Glucosamine Sulfate 500mg + MSM 500mg per Capsule | 1,500mg Each per Daily Dose | Health Canada Approved (NPN 80058087).

Each capsule contains Glucosamine (Glucosamine sulfate) 500mg and MSM (Methylsulfonylmethane, Dimethyl sulfone) 500mg. Helps to relieve joint pain associated with osteoarthritis (of the knee). Helps to protect against the deterioration of cartilage. A factor in maintaining healthy cartilage and/or joint health. Health Canada approved (NPN 80058087). Adults: 1 capsule, 3 times per day with food. Avoid taking at bedtime. Use for a minimum of 1 month to see beneficial effects. Non-GMO. Made in Canada. 300 capsules (100 day supply at 3 capsules per day).

NPN Approved Uses

• Helps to relieve joint pain associated with osteoarthritis (of the knee).
• Helps to protect against the deterioration of cartilage.
• A factor in maintaining healthy cartilage and/or joint health.

Key Facts

• Glucosamine (Glucosamine sulfate): 500mg per capsule (1,500mg per daily dose)
• MSM (Methylsulfonylmethane): 500mg per capsule (1,500mg per daily dose)
• Adults: 1 capsule, 3 times per day with food
• Avoid taking at bedtime
• Use for a minimum of 1 month to see beneficial effects
• Health Canada approved (NPN 80058087)
• 300 capsules (100 day supply at 3 capsules per day)
• Made in Canada

What This Product Does

This formula helps to relieve joint pain associated with osteoarthritis (of the knee). It helps to protect against the deterioration of cartilage. It is a factor in maintaining healthy cartilage and/or joint health. These are the Health Canada approved uses (NPN 80058087). This product is not intended to diagnose, treat, cure, or prevent any disease.

What Is Glucosamine?

Glucosamine is an amino sugar — a sugar molecule with an amino group attached. It is a natural component of cartilage, specifically a building block of glycosaminoglycans (GAGs), which are the long chains of sugar molecules that form the structural matrix of cartilage. Cartilage is the connective tissue that cushions the ends of bones in joints. Glycosaminoglycans give cartilage its ability to absorb compressive forces.

The body produces glucosamine endogenously, but production may decline with age. Supplemental glucosamine is typically derived from crustacean shells (chitin) or from bacterial fermentation of grains. This formula uses glucosamine sulfate specifically.

Why Glucosamine Sulfate Specifically?

There are two main forms of glucosamine used in supplements: glucosamine sulfate and glucosamine hydrochloride (HCl). Glucosamine sulfate provides both glucosamine and sulfate. Sulfate is a component of cartilage proteoglycans the large molecules that give cartilage its water-retaining and shock-absorbing properties. Glucosamine HCl provides glucosamine without the sulfate. Most clinical research on glucosamine and osteoarthritis has been conducted using glucosamine sulfate. This formula uses glucosamine sulfate at 500mg per capsule, providing 1,500mg per daily dose (3 capsules).

What Is MSM?

Methylsulfonylmethane (MSM), also known as dimethyl sulfone (DMSO2), is an organosulfur compound a naturally occurring sulfur-containing compound. It is found in small amounts in many foods including fruits, vegetables, milk, fish, and grains. MSM is a white, odourless, water-soluble crystalline solid. It is a source of bioavailable organic sulfur.

Sulfur is a component of collagen, keratin, and other structural proteins, and is involved in the formation of disulfide bonds that contribute to the structural integrity of connective tissue. Sulfur is also a component of cartilage proteoglycans. This formula provides 500mg of MSM per capsule, delivering 1,500mg per daily dose (3 capsules).

Why Glucosamine Sulfate and MSM Together?

Both glucosamine sulfate and MSM provide sulfur to the body, but through different mechanisms. Glucosamine sulfate provides glucosamine (a cartilage building block) and sulfate (a component of cartilage proteoglycans). MSM provides organic sulfur (dimethyl sulfone) as an additional source of bioavailable sulfur for connective tissue. The combination provides both the structural building block (glucosamine) and additional sulfur support (MSM) in a single formula.

Why 3 Times Per Day?

The recommended dose is 1 capsule, 3 times per day with food. Dividing the daily dose into 3 separate doses (rather than taking all 3 capsules at once) maintains more consistent levels of glucosamine and MSM in the body throughout the day. The instruction to avoid taking at bedtime means the 3 doses should be spread through waking hours, for example with breakfast, lunch, and dinner.

