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Resveratrol 500mg | 99% Trans Resveratrol | Japanese Knotweed | 60 Vcaps

500mg of 99% pure trans-resveratrol per vegan capsule, extracted from Japanese Knotweed root (Reynoutria japonica) one of the richest natural plant sources of trans resveratrol. Polyphenol antioxidant. Cellular health and cardiovascular wellness support. 

Key Features

  • 500mg trans-resveratrol per vcap 99% purity. Active stilbenoid form.
  • Japanese Knotweed root source Reynoutria japonica. Highest natural plant concentration of trans-resveratrol.
  • Health Canada licensed NPN 80140494 Made in Canada.
  • Vegan capsule Hypromellose. No gelatin.
  • Non-GMO. Gluten free. Dairy free.
  • 60 vcaps 60 day supply at 1 vcap per day.

Recommended Use

Adults: 1 capsule daily, or as directed by a healthcare practitioner. Take with food. Consult a healthcare practitioner before use if you are pregnant or breastfeeding, have a hormone sensitive condition, or are taking medications including blood thinners or antiplatelet agents.

Trans-Resveratrol: Source, Form, and Mechanism

Resveratrol is a stilbenoid polyphenol produced by certain plants as a phytoalexin a defense compound synthesized in response to stress, injury, UV radiation, or fungal infection. It exists in two geometric isomers: trans-resveratrol and cis-resveratrol. Trans resveratrol is the biologically active form it is more stable, more bioavailable, and the form that has been most extensively studied for its antioxidant and cellular health properties. Cis-resveratrol is less stable and converts readily to the trans form under light exposure.

Japanese Knotweed root (Reynoutria japonica) is the primary commercial source of high purity trans resveratrol. It contains significantly higher concentrations of trans resveratrol than grapes, berries, or red wine making it the most practical botanical source for concentrated supplementation. This formula provides 500mg of 99% pure trans-resveratrol per capsule, standardized to the active isomer.

Trans resveratrol acts as a direct antioxidant, scavenging reactive oxygen species and chelating metal ions that catalyze free radical generation. It also activates SIRT1 (sirtuin-1), a NAD⁺-dependent deacetylase involved in cellular energy sensing, mitochondrial biogenesis, and the regulation of cellular stress response pathways. SIRT1 activation by resveratrol has been studied in the context of cellular longevity signalling, metabolic regulation, and cardiovascular function. Additionally, trans-resveratrol modulates NF-κB signalling, supporting healthy inflammatory response at the cellular level.

Who This Is For

  • Adults seeking a high purity, high-potency trans resveratrol supplement for daily antioxidant and cellular health support
  • Those who want 99% pure trans resveratrol from Japanese Knotweed in a Health Canada licensed, vegan, Canadian made formula
  • Those interested in polyphenol supplementation for cardiovascular wellness and healthy aging support

Consult a healthcare practitioner before use if you are pregnant or breastfeeding, have a hormone sensitive condition, or are taking blood-thinning or antiplatelet medications. Keep out of reach of children.

Medicinal Ingredient (per vcap)

  • Trans-Resveratrol (Reynoutria japonica, root) 500mg 99% purity. Japanese Knotweed. NPN 80140494.

Non-medicinal ingredient: Hypromellose (vegetable capsule shell). Vegan. Non-GMO. Gluten free. Dairy free.

Quality and Trust

  • NPN 80140494 Licensed by Health Canada as a Natural Health Product
  • Made in Canada
  • 500mg trans-resveratrol per vcap 99% purity. Active stilbenoid form.
  • Japanese Knotweed root Reynoutria japonica. Highest natural plant concentration.
  • Vegan capsule Hypromellose. No gelatin.
  • Non-GMO. Gluten free. Dairy free.
  • 60 vcaps

Storage

Store in a cool, dry place away from direct sunlight and moisture. Keep the bottle tightly sealed after each use. Do not use if the seal is broken or missing. Keep out of reach of children.

Cautions

Consult a healthcare practitioner before use if you are pregnant or breastfeeding, have a hormone-sensitive condition, or are taking blood thinning or antiplatelet medications. Keep out of reach of children.

NPN 80140494.

