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Vitamin D3 1000 IU K2 120 mcg MK7 with MCT oil 120 softgels
Vitamin D3 K2 MK7 supplement 1000 IU 120 mcg softgels
Vitamin D3 1000 IU MCT oil supplement 500 softgels
Vitamin D3 K2 supplement bottle 300 softgels with MCT oil
Vitamin D3 1000 IU K2 120 mcg MK7 with MCT oil 120 softgels

Vitamin D3 (cholecalciferol) 1,000 IU and Vitamin K2 (menaquinone-7, MK-7, natto-derived) 120 mcg per softgel, in MCT oil from non-GMO coconut oil. Helps in the development and maintenance of bones and teeth. Helps in the absorption and use of calcium. A factor in the maintenance of good health.

Vitamin D3 increases calcium absorption from the intestine. Vitamin K2 as MK-7 activates two key proteins that direct that calcium where it belongs: osteocalcin, which binds calcium into bone matrix, and Matrix Gla Protein (MGP), which inhibits calcium deposition in arterial walls and soft tissue. MK-7 has an approximately 3-day half life, giving it sustained activity in peripheral tissues including bone and blood vessel walls between daily doses.

Why MCT Oil?

D3 and K2 are fat soluble vitamins that require fat for absorption. MCT oil (C8 and C10 medium chain triglycerides from non GMO coconut oil) is absorbed directly into the portal vein without requiring bile emulsification providing efficient fat soluble vitamin absorption that does not depend on a fat containing meal.

Vitamin D3 1000 IU + K2 120mcg MK-7 | MCT Oil | 120 Softgels

$22.99
5.0 (4)

Health Canada Licensed Natural Health Product (NPN 80116252)

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Vitamin D3 (cholecalciferol) 1,000 IU and Vitamin K2 (menaquinone-7, MK-7, natto-derived) 120 mcg per softgel, in MCT oil from non-GMO coconut oil. Helps in the development and maintenance of bones and teeth. Helps in the absorption and use of calcium. A factor in the maintenance of good health.

Vitamin D3 increases calcium absorption from the intestine. Vitamin K2 as MK-7 activates two key proteins that direct that calcium where it belongs: osteocalcin, which binds calcium into bone matrix, and Matrix Gla Protein (MGP), which inhibits calcium deposition in arterial walls and soft tissue. MK-7 has an approximately 3-day half life, giving it sustained activity in peripheral tissues including bone and blood vessel walls between daily doses.

Why MCT Oil?

D3 and K2 are fat soluble vitamins that require fat for absorption. MCT oil (C8 and C10 medium chain triglycerides from non GMO coconut oil) is absorbed directly into the portal vein without requiring bile emulsification providing efficient fat soluble vitamin absorption that does not depend on a fat containing meal.

Supplement Facts

Supplement Facts

Serving Size: 1 Softgel

Servings Per Container: 120

Ingredient
Amount Per
Serving
% Daily
Value
Vitamin D3 (Cholecalciferol)
1,000 IU (25 mcg)
*
Vitamin K2 (Menaquinone-7, MK-7, Natto-Derived)
120 mcg
*

† Daily Value not established

Other Ingredients:
Medium Chain Triglyceride Oil (from Non-GMO Coconut Oil), Bovine Gelatin (Capsule Shell).

Clinical Research

Vitamin D and intestinal calcium absorption: mechanisms and clinical implications

Molecular and Cellular Endocrinology, 2011

This mechanistic review examined the role of Vitamin D3 (cholecalciferol) and its active metabolite 1,25-dihydroxyvitamin D (calcitriol) in intestinal calcium absorption. Vitamin D3 is converted in the liver to 25-hydroxyvitamin D (25(OH)D) and then in the kidney to calcitriol, which binds to the Vitamin D receptor (VDR) in intestinal enterocytes and upregulates expression of calcium transport proteins particularly TRPV6 (epithelial calcium channel) and calbindin-D9k (intracellular calcium binding protein) increasing transcellular calcium transport across the intestinal epithelium. The review documented that adequate Vitamin D status is essential for efficient calcium absorption, with deficiency associated with significantly reduced calcium uptake from the diet and compensatory secondary hyperparathyroidism.

Three year low dose menaquinone 7 supplementation helps decrease bone loss in healthy postmenopausal women

Osteoporosis International, 2013

This randomized, double blind, placebo controlled trial examined the effects of 180mcg MK-7 daily supplementation on bone mineral density and bone strength indices in 244 healthy postmenopausal women over 3 years. MK-7 supplementation significantly improved vitamin K status (measured by carboxylated osteocalcin levels) and was associated with significantly less age related bone mineral density loss at the lumbar spine and femoral neck compared to placebo. Bone strength indices also showed significant improvement in the MK-7 group. The authors concluded that MK-7 supplementation at 180mcg per day for 3 years improved bone health in healthy postmenopausal women, with the effects attributed to MK-7's role in activating osteocalcin the vitamin K-dependent protein that binds calcium into bone matrix.

Combined supplementation of vitamin D3 and K2 and arterial stiffness: a systematic review

Nutrients, 2020

This systematic review examined clinical evidence for the combined effects of Vitamin D3 and K2 supplementation on arterial stiffness a key marker of cardiovascular health across randomized controlled trials. The proposed mechanism centers on Matrix Gla Protein (MGP), a vitamin K-dependent protein that is the most potent known inhibitor of vascular calcification. MGP requires vitamin K2 carboxylation to be active; uncarboxylated MGP (ucMGP) is unable to inhibit calcium deposition in arterial walls. Vitamin D3 increases calcium availability systemically, while K2 activates MGP to direct calcium away from vascular tissue. Several included trials demonstrated that combined D3 + K2 supplementation was associated with reductions in arterial stiffness markers compared to D3 alone or placebo, with the magnitude of effect correlating with improvements in MGP carboxylation status. The review highlighted that K2 as MK-7 due to its longer half life compared to MK-4 was the most consistently effective K2 form for MGP activation in peripheral vascular tissue.

Research information is provided for educational purposes and does not replace the product's approved label information.

Frequently Asked Questions

Why are Vitamin D3 and K2 combined in this formula?

Vitamin D3 and K2 work through complementary mechanisms that make them more effective together than separately. Vitamin D3 (cholecalciferol) increases calcium absorption from the intestine a well established and Health Canada licensed mechanism. However, increased calcium absorption without proper routing can result in calcium circulating in the bloodstream without being directed to its intended destination. Vitamin K2 as MK-7 (menaquinone-7) activates two key vitamin K dependent proteins: osteocalcin, which binds calcium into bone matrix (supporting bone density and strength), and Matrix Gla Protein (MGP), which inhibits calcium deposition in arterial walls and soft tissue (supporting vascular health). In other words, D3 increases calcium availability, and K2 directs where that calcium goes into bones and teeth rather than soft tissue. MK-7 has an approximately 3-day half life, giving it sustained activity in peripheral tissues including bone and blood vessel walls between daily dose

What are the benefits of Vitamin D3?

Vitamin D3 helps the body absorb and use calcium and phosphorus, which are important for maintaining strong bones and teeth. It also supports normal immune system function.

Why combine Vitamin D3 with Vitamin K2?

Vitamin D3 helps increase calcium absorption, while vitamin K2 supports the normal utilization of calcium in the body. Together, they provide complementary support for bone and mineral health.

Why does this formula contain MCT oil?

MCT oil acts as a carrier for the fat soluble vitamins D3 and K2 and helps provide them in a convenient oil based softgel format.

Canadian-Made

Lab-Tested

Health Canada Approved

20 Years of Research

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