Nutridom Serrapeptase 120,000 SPU (60 Veggie Capsules)

Medicinal Ingredients (per capsule):
120,000 Serrapeptidase Unit...60 mg

Non-Medicinal Ingredients:
Brown rice flour, Hypromellose (vegetable capsule shell), Ethyl cellulose(Enteric coating)

Proteolytic enzyme.
Mucolytic enzyme that helps break down mucous.
Helps to reduce symptoms such as: pain, quantity of secretion, inability to perceive smell from ear, nose and/or throat infections.

Duration of Use:
Consult a health care practitioner for use beyond 7 days

Recommended Dose:
Adults: 1 Tablet 1 times per day.
Take 2 hours after a meal

Cautions and Warnings:
If symptoms persist or worsen, discontinue use and consult a health care practitioner. If you are pregnant or breastfeeding, consult a health care practitioner prior to use. If you have a gastrointestinal lesion/ulcer, are taking anticoagulant/blood thinner or anti-inflammatory medication, or are having surgery, consult a health care practitioner prior to use.

Known Adverse Reactions:
Hypersensitivity/allergy has been known to occur; in which case, discontinue use.

What is Serrapeptase?

Serrapeptase is a protelytic enzyme produced by serratia bacteria living in silkworms. Serrapeptase, like other proteolytic enzymes, helps break down proteins into smaller molecules. This can promote healing by reducing fluid and debris accumulation that can occur around tissue when an injury happens. Researchers have applied this unique characteristic to modern medicine, utilizing the enzyme for its potential anti-inflammatory activity.

What makes Serrapeptase interesting and distinct from other enzymes is that it affects only non-living tissues. This is due to Serrapeptase ability to target specific proteins. According to Health Canada, serrapeptase reduces swelling and pain from inflammation. Researchers think that enzymes like serrapeptase work to reduce inflammation by facilitating immune cell movement and regulating levels of lymphocytes at the site of inflammation. This enzyme seems to work in part by breaking down cyclooxygenase. Cyclooxygenase is an enzyme responsible for producing different inflammatory molecules. An additional property of serrapeptase is to decrease mucus production, which can be particularly helpful with certain ear, nose and throat conditions.

Reducing Pain

Pain is triggered by the presence of a protein called amine. When tissue is inflamed, an amine called bradykinin causes pain and soreness. Serrapeptase has been indicated to block the release of bradykinin, thus reducing pain.

Reducing Inflammation

Serrapeptase is known to break down fibrin, a protein involved in blood clotting. This helps to contain infection at the initial site. In prolonged inflammation, fibrin converts healthy tissue to a fibrous matrix, which maintains the inflammatory responses.

Infections and Wound Healing

Serrapeptase has been shown to help prevent infections, and assist with wound healing. This is thought to be due to the caseinolytic properties of serrapeptase. Thereby promoting recovery from infections and injuries because it’s been shown to:
• decrease swelling
• reduce formation of scar tissue
• reduce excess mucus
• break down excess proteins
• decrease permeability of capillaries (small blood vessels)
• control histamine responses
• control skin temperature
• facilitate the absorption of decomposed products through blood and the lymphatic system
• inhibit the formation of biofilm

Q: When Should I Use This Product?

A: When taken orally, serrapeptase is easily destroyed and deactivated by your stomach acid before it has a chance to reach your instestines to be absorbed. For this reason, dietary supplements containing serrapeptase should be enteric-coated, which prevents them from being dissolved in the stomach and allows for release in the intestine. The recommendation generally is to take serrapeptase on an empty stomach or at least 30 mins before eating or two hours after finishing a meal. If you take certain blood thinning medications, such as warfarin, you may need to look at other supplemental options.

Q: Who Can Benefit?

A: Research to date shows that serrepeptase is generally well-tolerated by adults. However, more research is still needed to show its long-term safety. Those who are looking for a supplement to reduce pain and inflammation with minimal side effects could benefit from using serrapeptase. Additionally, someone with a cold or ear/nose/throat infection where excess mucus production is an issue could also benefit.