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Resveratrol 500mg | 99% Trans Resveratrol | Japanese Knotweed | 60 Vcaps

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Health Canada Licensed Natural Health Product (NPN 80140494)

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Resveratrol 500mg | 99% Trans Resveratrol | Japanese Knotweed | 60 Vcaps

500mg of 99% pure trans-resveratrol per vegan capsule, extracted from Japanese Knotweed root (Reynoutria japonica) one of the richest natural plant sources of trans resveratrol. Polyphenol antioxidant. Cellular health and cardiovascular wellness support. 

Key Features

  • 500mg trans-resveratrol per vcap 99% purity. Active stilbenoid form.
  • Japanese Knotweed root source Reynoutria japonica. Highest natural plant concentration of trans-resveratrol.
  • Health Canada licensed NPN 80140494 Made in Canada.
  • Vegan capsule Hypromellose. No gelatin.
  • Non-GMO. Gluten free. Dairy free.
  • 60 vcaps 60 day supply at 1 vcap per day.

Recommended Use

Adults: 1 capsule daily, or as directed by a healthcare practitioner. Take with food. Consult a healthcare practitioner before use if you are pregnant or breastfeeding, have a hormone sensitive condition, or are taking medications including blood thinners or antiplatelet agents.

Trans-Resveratrol: Source, Form, and Mechanism

Resveratrol is a stilbenoid polyphenol produced by certain plants as a phytoalexin a defense compound synthesized in response to stress, injury, UV radiation, or fungal infection. It exists in two geometric isomers: trans-resveratrol and cis-resveratrol. Trans resveratrol is the biologically active form it is more stable, more bioavailable, and the form that has been most extensively studied for its antioxidant and cellular health properties. Cis-resveratrol is less stable and converts readily to the trans form under light exposure.

Japanese Knotweed root (Reynoutria japonica) is the primary commercial source of high purity trans resveratrol. It contains significantly higher concentrations of trans resveratrol than grapes, berries, or red wine making it the most practical botanical source for concentrated supplementation. This formula provides 500mg of 99% pure trans-resveratrol per capsule, standardized to the active isomer.

Trans resveratrol acts as a direct antioxidant, scavenging reactive oxygen species and chelating metal ions that catalyze free radical generation. It also activates SIRT1 (sirtuin-1), a NAD⁺-dependent deacetylase involved in cellular energy sensing, mitochondrial biogenesis, and the regulation of cellular stress response pathways. SIRT1 activation by resveratrol has been studied in the context of cellular longevity signalling, metabolic regulation, and cardiovascular function. Additionally, trans-resveratrol modulates NF-κB signalling, supporting healthy inflammatory response at the cellular level.

Who This Is For

  • Adults seeking a high purity, high-potency trans resveratrol supplement for daily antioxidant and cellular health support
  • Those who want 99% pure trans resveratrol from Japanese Knotweed in a Health Canada licensed, vegan, Canadian made formula
  • Those interested in polyphenol supplementation for cardiovascular wellness and healthy aging support

Consult a healthcare practitioner before use if you are pregnant or breastfeeding, have a hormone sensitive condition, or are taking blood-thinning or antiplatelet medications. Keep out of reach of children.

Medicinal Ingredient (per vcap)

  • Trans-Resveratrol (Reynoutria japonica, root) 500mg 99% purity. Japanese Knotweed. NPN 80140494.

Non-medicinal ingredient: Hypromellose (vegetable capsule shell). Vegan. Non-GMO. Gluten free. Dairy free.

Quality and Trust

  • NPN 80140494 Licensed by Health Canada as a Natural Health Product
  • Made in Canada
  • 500mg trans-resveratrol per vcap 99% purity. Active stilbenoid form.
  • Japanese Knotweed root Reynoutria japonica. Highest natural plant concentration.
  • Vegan capsule Hypromellose. No gelatin.
  • Non-GMO. Gluten free. Dairy free.
  • 60 vcaps

Storage

Store in a cool, dry place away from direct sunlight and moisture. Keep the bottle tightly sealed after each use. Do not use if the seal is broken or missing. Keep out of reach of children.

Cautions

Consult a healthcare practitioner before use if you are pregnant or breastfeeding, have a hormone-sensitive condition, or are taking blood thinning or antiplatelet medications. Keep out of reach of children.

NPN 80140494.