed, and processing method.

Why supplement CLA rather than getting it from food?

The primary food sources of CLA are grass fed beef and full fat dairy from pasture raised ruminant animals. Modern food systems have shifted substantially toward grain fed livestock and reduced fat dairy products, which contain significantly lower concentrations of CLA than their traditional counterparts. For adults who follow lower fat diets, limit red meat and dairy, or want a consistent and measured daily intake of this omega-6 fatty acid, a CLA supplement provides a convenient and reliable source as part of a balanced nutritional routine.

What is Conjugated Linoleic Acid used for?

CLA is commonly used in supplements designed to complement active lifestyles, exercise programs, and healthy body composition goals.

What are the benefits of CLA supplements?

CLA supplements are commonly used by adults interested in fitness, body composition, and nutritional support alongside a balanced diet and regular physical activity.

Who may consider taking CLA 1,000mg?

CLA may be suitable for adults looking for a convenient source of conjugated linoleic acid to complement an active lifestyle, regular exercise, and healthy body composition goals.