L-Citrulline 750mg | Circulation and Nitric Oxide Support | Free Form Amino Acid | 120 Vcaps
Each capsule delivers 750mg of pure free form L-citrulline, a non-essential amino acid that serves as a precursor to L-arginine and nitric oxide in the body. L-citrulline is absorbed intact from the gastrointestinal tract and converted to L-arginine in the kidneys, supporting sustained L-arginine availability and nitric oxide production. Supports healthy circulation and exercise performance as part of a balanced diet and active lifestyle.
Who This Is For
- Athletes and active adults seeking circulation and exercise performance support from a Health Canada licensed free form L-citrulline supplement
- Those who prefer L-citrulline over L-arginine for its superior bioavailability and more sustained plasma L-arginine elevation
- Those wanting a clean, vegan, non-GMO amino acid supplement with no artificial additives
- Those seeking a Canadian made supplement with full Health Canada licensing
Where Does L-Citrulline Come From?
L-citrulline was first isolated from watermelon (Citrullus vulgaris) in 1930, which remains one of the richest natural food sources of L-citrulline. L-citrulline used in supplements is synthetically produced by fermentation or chemical synthesis, yielding a compound chemically identical to the L-citrulline found naturally in watermelon and other foods.
Why Is L-Citrulline Better Than L-Arginine for Nitric Oxide Support?
L-arginine is the direct substrate for nitric oxide synthase (NOS), the enzyme that produces nitric oxide. However, oral L-arginine supplementation is limited by significant first-pass metabolism in the intestinal wall and liver, where the enzyme arginase rapidly degrades L-arginine before it reaches systemic circulation. L-citrulline bypasses this limitation entirely because it is not a substrate for arginase. It is absorbed intact and converted to L-arginine in the kidneys, where it enters systemic circulation. Research comparing oral L-citrulline to oral L-arginine consistently shows that L-citrulline produces greater and more sustained increases in plasma L-arginine levels than equivalent doses of L-arginine itself. This is why L-citrulline is the preferred form for nitric oxide and circulation support.
Key Benefits
- Circulation support L-citrulline supports the L-citrulline to L-arginine to nitric oxide pathway. Nitric oxide is a potent vasodilator that relaxes vascular smooth muscle, supporting healthy blood vessel tone and circulation. Health Canada licensed use under NPN 80139498.
- Exercise performance support Supports nitric oxide production and healthy circulation to working muscles during exercise. Also supports urea cycle function and ammonia clearance, a key contributor to exercise-induced fatigue. Health Canada licensed use under NPN 80139498.
- Superior bioavailability vs. L-arginine Bypasses first-pass arginase metabolism. Greater and more sustained plasma L-arginine elevation than equivalent oral L-arginine doses.
- 750mg free form L-citrulline per capsule 3000mg per daily dose of 4 capsules (2 capsules twice daily).
- Health Canada licensed NPN 80139498. Made in Canada.
- Vegan and non-GMO Gluten free, soy free. Hypromellose vegan capsule, no gelatin.
- 120 capsules 30 day supply at 4 capsules per day.
Medicinal Ingredients (per capsule)
- L-Citrulline (free form) 750mg
Non-medicinal ingredients: Hypromellose (vegetable capsule shell), microcrystalline cellulose, magnesium stearate. Non-GMO, gluten free, soy free. No artificial colours, flavours, sweeteners, or preservatives.
Quality and Trust
- NPN 80139498 Licensed by Health Canada as a Natural Health Product
- Made in Canada Quality controlled facility under federal oversight
- Pure free form L-citrulline Pharmaceutical grade purity. Synthetically produced for consistent potency.
- Vegan capsule Hypromellose, no gelatin or animal-derived ingredients
- Non-GMO, gluten free, soy free No artificial colours, flavours, sweeteners, or preservatives
- 120 capsules 30 day supply at 4 capsules per day
How to Take L-Citrulline
Adults: Take 2 capsules 2 times per day, with or without food. Commonly taken before exercise for circulation and performance support. At 4 capsules per day, one bottle of 120 capsules provides a 30 day supply.
Storage
Store in a cool, dry place away from direct sunlight and moisture. Keep the bottle tightly sealed after each use. Do not use if the seal is broken or missing. Keep out of reach of children.
Safety and Cautions
Ask a healthcare practitioner before use if you are taking medication for cardiovascular diseases, erectile dysfunction, or blood thinners. Ask a healthcare practitioner before use if you have a cardiovascular disease and are attempting an increase in physical activity. Ask a healthcare practitioner before use if you are pregnant or breastfeeding. Keep out of reach of children.
NPN 80139498. All health claims are consistent with Health Canada's Natural Health Products Regulations.
