Alpha Lipoic Acid 600 mg | DL-ALA | 60 Vcaps

Alpha lipoic acid (ALA) is a naturally occurring organosulfur compound synthesized in small amounts by the body. It functions as an essential cofactor for two critical mitochondrial enzyme complexes the pyruvate dehydrogenase complex (PDC) and the alpha ketoglutarate dehydrogenase complex (KGDC) both central to cellular energy metabolism. At supplemental doses, ALA acts as a universal antioxidant active in both aqueous and lipid cellular environments, an antioxidant network regenerator (regenerating vitamin C, vitamin E, and glutathione), and a glucose metabolism support agent through AMPK activation and GLUT4 translocation.

R-ALA is the naturally occurring, biologically active enantiomer of alpha-lipoic acid found in the body. S-ALA is the synthetic mirror image enantiomer. DL-ALA is the racemic 50:50 mixture of both, produced by chemical synthesis. DL-ALA is more chemically stable than pure R-ALA, less prone to polymerization at room temperature, and is the form used in the majority of clinical research on alpha lipoic acid. Each 600 mg DL-ALA capsule provides approximately 300 mg of biologically active R-ALA.

Most antioxidants operate in only one cellular environment vitamin C works in aqueous (water-based) compartments; vitamin E works in lipid (fat-based) membranes. ALA and its reduced form DHLA are active in both simultaneously, protecting water soluble and fat-soluble cellular components with a single molecule. DHLA also regenerates vitamin C, vitamin E, and glutathione, extending the antioxidant activity of the entire network. This dual-environment activity and antioxidant network regeneration is why ALA is classified as a universal antioxidant.

At supplemental doses, free ALA activates AMPK (AMP activated protein kinase), which promotes GLUT4 glucose transporter translocation to the cell surface in muscle and adipose tissue, enhancing insulin-stimulated glucose uptake. This is the mechanism underlying the Health Canada licensed glucose metabolism claim (NPN 80122537). Consult a healthcare practitioner before use if you have diabetes or are taking antidiabetic medications. Stop use if you experience symptoms of low blood sugar (sweating, paleness, chills, headache, dizziness, or confusion).

Consult a healthcare practitioner before use if you are pregnant, breastfeeding, have diabetes, or are taking antidiabetic medications. Stop use and consult a healthcare practitioner immediately if you experience sweating, paleness, chills, headache, dizziness, or confusion these may be symptoms of serious low blood sugar. Keep out of reach of children.