Why Does This Take at Least 1 Month to Work?

Glucosamine and MSM are not fast-acting like pain medications. They work by providing building blocks and sulfur for cartilage and connective tissue, which are slow-turnover tissues. The Health Canada approved duration of use for this formula is a minimum of 1 month to see beneficial effects. The 300-capsule bottle provides a 100-day supply at 3 capsules per day approximately 3.3 months which is well suited to the minimum trial period and allows for continued use beyond the initial month.

Understanding the Dose and Supply

The recommended dose is 1 capsule, 3 times per day with food. At 300 capsules and 3 capsules per day, one bottle provides a 100 day supply (approximately 3.3 months). Per daily dose (3 capsules): Glucosamine sulfate 1,500mg, MSM 1,500mg.

Understanding the Ingredient Content

Glucosamine (Glucosamine sulfate): 500mg per capsule (1,500mg per daily dose)
MSM (Methylsulfonylmethane, Dimethyl sulfone): 500mg per capsule (1,500mg per daily dose)
Suggested Use: Adults: 1 capsule, 3 times per day with food. Avoid taking at bedtime.
Duration of use: Use for a minimum of 1 month to see beneficial effects.
Capsules per bottle: 300 (100 day supply at 3 capsules per day)
Non Medicinal Ingredients: Magnesium Stearate, Microcrystalline Cellulose, Hypromellose

Who May Consider This Product

• Adults seeking a glucosamine sulfate and MSM formula for joint health
• Those who want 1,500mg glucosamine sulfate and 1,500mg MSM per daily dose
• Those who want a Health Canada approved joint health formula (NPN 80058087) made in Canada
• Those who want a large bottle (300 capsules, 100 day supply) for extended use

Consult a health care practitioner before use if: you are pregnant or breastfeeding. If symptoms worsen, consult a health care practitioner.

Note on shellfish source: Glucosamine sulfate is typically derived from crustacean shells. Verify the source of glucosamine sulfate in this formula before use if you have a shellfish allergy or follow a vegan diet. Confirm with Nutridom before purchasing if this is a concern.

Quality and Purity

• Health Canada approved (NPN 80058087)
• Glucosamine sulfate 500mg + MSM 500mg per capsule
• 1,500mg each per daily dose
• 300 capsules (100 day supply)
• Made in Canada

Storage

Store in airtight container, protected from light. Store in a cool, dry place. Keep out of reach of children.

Safety Information and Cautions

Consult a health care practitioner prior to use if you are pregnant or breastfeeding.

If symptoms worsen, consult a health care practitioner.

Use for a minimum of 1 month to see beneficial effects.

Some people may experience mild gastrointestinal disturbances such as diarrhea, abdominal pain, heartburn, nausea and vomiting; in which case, discontinue use.

This product is not intended to diagnose, treat, cure, or prevent any disease.

Keep out of reach of children.

About This Product

What it is: Glucosamine (Glucosamine sulfate) 500mg + MSM (Methylsulfonylmethane) 500mg per capsule. 1,500mg each per daily dose (3 capsules). 300 capsules (100 day supply).

What it does: Helps to relieve joint pain associated with osteoarthritis (of the knee). Helps to protect against the deterioration of cartilage. A factor in maintaining healthy cartilage and/or joint health (NPN 80058087).

Why glucosamine sulfate: Glucosamine sulfate is the form used in most clinical research on osteoarthritis. It provides both glucosamine (a cartilage building block) and sulfate (a component of cartilage proteoglycans). Glucosamine HCl provides glucosamine without the sulfate.

Why MSM: MSM (Methylsulfonylmethane) is a source of bioavailable organic sulfur. Sulfur is a component of collagen, connective tissue, and cartilage proteoglycans. Combined with glucosamine sulfate, this formula provides sulfur from two sources.

How to take it: Adults: 1 capsule, 3 times per day with food. Avoid at bedtime. Use for a minimum of 1 month to see beneficial effects. 300 capsules = 100 day supply (approximately 3.3 months).

Who it’s for: Adults. Consult a health care practitioner before use if pregnant or breastfeeding. If symptoms worsen, consult a health care practitioner. Verify glucosamine source if you have a shellfish allergy.

Where it’s made: Canada. Health Canada approved (NPN 80058087).