L-Citrulline 750mg | Circulation and Nitric Oxide Support | Free Form Amino Acid | 120 Vcaps
Each capsule delivers 750mg of pure free form L-citrulline, a non-essential amino acid that serves as a precursor to L-arginine and nitric oxide in the body. L-citrulline is absorbed intact from the gastrointestinal tract and converted to L-arginine in the kidneys, supporting sustained L-arginine availability and nitric oxide production. Supports healthy circulation and exercise performance as part of a balanced diet and active lifestyle.
Who This Is For
- Athletes and active adults seeking circulation and exercise performance support from a Health Canada licensed free form L-citrulline supplement
- Those who prefer L-citrulline over L-arginine for its superior bioavailability and more sustained plasma L-arginine elevation
- Those wanting a clean, vegan, non-GMO amino acid supplement with no artificial additives
- Those seeking a Canadian made supplement with full Health Canada licensing
Where Does L-Citrulline Come From?
L-citrulline was first isolated from watermelon (Citrullus vulgaris) in 1930, which remains one of the richest natural food sources of L-citrulline. L-citrulline used in supplements is synthetically produced by fermentation or chemical synthesis, yielding a compound chemically identical to the L-citrulline found naturally in watermelon and other foods.
Why Is L-Citrulline Better Than L-Arginine for Nitric Oxide Support?
L-arginine is the direct substrate for nitric oxide synthase (NOS), the enzyme that produces nitric oxide. However, oral L-arginine supplementation is limited by significant first-pass metabolism in the intestinal wall and liver, where the enzyme arginase rapidly degrades L-arginine before it reaches systemic circulation. L-citrulline bypasses this limitation entirely because it is not a substrate for arginase. It is absorbed intact and converted to L-arginine in the kidneys, where it enters systemic circulation. Research comparing oral L-citrulline to oral L-arginine consistently shows that L-citrulline produces greater and more sustained increases in plasma L-arginine levels than equivalent doses of L-arginine itself. This is why L-citrulline is the preferred form for nitric oxide and circulation support.
Key Benefits
- Circulation support L-citrulline supports the L-citrulline to L-arginine to nitric oxide pathway. Nitric oxide is a potent vasodilator that relaxes vascular smooth muscle, supporting healthy blood vessel tone and circulation. Health Canada licensed use under NPN 80139498.
- Exercise performance support Supports nitric oxide production and healthy circulation to working muscles during exercise. Also supports urea cycle function and ammonia clearance, a key contributor to exercise-induced fatigue. Health Canada licensed use under NPN 80139498.
- Superior bioavailability vs. L-arginine Bypasses first-pass arginase metabolism. Greater and more sustained plasma L-arginine elevation than equivalent oral L-arginine doses.
- 750mg free form L-citrulline per capsule 3000mg per daily dose of 4 capsules (2 capsules twice daily).
- Health Canada licensed NPN 80139498. Made in Canada.
- Vegan and non-GMO Gluten free, soy free. Hypromellose vegan capsule, no gelatin.
- 120 capsules 30 day supply at 4 capsules per day.
Medicinal Ingredients (per capsule)
- L-Citrulline (free form) 750mg
Non-medicinal ingredients: Hypromellose (vegetable capsule shell), microcrystalline cellulose, magnesium stearate. Non-GMO, gluten free, soy free. No artificial colours, flavours, sweeteners, or preservatives.
Quality and Trust
- NPN 80139498 Licensed by Health Canada as a Natural Health Product
- Made in Canada Quality controlled facility under federal oversight
- Pure free form L-citrulline Pharmaceutical grade purity. Synthetically produced for consistent potency.
- Vegan capsule Hypromellose, no gelatin or animal-derived ingredients
- Non-GMO, gluten free, soy free No artificial colours, flavours, sweeteners, or preservatives
- 120 capsules 30 day supply at 4 capsules per day
How to Take L-Citrulline
Adults: Take 2 capsules 2 times per day, with or without food. Commonly taken before exercise for circulation and performance support. At 4 capsules per day, one bottle of 120 capsules provides a 30 day supply.
Storage
Store in a cool, dry place away from direct sunlight and moisture. Keep the bottle tightly sealed after each use. Do not use if the seal is broken or missing. Keep out of reach of children.
Safety and Cautions
Ask a healthcare practitioner before use if you are taking medication for cardiovascular diseases, erectile dysfunction, or blood thinners. Ask a healthcare practitioner before use if you have a cardiovascular disease and are attempting an increase in physical activity. Ask a healthcare practitioner before use if you are pregnant or breastfeeding. Keep out of reach of children.
NPN 80139498. All health claims are consistent with Health Canada's Natural Health Products Regulations.
Canadian-Made
Lab-Tested
Health Canada Approved
